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Low-dose CT imaging requires reconstruction from noisy indirect measurements which can be defined as an ill-posed linear inverse problem. In addition to conventional FBP method in CT imaging, recent compressed sensing based methods exploit…
Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…
Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…
Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…
Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…
Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…
Computed tomography (CT) is widely utilized in clinical settings because it delivers detailed 3D images of the human body. However, performing CT scans is not always feasible due to radiation exposure and limitations in certain surgical…
Diffusion models have emerged as powerful priors for solving inverse problems in computed tomography (CT). In certain applications, such as neutron CT, it can be expensive to collect large amounts of measurements even for a single scan,…
Cone-beam X-ray Computed Tomography (XCT) with large detectors and corresponding large-scale 3D reconstruction plays a pivotal role in micron-scale characterization of materials and parts across various industries. In this work, we present…
Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…
Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…
Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…
Magnetic Resonance Imaging (MRI) is a powerful imaging technique widely used for visualizing structures within the human body and in other fields such as plant sciences. However, there is a demand to develop fast 3D-MRI reconstruction…
X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…
The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…
Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…
Image reconstruction of low-count positron emission tomography (PET) data is challenging. Kernel methods address the challenge by incorporating image prior information in the forward model of iterative PET image reconstruction. The…
Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…
Cardiac computed tomography (CT) has emerged as a major imaging modality for the diagnosis and monitoring of cardiovascular diseases. High temporal resolution is essential to ensure diagnostic accuracy. Limited-angle data acquisition can…
X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…