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Poor tissue visualization and quantitative accuracy in CBCT is a major barrier in expanding the role of CBCT imaging from target localization to quantitative treatment monitoring and plan adaptations in radiation therapy sessions. To…

Medical Physics · Physics 2023-08-21 Farhang Bayat , Dan Ruan , Moyed Miften , Cem Altunbas

Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

Background: Dual-energy (DE) imaging techniques in cone-beam computed tomography (CBCT) have potential clinical applications, including material quantification and improved tissue visualization. However, the performance of DE CBCT is…

Medical Physics · Physics 2023-06-26 Cem Altunbas

Purpose: We have been investigating 2D antiscatter grids (2D ASG) to reduce scatter fluence and improve image quality in cone beam computed tomography (CBCT). In this work, two different aspects of 2D ASGs, their scatter rejection and…

Medical Physics · Physics 2021-06-09 Yeonok Park , Timur Alexeev , Brian Miller , Moyed Miften , Cem Altunbas

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

Medical Physics · Physics 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

The concept of using kilovoltage (kV) and megavoltage (MV) beams concurrently has potential applications in cone beam computed tomography (CBCT) guided radiation therapy, such as single breath hold scans, metal artifact reduction, and…

Medical Physics · Physics 2022-08-24 Farhang Bayat , Mohamed Elsayed Eldib , Brian Kavanagh , Moyed Miften , Cem Altunbas

Recently, X-ray imaging dose from computed tomography (CT) or cone beam CT (CBCT) scans has become a serious concern. Patient-specific imaging dose calculation has been proposed for the purpose of dose management. While Monte Carlo (MC)…

Medical Physics · Physics 2015-05-30 Xun Jia , Hao Yan , Xuejun Gu , Steve B. Jiang

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

Objective: The aim of this study is to validate the effectiveness of an energy-modulated scatter correction method in suppressing scatter in photon-counting detector (PCD)-based cone beam CT (CBCT) imaging. Approach: The scatter correction…

Medical Physics · Physics 2024-12-18 Xin Zhang , Ting Su , Jiongtao Zhu , Hairong Zheng , Dong Liang , Yongshuai Ge

Cone-beam computed tomography (CBCT) systems, with their flexibility, present a promising avenue for direct point-of-care medical imaging, particularly in critical scenarios such as acute stroke assessment. However, the integration of CBCT…

Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung,…

Daily or weekly cone-beam computed tomography (CBCT) is employed in image-guided radiotherapy (IGRT) for precise patient alignment. However, its clinical utility in quantitative tasks is hindered by severe artifacts and inaccurate Hounsfeld…

Medical Physics · Physics 2026-03-09 Junbo Peng , Huiqiao Xie , Tonghe Wang , Xiangyang Tang , Xiaofeng Yang

Purpose: Estimation of patient-specific organ doses is required for more comprehensive dose metrics, such as effective dose. Currently, available methods are performed retrospectively using the CT images themselves, which can only be done…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Abdullah-Al-Zubaer Imran , Sen Wang , Debashish Pal , Sandeep Dutta , Bhavik Patel , Evan Zucker , Adam Wang

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

Medical Physics · Physics 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Adaptive radiotherapy is a growing field of study in cancer treatment due to it's objective in sparing healthy tissue. The standard of care in several institutions includes longitudinal cone-beam computed tomography (CBCT) acquisitions to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 William Trung Le , Chulmin Bang , Philippine Cordelle , Daniel Markel , Phuc Felix Nguyen-Tan , Houda Bahig , Samuel Kadoury

Cone-beam computed tomography (CBCT) is a valuable imaging method in dental diagnostics that provides information not available in traditional 2D imaging. However, interpretation of CBCT images is a time-consuming process that requires a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Adel Zakirov , Matvey Ezhov , Maxim Gusarev , Vladimir Alexandrovsky , Evgeny Shumilov
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