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Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, offer substantial advantages for in vivo imaging, owing to their deep tissue penetration and minimal background autofluorescence. Nanoparticles incorporating…

Medical Physics · Physics 2024-11-07 Michael Adeniyi

This paper presents for the first time an innovative instrument called an inverted scanning microwave microscope (iSMM), which is capable of noninvasive and label-free imaging and characterization of intracellular structures of a live cell…

Hierarchical polymer structures such as pNIPAM microgels have been extensively studied for their ability to undergo significant structural and physical transformations that can be controlled by external stimuli such as temperature, pH or…

Soft Condensed Matter · Physics 2017-08-25 Gaurasundar Marc Conley , Söfi Nojd , Marco Braibanti , Peter Schurtenberger , Frank Scheffold

The longwave infrared (LWIR) region of the spectrum spans 8 to 14 {\mu}m and enables high-performance sensing and imaging for detection, ranging, and monitoring. Chip-scale integrated LWIR photonics has enormous potential for real-time…

Optics · Physics 2021-11-02 Dingding Ren , Chao Dong , David Burghoff

Shortwave infrared (SWIR) has various applications, including night vision, remote sensing, and medical imaging. SWIR organic photodetectors (OPDs) offer advantages such as flexibility, cost-effectiveness, and tunable properties, however,…

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Imaging in a broad light-intensity regime with a high signal-to-noise ratio is a key capability in fields as diverse as Quantum Metrology and Astronomy. Achieving high signal-to-noise ratios in quantum imaging leads to surpassing the…

Instrumentation and Detectors · Physics 2023-01-27 Q. Pears Stefano , A. G. Magnoni , J. Estrada , C. Iemmi , D. Rodrigues , J. Tiffenberg

Photothermal-Induced Resonance (PTIR) spectroscopy and imaging with infrared light has seen increasing application in molecular spectroscopy of biological samples. The appeal of the technique lies in its capability to provide information…

Quantitative Methods · Quantitative Biology 2019-11-19 Luca Quaroni

Ovarian cancer detection has traditionally relied on a multi-step process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several…

Mid-infrared photothermal microscopy is a highly promising imaging technique that enables spatially resolved vibrational fingerprinting. The combination of infrared induced heating with optical readout at visible wavelengths provides…

Optics · Physics 2025-08-05 Dennis van de Lockand , Daan Wolters , Matz Liebel

Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…

High resolution and fast detection of molecular vibrational absorption is important for organic synthesis, pharmaceutical process and environmental monitoring, and is enabled by mid-infrared (mid-IR) laser frequency combs via dual-comb…

Conventional bright-field (BF) cytology of thyroid fine-needle aspiration biopsy (FNAB) suffers from staining variability and limited subcellular contrast. Here, we present a refractive index-correlated pseudocoloring (RICP) framework that…

Scattering-type scanning near-field optical microscopy (s-SNOM), and its derivate, Fourier transform infrared nanospectroscopy (nano-FTIR) are emerging techniques for infrared (IR) nanoimaging and spectroscopy with applications in diverse…

Hyperspectral imaging in the mid-infrared (MIR) spectral range provides unique molecular specificity by probing fundamental vibrational modes of molecular bonds, making it highly valuable for biomedical and biochemical applications.…

Sensitive mid-infrared (MIR) spectroscopy plays an indispensable role in various photon-starved conditions. However, the detection sensitivity of conventional MIR spectrometers is severely limited by excessive noises of the involved…

Near-infrared (NIR) hyperspectral imaging is widely used to reveal morphological and chemical information. However, conventional spectral imagers usually rely on costly focal plane arrays and suffer from data redundancy and inefficiencies…

Optics · Physics 2026-05-26 Ben Sun , Kun Huang , Zhibin Zhao , Beibei Dong , Jianan Fang , Heping Zeng

We demonstrate a thermal infrared (IR) detector based on an ultra-high-quality-factor (Q) whispering-gallery-mode (WGM) microtoroidal silica resonator, and investigate its performance to detect IR radiation at 10 micron wavelength. The…

Optics · Physics 2015-06-19 Jiangang Zhu , Sahin Kaya Ozdemir , Lan Yang

The enhancement of the inherently weak optical activity of solvated molecules by superchiral fields, crucial for detecting their chirality, is a research frontier of photonics and the basis of novel chiroptical detection schemes. Here, we…

Microwave photonic (MWP) filters are essential components in microwave systems due to their wide bandwidth, low loss, and immunity to electromagnetic interference. A sharp transition band is critical for precise spectral shaping and…

Optics · Physics 2026-01-09 David J. Moss
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