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The quantitative structure-activity relationship (QSAR) regression model is a commonly used technique for predicting biological activities of compounds using their molecular descriptors. Predictions from QSAR models can help, for example,…

Biomolecules · Quantitative Biology 2023-04-04 Yuting Xu , Andy Liaw , Robert P. Sheridan , Vladimir Svetnik

In finite mixture models, apart from underlying mixing measure, true kernel density function of each subpopulation in the data is, in many scenarios, unknown. Perhaps the most popular approach is to choose some kernel functions that we…

Statistics Theory · Mathematics 2017-09-26 Nhat Ho , XuanLong Nguyen , Ya'acov Ritov

Meta distributions (MDs) are refined performance metrics in wireless networks modeled using point processes. While there is no known method to directly calculate MDs, the moments of the underlying conditional distributions (given the point…

Information Theory · Computer Science 2018-05-01 Martin Haenggi

The quark meson (linear sigma) model with linearized fluctuations displays at a critical end point the onset of a curve of first-order phase transitions (FOPTs) located at non-zero chemical potentials and temperatures below a certain…

High Energy Physics - Phenomenology · Physics 2017-02-01 Falk Wunderlich , Burkhard Kampfer

We consider fermion (or determinantal) random point fields on Euclidean space $\mbR^d$. Given a bounded, translation invariant, and positive definite integral operator $J$ on $L^2(\mbR^d)$, we introduce a determinantal interaction for a…

Mathematical Physics · Physics 2007-05-23 Hyun Jae Yoo

This article proposes a new way to construct computationally efficient `wrappers' around fine scale, microscopic, detailed descriptions of dynamical systems, such as molecular dynamics, to make predictions at the macroscale `continuum'…

Dynamical Systems · Mathematics 2017-03-06 Hammad Alotaibi , Barry Cox , A. J. Roberts

Functional principal components (FPC's) provide the most important and most extensively used tool for dimension reduction and inference for functional data. The selection of the number, d, of the FPC's to be used in a specific procedure has…

Statistics Theory · Mathematics 2013-02-26 Stefan Fremdt , Lajos Horváth , Piotr Kokoszka , Josef G. Steinebach

The choice of molecular orbitals is decisive in configuration interaction calculations. In this letter, a democratic description of the ground and excited states follows an orthogonally constrained orbitals optimization to produce…

Quantum Physics · Physics 2023-02-16 Saad Yalouz , Vincent Robert

Conformational transitions are ubiquitous in biomolecular systems, have significant functional roles and are subject to evolutionary pressures. Here we provide a first theoretical framework for topological transition, i.e. conformational…

Disordered Systems and Neural Networks · Physics 2015-09-02 Alireza Mashaghi , Abolfazl Ramezanpour

The order parameter cumulants of infinite matrix product ground states are evaluated across a quantum phase transition. A scheme using the Binder cumulant, finite-entanglement scaling and scaling functions to obtain the critical point and…

Strongly Correlated Electrons · Physics 2020-01-01 Jason C. Pillay , Ian P. McCulloch

As well as arising naturally in the study of non-intersecting random paths, random spanning trees, and eigenvalues of random matrices, determinantal point processes (sometimes also called fermionic point processes) are relatively easy to…

Probability · Mathematics 2008-04-04 Steven N. Evans , Alex Gottlieb

We propose a simple method to estimate the parameters of a continuously measured quantum system, by fitting correlation functions of the measured signal. We demonstrate the approach in simulation, both on toy examples and on a recent…

Quantum Physics · Physics 2024-10-17 Pierre Guilmin , Pierre Rouchon , Antoine Tilloy

Function-on-function regression has been a topic of substantial interest due to its broad applicability, where the relation between functional predictor and response is concerned. In this article, we propose a new framework for modeling the…

Methodology · Statistics 2025-06-04 Tongyu Li , Fang Yao

Various aspects of the four point function for scalar fields in conformally invariant theories are analysed. This depends on an arbitrary function of two conformal invariants u,v. A recurrence relation for the function corresponding to the…

High Energy Physics - Theory · Physics 2009-10-31 F. A. Dolan , H. Osborn

Transition state or minimum energy path finding methods constitute a routine component of the computational chemistry toolkit. Standard analysis involves trajectories conventionally plotted in terms of the relative energy to the initial…

Chemical Physics · Physics 2026-03-09 Rohit Goswami

Determinantal point processes (DPPs) offer an elegant tool for encoding probabilities over subsets of a ground set. Discrete DPPs are parametrized by a positive semidefinite matrix (called the DPP kernel), and estimating this kernel is key…

Machine Learning · Computer Science 2015-10-12 Zelda Mariet , Suvrit Sra

The computation of dynamical response functions is central to many problems in condensed matter physics. Owing to the rapid growth of quantum correlations following a quench, classical methods face significant challenges even if an…

Quantum Physics · Physics 2025-05-09 Esther Cruz , Dominik S. Wild , Mari Carmen Bañuls , J. Ignacio Cirac

Optimal control theory is a powerful tool for improving figures of merit in quantum information tasks. Finding the solution to any optimal control problem via numerical optimization depends crucially on the choice of the optimization…

We develop a semi-parametric state-space model for time-series data with latent regime transitions. Classical Markov-switching models use fixed parametric transition functions, such as logistic or probit links, which restrict flexibility…

Machine Learning · Statistics 2026-04-08 Prakul Sunil Hiremath

Various biological system models have been proposed in systems biology, which are based on the complex biological reactions kinetic of various components. These models are not practical because we lack of kinetic information. In this paper,…

Quantitative Methods · Quantitative Biology 2011-02-19 Weidong Huang , Chundu Wu , Bingjia Xiao , Weidong Xia
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