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Related papers: DrugCLIP: Contrastive Protein-Molecule Representat…

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Contrastive Language-Image Pre-training (CLIP) has made a remarkable breakthrough in open-vocabulary zero-shot image recognition. Many recent studies leverage the pre-trained CLIP models for image-level classification and manipulation. In…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Chong Zhou , Chen Change Loy , Bo Dai

Despite profound successes, contrastive representation learning relies on carefully designed data augmentations using domain specific knowledge. This challenge is magnified in natural language processing where no general rules exist for…

Computation and Language · Computer Science 2022-02-28 Dejiao Zhang , Wei Xiao , Henghui Zhu , Xiaofei Ma , Andrew O. Arnold

As machine learning evolves, domain generalization (DG) and domain adaptation (DA) have become crucial for enhancing model robustness across diverse environments. Contrastive Language-Image Pretraining (CLIP) plays a significant role in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Jindong Li , Yongguang Li , Yali Fu , Jiahong Liu , Yixin Liu , Menglin Yang , Irwin King

In this paper, we introduce DetailCLIP: A Detail-Oriented CLIP to address the limitations of contrastive learning-based vision-language models, particularly CLIP, in handling detail-oriented and fine-grained tasks like segmentation. While…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Amin Karimi Monsefi , Kishore Prakash Sailaja , Ali Alilooee , Ser-Nam Lim , Rajiv Ramnath

With the rapid growth of video data, text-video retrieval technology has become increasingly important in numerous application scenarios such as recommendation and search. Early text-video retrieval methods suffer from two critical…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiaao Yu , Mingjie Han , Tao Gong , Jian Zhang , Man Lan

The binding between proteins and ligands plays a crucial role in the realm of drug discovery. Previous deep learning approaches have shown promising results over traditional computationally intensive methods, but resulting in poor…

Biomolecules · Quantitative Biology 2023-11-29 Shikun Feng , Minghao Li , Yinjun Jia , Weiying Ma , Yanyan Lan

Recently, contrastive self-supervised learning has become a key component for learning visual representations across many computer vision tasks and benchmarks. However, contrastive learning in the context of domain adaptation remains…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Mamatha Thota , Georgios Leontidis

Density ratio estimation is a core concept in statistical machine learning because it provides a unified mechanism for tasks such as importance weighting, divergence estimation, and likelihood-free inference, but its potential in vision and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Fumiya Uchiyama , Rintaro Yanagi , Shohei Taniguchi , Shota Takashiro , Masahiro Suzuki , Hirokatsu Kataoka , Yusuke Iwasawa , Yutaka Matsuo

Despite that deep learning (DL) methods have presented tremendous potential in many medical image analysis tasks, the practical applications of medical DL models are limited due to the lack of enough data samples with manual annotations. By…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Zhiyang Liu , Dong Yang , Minghao Zhang , Hanyu Sun , Hong Wu , Huiying Wang , Wen Shen , Chao Chai , Shuang Xia

Precision medicine fundamentally aims to establish causality between dysregulated biochemical mechanisms and cancer subtypes. Omics-based cancer subtyping has emerged as a revolutionary approach, as different level of omics records the…

Genomics · Quantitative Biology 2023-08-25 Ziwei Yang , Zheng Chen , Yasuko Matsubara , Yasushi Sakurai

Multimodal deep learning holds promise for improving clinical prediction by integrating diverse patient data, including text, imaging, time-series, and structured demographics. Contrastive learning facilitates this integration by producing…

Machine Learning · Computer Science 2025-07-08 Michal Golovanevsky , Pranav Mahableshwarkar , Carsten Eickhoff , Ritambhara Singh

Existing computer vision research in artwork struggles with artwork's fine-grained attributes recognition and lack of curated annotated datasets due to their costly creation. To the best of our knowledge, we are one of the first methods to…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Marcos V. Conde , Kerem Turgutlu

Recent years have seen a rapid growth of utilizing graph neural networks (GNNs) in the biomedical domain for tackling drug-related problems. However, like any other deep architectures, GNNs are data hungry. While requiring labels in real…

Biological Physics · Physics 2022-05-03 Mengying Sun , Jing Xing , Huijun Wang , Bin Chen , Jiayu Zhou

Fonts convey different impressions to readers. These impressions often come from the font shapes. However, the correlation between fonts and their impression is weak and unstable because impressions are subjective. To capture such weak and…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yugo Kubota , Daichi Haraguchi , Seiichi Uchida

Contrastive learning is a well-established paradigm in representation learning. The standard framework of contrastive learning minimizes the distance between "similar" instances and maximizes the distance between dissimilar ones in the…

Machine Learning · Computer Science 2025-02-06 Naghmeh Ghanooni , Barbod Pajoum , Harshit Rawal , Sophie Fellenz , Vo Nguyen Le Duy , Marius Kloft

Unsupervised domain adaptation which aims to adapt models trained on a labeled source domain to a completely unlabeled target domain has attracted much attention in recent years. While many domain adaptation techniques have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Aadarsh Sahoo , Rutav Shah , Rameswar Panda , Kate Saenko , Abir Das

We propose a novel unsupervised backlit image enhancement method, abbreviated as CLIP-LIT, by exploring the potential of Contrastive Language-Image Pre-Training (CLIP) for pixel-level image enhancement. We show that the open-world CLIP…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zhexin Liang , Chongyi Li , Shangchen Zhou , Ruicheng Feng , Chen Change Loy

The recent advancements in Generative Adversarial Networks (GANs) and the emergence of Diffusion models have significantly streamlined the production of highly realistic and widely accessible synthetic content. As a result, there is a…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Sohail Ahmed Khan , Duc-Tien Dang-Nguyen

Large-scale multi-modal contrastive pre-training has demonstrated great utility to learn transferable features for a range of downstream tasks by mapping multiple modalities into a shared embedding space. Typically, this has employed…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Haoxuan You , Luowei Zhou , Bin Xiao , Noel Codella , Yu Cheng , Ruochen Xu , Shih-Fu Chang , Lu Yuan

Contrastive learning has gained significant attention in short text clustering, yet it has an inherent drawback of mistakenly identifying samples from the same category as negatives and then separating them in the feature space (false…

Machine Learning · Computer Science 2026-03-16 Zhihao Yao
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