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Neural codes are binary codes that are used for information processing and representation in the brain. In previous work, we have shown how an algebraic structure, called the {\it neural ring}, can be used to efficiently encode geometric…

Neurons and Cognition · Quantitative Biology 2019-02-14 Carina Curto , Nora Youngs

How does the brain encode spatial structure? One way is through hippocampal neurons called place cells, which become associated to convex regions of space known as their receptive fields: each place cell fires at a high rate precisely when…

Neurons and Cognition · Quantitative Biology 2016-12-20 Caitlin Lienkaemper , Anne Shiu , Zev Woodstock

We investigate combinatorial, topological and algebraic properties of certain classes of neural codes. We look into a conjecture that states if the minimal \textit{open convex} embedding dimension of a neural code is two then its minimal…

Geometric Topology · Mathematics 2023-09-21 Neha Gupta , Suhith K N

Much work has been done to identify which binary codes can be represented by collections of open convex or closed convex sets. While not all binary codes can be realized by such sets, here we prove that every binary code can be realized by…

Combinatorics · Mathematics 2018-04-30 Megan K. Franke , Samuel Muthiah

A neural code on $ n $ neurons is a collection of subsets of the set $ [n]=\{1,2,\dots,n\} $. Curto et al. \cite{curto2013neural} associated a ring $\mathcal{R}_{\mathcal{C}}$ (neural ring) to a neural code $\mathcal{C}$. A special class of…

Category Theory · Mathematics 2024-03-27 Neha Gupta , Suhith K N

Given an intersection pattern of arbitrary sets in Euclidean space, is there an arrangement of convex open sets in Euclidean space that exhibits the same intersections? This question is combinatorial and topological in nature, but is…

Combinatorics · Mathematics 2019-02-22 Aaron Chen , Florian Frick , Anne Shiu

We introduce new geometric and combinatorial criteria that preclude a neural code from being convex, and use them to tackle the classification problem for codes on six neurons. Along the way, we give the first example of a code that is…

Combinatorics · Mathematics 2023-02-16 Laura Matusevich , Alexander Ruys de Perez , Anne Shiu

Neural codes serve as a language for neurons in the brain. Convex codes, which arise from the pattern of intersections of convex sets in Euclidean space, are of particular relevance to neuroscience. Not every code is convex, however, and…

Combinatorics · Mathematics 2017-05-31 Joshua Cruz , Chad Giusti , Vladimir Itskov , Bill Kronholm

The neural ideal of a binary code $\mathbb{C} \subseteq \mathbb{F}_2^n$ is an ideal in $\mathbb{F}_2[x_1,\ldots, x_n]$ closely related to the vanishing ideal of $\mathbb{C}$. The neural ideal, first introduced by Curto et al, provides an…

Commutative Algebra · Mathematics 2019-08-26 R. Amzi Jeffs , Mohamed Omar , Nora Youngs

For a neural code $\mathcal{C}\subseteq\mathbb{F}_2^n$, polarizing the canonical form generators of the neural ideal $J_{\mathcal{C}}$ yields a squarefree monomial ideal $\mathcal{P}(J_{\mathcal{C}})\subset k[x_1,\dots,x_n,y_1,\dots,y_n]$,…

Commutative Algebra · Mathematics 2026-02-20 Selvi Kara , Ellie Lew

Neural codes allow the brain to represent, process, and store information about the world. Combinatorial codes, comprised of binary patterns of neural activity, encode information via the collective behavior of populations of neurons. A…

Neurons and Cognition · Quantitative Biology 2016-12-22 Carina Curto , Elizabeth Gross , Jack Jeffries , Katherine Morrison , Mohamed Omar , Zvi Rosen , Anne Shiu , Nora Youngs

Neural codes, represented as collections of binary strings called codewords, are used to encode neural activity. A code is called convex if its codewords are represented as an arrangement of convex open sets in Euclidean space. Previous…

Combinatorics · Mathematics 2022-08-10 Katherine Johnston , Anne Shiu , Clare Spinner

Neural codes are lists of subsets of neurons that fire together. Of particular interest are neurons called place cells, which fire when an animal is in specific, usually convex regions in space. A fundamental question, therefore, is to…

Combinatorics · Mathematics 2021-04-05 Brianna Gambacini , R. Amzi Jeffs , Sam Macdonald , Anne Shiu

Place cells are neurons that act as biological position sensors, associated with and firing in response to regions of an environment to situate an organism in space. These associations are recorded in (combinatorial) neural codes,…

Combinatorics · Mathematics 2025-10-24 Saber Ahmed , Natasha Crepeau , Gisel Flores , Osiano Isekenegbe , Deanna Perez , Anne Shiu

Neurons in the brain represent external stimuli via neural codes. These codes often arise from stimulus-response maps, associating to each neuron a convex receptive field. An important problem confronted by the brain is to infer properties…

Neurons and Cognition · Quantitative Biology 2014-09-10 Nora Youngs

A combinatorial neural code is a subset of the power set $2^{[n]}$ on $[n]=\{1,\dots, n\}$, in which each $1\leq i\leq n$ represents a neuron and each element (codeword) represents the co-firing event of some neurons. Consider a space…

Combinatorics · Mathematics 2025-12-05 R. Amzi Jeffs , Trong-Thuc Trang

Based on the theoretical neuroscience, G. Cotardo and A. Ravagnavi in \cite{CR} introduced a kind of asymmetric binary codes called combinatorial neural codes (CN codes for short), with a "matched metric" $\delta_{r}$ called asymmetric…

Information Theory · Computer Science 2021-12-16 Aixian Zhang , Xiaoyan Jin , Keqin Feng

Error-correcting codes that admit local decoding and correcting algorithms have been the focus of much recent research due to their numerous theoretical and practical applications. An important goal is to obtain the best possible tradeoffs…

Data Structures and Algorithms · Computer Science 2018-09-19 Jeremiah Blocki , Venkata Gandikota , Elena Grigorescu , Samson Zhou

Let $\xx= x_1,\ldots,x_r$ denote a system of elements of a commutative ring $R$. For an $R$-module $M$ we investigate when $\xx$ is $M$-pro-regular resp. $M$-weakly pro-regular as generalizations of $M$-regular sequences. This is done in…

Commutative Algebra · Mathematics 2024-04-23 Peter Schenzel

A convex code is a binary code generated by the pattern of intersections of a collection of open convex sets in some Euclidean space. Convex codes are relevant to neuroscience as they arise from the activity of neurons that have convex…

Neurons and Cognition · Quantitative Biology 2018-07-10 Carina Curto , Elizabeth Gross , Jack Jeffries , Katherine Morrison , Zvi Rosen , Anne Shiu , Nora Youngs
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