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Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Topological descriptors have been increasingly utilized for capturing multiscale structural information in relational data. In this work, we consider various filtrations on the (box) product of graphs and the effect on their outputs on the…

Machine Learning · Computer Science 2026-02-09 Mattie Ji , Amauri H. Souza , Vikas Garg

Link prediction is an important learning task for graph-structured data. In this paper, we propose a novel topological approach to characterize interactions between two nodes. Our topological feature, based on the extended persistent…

Machine Learning · Computer Science 2021-06-15 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Chao Chen

Force-directed layouts belong to a popular class of methods used to position nodes in a node-link diagram. However, they typically lack direct consideration of global structures, which can result in visual clutter and the overlap of…

Human-Computer Interaction · Computer Science 2022-08-16 Bhavana Doppalapudi , Bei Wang , Paul Rosen

Balancing performance and interpretability in multivariate time series classification is a significant challenge due to data complexity and high dimensionality. This paper introduces PHeatPruner, a method integrating persistent homology and…

Machine Learning · Computer Science 2025-04-28 Anh-Duy Pham , Olivier Basole Kashongwe , Martin Atzmueller , Tim Römer

In this work, Transition Probability Matrix (TPM) is proposed as a new method for extracting the features of nodes in the graph. The proposed method uses random walks to capture the connectivity structure of a node's close neighborhood. The…

Machine Learning · Computer Science 2023-03-07 Sarmad N. Mohammed , Semra Gündüç

Persistent homology is a popular method for computing topological features of (metric) data. Standard approaches based on the \v{C}ech or Rips filtration are stable under small perturbations of the data, but highly sensitive to outliers.…

Algebraic Topology · Mathematics 2026-02-27 Pepijn Roos Hoefgeest , Lucas Slot

Compression aims to reduce the size of an input, while maintaining its relevant properties. For multi-parameter persistent homology, compression is a necessary step in any computational pipeline, since standard constructions lead to large…

Algebraic Topology · Mathematics 2022-08-17 Ulderico Fugacci , Michael Kerber , Alexander Rolle

Hyperuniformity refers to the suppression of density fluctuations at large scales. Typical for ordered systems, this property also emerges in several disordered physical and biological systems, where it is particularly relevant to…

Statistical Mechanics · Physics 2025-02-24 Abel H. G. Milor , Marco Salvalaglio

Probabilistic Latent Variable Models (LVMs) excel at modeling complex, high-dimensional data through lower-dimensional representations. Recent advances show that equipping these latent representations with a Riemannian metric unlocks…

Machine Learning · Computer Science 2025-05-20 Luis Augenstein , Noémie Jaquier , Tamim Asfour , Leonel Rozo

This paper introduces an unsupervised method to estimate the class separability of text datasets from a topological point of view. Using persistent homology, we demonstrate how tracking the evolution of embedding manifolds during training…

Machine Learning · Computer Science 2024-06-19 Kostis Gourgoulias , Najah Ghalyan , Maxime Labonne , Yash Satsangi , Sean Moran , Joseph Sabelja

Topological Data Analysis (TDA) is a novel statistical technique, particularly powerful for the analysis of large and high dimensional data sets. Much of TDA is based on the tool of persistent homology, represented visually via persistence…

Applications · Statistics 2017-11-07 Sarit Agami , Robert J. Adler

Node embedding learns low-dimensional vectors for nodes in the graph. Recent state-of-the-art embedding approaches take Personalized PageRank (PPR) as the proximity measure and factorize the PPR matrix or its adaptation to generate…

Machine Learning · Computer Science 2024-05-31 Xingyi Zhang , Zixuan Weng , Sibo Wang

We propose a practical computational framework for detecting structural changes in parameter-dependent topological data. In many applications, such as time-series data analysis, anomaly detection, and monitoring of systems under changing…

Algebraic Topology · Mathematics 2026-05-28 Satoshi Kanno , Rei Nishimura , Hiroshi Yamauchi , Yoshi-aki Shimada

Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable successes of numerous image processing methods that rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Pengfei Gu , Hongxiao Wang , Yejia Zhang , Huimin Li , Chaoli Wang , Danny Chen

This article studies the robust version of persistent homology based on trimming methodology to capture the geometric feature through support of the data in presence of outliers. Precisely speaking, the proposed methodology works when the…

Methodology · Statistics 2026-01-01 Tuhin Subhra Mahato , Subhra Sankar Dhar

We introduce graphcodes, a novel multi-scale summary of the topological properties of a dataset that is based on the well-established theory of persistent homology. Graphcodes handle datasets that are filtered along two real-valued scale…

Algebraic Topology · Mathematics 2024-05-24 Michael Kerber , Florian Russold

Understanding the magnetic fields of the Sun is essential for unraveling the underlying mechanisms driving solar activity. Integrating topological data analysis techniques into these investigations can provide valuable insights into the…

Solar and Stellar Astrophysics · Physics 2024-01-31 Pablo Santamarina Guerrero , Yukio Katsukawa , Shin Toriumi , David Orozco Suárez

Understanding the decision-making processes of large language models is critical given their widespread applications. To achieve this, we aim to connect a formal mathematical framework - zigzag persistence from topological data analysis -…

Computation and Language · Computer Science 2025-06-16 Yuri Gardinazzi , Karthik Viswanathan , Giada Panerai , Alessio Ansuini , Alberto Cazzaniga , Matteo Biagetti

Many multi-variate time series obtained in the natural sciences and engineering possess a repetitive behavior, as for instance state-space trajectories of industrial machines in discrete automation. Recovering the times of recurrence from…

Computational Geometry · Computer Science 2025-05-20 Simon Schindler , Elias Steffen Reich , Saverio Messineo , Simon Hoher , Stefan Huber
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