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Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

We investigate the utility of pretraining by contrastive self supervised learning on both natural-scene and medical imaging datasets when the unlabeled dataset size is small, or when the diversity within the unlabeled set does not lead to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Ozan Ciga , Tony Xu , Anne L. Martel

Self-supervised learning holds the promise of eliminating the need for manual data annotation, enabling models to scale effortlessly to massive datasets and larger architectures. By not being tailored to specific tasks or domains, this…

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

Machine Learning · Computer Science 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

There exist numerous diagnostic tasks in pathology. Conventional computational pathology formulates and tackles them as independent and individual image classification problems, thereby resulting in computational inefficiency and high…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Boram Song , Seoung Wan Chae , Jin Tae Kwak

Foundation vision encoders such as CLIP and DINOv2, trained on web-scale data, exhibit strong transfer performance across tasks and datasets. However, medical imaging foundation models remain constrained by smaller datasets, limiting our…

Determining early-stage prognostic markers and stratifying patients for effective treatment are two key challenges for improving outcomes for melanoma patients. Previous studies have used tumour transcriptome data to stratify patients into…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Lucy Godson , Navid Alemi , Jeremie Nsengimana , Graham P. Cook , Emily L. Clarke , Darren Treanor , D. Timothy Bishop , Julia Newton-Bishop , Ali Gooya

Obtaining large pre-trained models that can be fine-tuned to new tasks with limited annotated samples has remained an open challenge for medical imaging data. While pre-trained deep networks on ImageNet and vision-language foundation models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Duy M. H. Nguyen , Hoang Nguyen , Nghiem T. Diep , Tan N. Pham , Tri Cao , Binh T. Nguyen , Paul Swoboda , Nhat Ho , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag , Mathias Niepert

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Large amounts of digitized histopathological data display a promising future for developing pathological foundation models via self-supervised learning methods. Foundation models pretrained with these methods serve as a good basis for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Shengyi Hua , Fang Yan , Tianle Shen , Lei Ma , Xiaofan Zhang

Human anatomy is the foundation of medical imaging and boasts one striking characteristic: its hierarchy in nature, exhibiting two intrinsic properties: (1) locality: each anatomical structure is morphologically distinct from the others;…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Mohammad Reza Hosseinzadeh Taher , Michael B. Gotway , Jianming Liang

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Task-specific microscopy datasets are often too small to train deep learning models that learn robust feature representations. Self-supervised learning (SSL) can mitigate this by pretraining on large unlabeled datasets, but it remains…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Ben Isselmann , Dilara Göksu , Andreas Weinmann

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Self-supervised learning has proven to be an effective way to learn representations in domains where annotated labels are scarce, such as medical imaging. A widely adopted framework for this purpose is contrastive learning and it has been…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Hugo Figueiras , Helena Aidos , Nuno Cruz Garcia
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