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On-chip scalable integration represents a major challenge for practical quantum devices. One particular challenge is to implement on-chip optical readout of spins in diamond. This readout requires simultaneous application of optical and…

Millimetre-wave observations represent an important tool for Cosmology studies. The Line Intensity Mapping (LIM) technique has been proposed to map in three dimensions the specific intensity due to line (e.g. [CII], CO) emission, for…

Instrumentation and Methods for Astrophysics · Physics 2023-08-29 Usasi Chowdhury , Florence Levy-Bertrand , Martino Calvo , Johannes Goupy , Alessandro Monfardini

We show that high-resolution NMR can reach picomole sensitivity for micromolar concentrations of analyte by combining parahydrogen induced hyperpolarisation (PHIP)with a high-sensitivity transmission line micro-detector. The para-enriched…

Chemical Physics · Physics 2019-05-20 James Eills , William Hale , Manvendra Sharma , Matheus Rossetto , Malcolm H. Levitt , Marcel Utz

We present and characterize a 2-D imaging spectrometer based on a virtually-imaged phased array (VIPA) disperser for rapid, high-resolution molecular detection using mid-infrared (MIR) frequency combs at 3.1 and 3.8 \mu m. We demonstrate…

Chiral spectroscopy is a powerful technique that enables to identify the chirality of matter through optical means. So far, experiments to check the chirality of matter or nanostructures have been carried out using free-space propagating…

Optics · Physics 2019-11-26 J. Enrique Vázquez-Lozano , Alejandro Martínez

Highly sensitive photodetectors with single photon level detection is one of the key components to a range of emerging technologies, in particular the ever-growing field of optical communication, remote sensing, and quantum computing.…

Optics · Physics 2021-09-16 Yi Zhu , Vidur Raj , Ziyuan Li , Hark Hoe Tan , Chennupati Jagadish , Lan Fu

IR spectroscopy such as Fourier transform infrared spectroscopy (FTIR) are widely used for the investigation of structure and the quantitative determination of substances in the fields of chemistry, physics, biology, medicine, and…

Chiral molecule sensing is currently performed using chromatography, electrophoresis, enzymatic-assays, mass spectrometry, and chiroptical sensing techniques. Currently polarimetry is the only method having in-vivo sensing capabilities,…

Medical Physics · Physics 2024-01-22 Swathi Padmanabhan , Jaya Prakash

Microscopy with extreme ultraviolet (EUV) radiation holds promise for high-resolution imaging with excellent material contrast, due to the short wavelength and numerous element-specific absorption edges available in this spectral range. At…

Label-free detection techniques for single particles and molecules play an important role in basic science, disease diagnostics, and nanomaterial investigations. While traditional fluorescence-based methods offer powerful tools for single…

Optics · Physics 2024-08-20 Shuang Hao , Sartanee Suebka , Judith Su

In this article, we describe the MIRI Imager module (MIRIM), which provides broad-band imaging in the 5 - 27 microns wavelength range for the James Webb Space Telescope. The imager has a 0"11 pixel scale and a total unobstructed view of…

Label-free optical imaging is valuable in biology and medicine with its non-destructive property and reduced optical and chemical damages. Quantitative phase (QPI) and molecular vibrational imaging (MVI) are the two most successful…

Super-resolution microscopy in the visible is an established powerful tool in several disciplines. In the infrared (IR) spectral range, however, no comparable schemes have been demonstrated to date. In this work, we experimentally…

The microwave response of high quality niobium films in a perpendicular static magnetic field has been investigated. The complex frequency shift was measured up to the upper critical fields. The data have been analyzed by the effective…

Superconductivity · Physics 2007-05-23 D. Janjusevic , M. S. Grbic , M. Pozek , A. Dulcic , D. Paar , B. Nebendahl , T. Wagner

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain…

Physics Education · Physics 2019-07-24 Stephane Perrin , Keshia Badu , Paul Montgomery , Sylvain Lecler

Current technologies for infrared detection have been based on epitaxially grown semiconductors. Here we review some of the recent developments relative to colloidal nanocrystals and their use as building blocks for the design of low-cost…

Minfrared spectroscopic imaging (MIRSI) is an emerging class of label-free, biochemically quantitative technologies targeting digital histopathology. Conventional histopathology relies on chemical stains that alter tissue color. This…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Mahsa Lotfollahi , Nguyen Tran , Sebastian Berisha , Chalapathi Gajjela , Zhu Han , David Mayerich , Rohith Reddy

Microwave photonic (MWP) transversal signal processors offer a compelling solution for realizing versatile high-speed information processing by combining the advantages of reconfigurable electrical digital signal processing and…

Signal Processing · Electrical Eng. & Systems 2023-09-15 Yang Sun , Jiayang Wu , Yang Li , Xingyuan Xu , Guanghui Ren , Mengxi Tan , Sai Tak Chu , Brent E. Little , Roberto Morandotti , Arnan Mitchell , David J. Moss

Spatial frequency filtering is a fundamental enabler of information processing methods in biological and technical imaging. Most filtering methods, however, require either bulky and expensive optical equipment or some degree of…