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Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Darvin Yi , Mu Zhou , Zhao Chen , Olivier Gevaert

Large annotated datasets are required for training deep learning models, but in medical imaging data sharing is often complicated due to ethics, anonymization and data protection legislation. Generative AI models, such as generative…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Muhammad Usman Akbar , Måns Larsson , Anders Eklund

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histological sub-regions, i.e., peritumoral edema, necrotic core, enhancing and non-enhancing…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Marco Domenico Cirillo , David Abramian , Anders Eklund

In this study, we focus on brain tumor sequence registration between pre-operative and follow-up Magnetic Resonance Imaging (MRI) scans of brain glioma patients, in the context of Brain Tumor Sequence Registration challenge (BraTS-Reg…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

With the development of image segmentation in computer vision, biomedical image segmentation have achieved remarkable progress on brain tumor segmentation and Organ At Risk (OAR) segmentation. However, most of the research only uses single…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Kuan-Lun Tseng , Winston Hsu , Chun-ting Wu , Ya-Fang Shih , Fan-Yun Sun

Missing scans are inevitable in longitudinal studies due to either subject dropouts or failed scans. In this paper, we propose a deep learning framework to predict missing scans from acquired scans, catering to longitudinal infant studies.…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Yunzhi Huang , Sahar Ahmad , Luyi Han , Shuai Wang , Zhengwang Wu , Weili Lin , Gang Li , Li Wang , Pew-Thian Yap

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Computer-assisted diagnosis (CAD) based on deep learning has become a crucial diagnostic technology in the medical industry, effectively improving diagnosis accuracy. However, the scarcity of brain tumor Magnetic Resonance (MR) image…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Panjian Huang , Xu Liu , Yongzhen Huang

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Synthesizing healthy brain scans from diseased brain scans offers a potential solution to address the limitations of general-purpose algorithms, such as tissue segmentation and brain extraction algorithms, which may not effectively handle…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Ruizhi Zhu , Xinru Zhang , Haowen Pang , Chundan Xu , Chuyang Ye

In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Mikael Agn , Per Munck af Rosenschöld , Oula Puonti , Michael J. Lundemann , Laura Mancini , Anastasia Papadaki , Steffi Thust , John Ashburner , Ian Law , Koen Van Leemput

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR), and the Medical Image Computing and Computer Assisted…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Ujjwal Baid , Satyam Ghodasara , Suyash Mohan , Michel Bilello , Evan Calabrese , Errol Colak , Keyvan Farahani , Jayashree Kalpathy-Cramer , Felipe C. Kitamura , Sarthak Pati , Luciano M. Prevedello , Jeffrey D. Rudie , Chiharu Sako , Russell T. Shinohara , Timothy Bergquist , Rong Chai , James Eddy , Julia Elliott , Walter Reade , Thomas Schaffter , Thomas Yu , Jiaxin Zheng , Ahmed W. Moawad , Luiz Otavio Coelho , Olivia McDonnell , Elka Miller , Fanny E. Moron , Mark C. Oswood , Robert Y. Shih , Loizos Siakallis , Yulia Bronstein , James R. Mason , Anthony F. Miller , Gagandeep Choudhary , Aanchal Agarwal , Cristina H. Besada , Jamal J. Derakhshan , Mariana C. Diogo , Daniel D. Do-Dai , Luciano Farage , John L. Go , Mohiuddin Hadi , Virginia B. Hill , Michael Iv , David Joyner , Christie Lincoln , Eyal Lotan , Asako Miyakoshi , Mariana Sanchez-Montano , Jaya Nath , Xuan V. Nguyen , Manal Nicolas-Jilwan , Johanna Ortiz Jimenez , Kerem Ozturk , Bojan D. Petrovic , Chintan Shah , Lubdha M. Shah , Manas Sharma , Onur Simsek , Achint K. Singh , Salil Soman , Volodymyr Statsevych , Brent D. Weinberg , Robert J. Young , Ichiro Ikuta , Amit K. Agarwal , Sword C. Cambron , Richard Silbergleit , Alexandru Dusoi , Alida A. Postma , Laurent Letourneau-Guillon , Gloria J. Guzman Perez-Carrillo , Atin Saha , Neetu Soni , Greg Zaharchuk , Vahe M. Zohrabian , Yingming Chen , Milos M. Cekic , Akm Rahman , Juan E. Small , Varun Sethi , Christos Davatzikos , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , John B. Freymann , Justin S. Kirby , Benedikt Wiestler , Priscila Crivellaro , Rivka R. Colen , Aikaterini Kotrotsou , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Hassan Fathallah-Shaykh , Roland Wiest , Andras Jakab , Marc-Andre Weber , Abhishek Mahajan , Bjoern Menze , Adam E. Flanders , Spyridon Bakas

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Another year of the multimodal brain tumor segmentation challenge (BraTS) 2021 provides an even larger dataset to facilitate collaboration and research of brain tumor segmentation methods, which are necessary for disease analysis and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Md Mahfuzur Rahman Siddiquee , Andriy Myronenko

In medical imaging, a general problem is that it is costly and time consuming to collect high quality data from healthy and diseased subjects. Generative adversarial networks (GANs) is a deep learning method that has been developed for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Per Welander , Simon Karlsson , Anders Eklund

Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

Machine Learning · Computer Science 2026-01-13 Hasan M Jamil

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Gliomas are among the most aggressive cancers, characterized by high mortality rates and complex diagnostic processes. Existing studies on glioma diagnosis and classification often describe issues such as high variability in imaging data,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Abdur Rahman , Mohaimenul Azam Khan Raiaan , Arefin Ittesafun Abian , Yan Zhang , Mirjam Jonkman , Sami Azam

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin