Related papers: Improving mitosis detection on histopathology imag…
The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts. However, model training is often…
In this paper we propose a workflow to detect and track mitotic cells in time-lapse microscopy image sequences. In order to avoid the requirement for cell lines expressing fluorescent markers and the associated phototoxicity, phase contrast…
Background: Histopathology is an important modality for the diagnosis and management of many diseases in modern healthcare, and plays a critical role in cancer care. Pathology samples can be large and require multi-site sampling, leading to…
Hematoxylin and Eosin (H&E)-stained images are commonly used to detect nuclear or cancerous regions in cells from images captured by a microscope. Identifying cancer cytoplasm is crucial for determining the type of cancer; hence, obtaining…
Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…
This abstract presents our solution (Team Westwood) for mitosis detection and atypical mitosis classification in the MItosis DOmain Generalization (MIDOG) 2025 challenge. For mitosis detection, we trained an nnUNetV2 for initial mitosis…
Microscopic assessment of histopathology images is vital for accurate cancer diagnosis and treatment. Whole Slide Image (WSI) classification and captioning have become crucial tasks in computer-aided pathology. However, microscopic WSI face…
Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…
Atypical mitosis marks a deviation in the cell division process that has been shown be an independent prognostic marker for tumor malignancy. However, atypical mitosis classification remains challenging due to low prevalence, at times…
DNA methylation is an epigenetic mechanism that regulates gene expression by adding methyl groups to DNA. Abnormal methylation patterns can disrupt gene expression and have been linked to cancer development. To quantify DNA methylation,…
The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…
Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…
The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…
We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has…
Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…
The expansion of artificial intelligence (AI) in pathology tasks has intensified the demand for doctors' annotations in AI development. However, collecting high-quality annotations from doctors is costly and time-consuming, creating a…
In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…
We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…
According to some medical imaging techniques, breast histopathology images called Hematoxylin and Eosin are considered as the gold standard for cancer diagnoses. Based on the idea of dividing the pathologic image (WSI) into multiple…
Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…