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Graphical model estimation from multi-omics data requires a balance between statistical estimation performance and computational scalability. We introduce a novel pseudolikelihood-based graphical model framework that reparameterizes the…

Machine Learning · Statistics 2025-09-23 Sungdong Lee , Joshua Bang , Youngrae Kim , Hyungwon Choi , Sang-Yun Oh , Joong-Ho Won

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

Medical Physics · Physics 2025-10-22 Haotian Feng , Ke Sheng

In this chapter we illustrate the use of some Machine Learning techniques in the context of omics data. More precisely, we review and evaluate the use of Random Forest and Penalized Multinomial Logistic Regression for integrative analysis…

Genomics · Quantitative Biology 2024-02-09 Aida Calviño , Almudena Moreno-Ribera , Silvia Pineda

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Small data learning problems are characterized by a significant discrepancy between the limited amount of response variable observations and the large feature space dimension. In this setting, the common learning tools struggle to identify…

Machine Learning · Computer Science 2023-10-31 Edoardo Vecchi , Davide Bassetti , Fabio Graziato , Lukas Pospisil , Illia Horenko

Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

Causal effect estimation is a critical task in statistical learning that aims to find the causal effect on subjects by identifying causal links between a number of predictor (or, explanatory) variables and the outcome of a treatment. In a…

Methodology · Statistics 2024-11-26 Tathagata Basu , Matthias C. M. Troffaes

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Lung cancer is one of the deadliest diseases and the leading cause of illness and death. Since lung cancer cannot predicted at premature stage, it able to only be discovered more broadly once it has spread to other lung parts. The risk…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 V S Priya Sumitha , V. Keerthika , A. Geetha

A significant challenge in solid tumors is reliably distinguishing confounding pathologies from malignant neoplasms on routine imaging. While radiomics methods seek surrogate markers of lesion heterogeneity on CT/MRI, many aggregate…

Causal discovery methods can identify valid adjustment sets for causal effect estimation for a pair of target variables, even when the underlying causal graph is unknown. Global causal discovery methods focus on learning the whole causal…

Machine Learning · Statistics 2026-04-01 Mátyás Schubert , Tom Claassen , Sara Magliacane

Algorithm selection (AS) deals with selecting an algorithm from a fixed set of candidate algorithms most suitable for a specific instance of an algorithmic problem, e.g., choosing solvers for SAT problems. Benchmark suites for AS usually…

Machine Learning · Computer Science 2020-10-23 Alexander Tornede , Marcel Wever , Eyke Hüllermeier

Nowadays, Breast cancer has risen to become one of the most prominent causes of death in recent years. Among all malignancies, this is the most frequent and the major cause of death for women globally. Manually diagnosing this disease…

Machine Learning · Computer Science 2022-07-01 Taminul Islam , Arindom Kundu , Nazmul Islam Khan , Choyon Chandra Bonik , Flora Akter , Md Jihadul Islam

The main objective of this work is to accelerate the Maximum-Likelihood (ML) estimation procedure in radio interferometric calibration. We introduce the OS-LS and the OS-SAGE radio interferometric calibration methods, as a combination of…

Instrumentation and Methods for Astrophysics · Physics 2015-06-16 S. Kazemi , S. Yatawatta , S. Zaroubi

Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Objective: Radiomics-driven Computer Aided Diagnosis (CAD) has shown considerable promise in recent years as a potential tool for improving clinical decision support in medical oncology, particularly those based around the concept of…

Artificial Intelligence · Computer Science 2017-10-31 Devinder Kumar , Graham W. Taylor , Alexander Wong

3D computer-assisted corrective osteotomy has become the state-of-the-art for surgical treatment of complex bone deformities. Despite available technologies, the automatic generation of clinically acceptable, ready-to-use preoperative…

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

Quantitative Methods · Quantitative Biology 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Rushabh Patel