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Continuous cardiovascular monitoring is essential for managing circulatory health and disease, yet most wearable sensors are constrained by reliance on electrical transduction and built-in electronics. We present a circuit-free, wholly…
Mohs micrographic surgery (MMS) is a precise oncological technique where layers of tissue are resected and examined with intraoperative histopathology to minimize the removal of normal tissue while completely excising the cancer. To achieve…
Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective, causing delays in diagnosis. Digital pathology plays a…
Photoacoustic imaging has emerged as a powerful, non-invasive modality for various biomedical applications. Conventional photoacoustic systems require contact-based ultrasound detection and expensive and bulky high-power lasers for the…
Many essential cellular functions depend on the viscoelastic properties of the cytoplasm. While techniques such as optical tweezers and atomic force microscopy can measure these properties, their reliance on localized probes prevents…
Using the complementary wave- and particle-like natures of photons, it is possible to make ``interaction-free'' measurements where the presence of an object can be determined with no photons being absorbed. We investigated several…
Circulatory system abnormalities might be an indicator of diseases or tissue damage. Early detection of vascular abnormalities might have an important role during treatment and also raise the patient's awarenes. Current detection methods…
Optical imaging below the limit of light diffraction offers an unprecedented opportunity to study outlook, organization, interactions or in-situ functioning of sub-micrometer, highly transparent objects such as subcellular structures in…
Imaging-based, non-contact measurement of physiology (including imaging photoplethysmography and imaging ballistocardiography) is a growing field of research. There are several strengths of imaging methods that make them attractive. They…
Cardiovascular monitoring is important to prevent diseases from progressing. The jugular venous pulse (JVP) waveform offers important clinical information about cardiac health, but is not routinely examined due to its invasive…
The lensless endoscope (LE) is a promising device to acquire in vivo images at a cellular scale. The tiny size of the probe enables a deep exploration of the tissues. Lensless endoscopy with a multicore fiber (MCF) commonly uses a spatial…
Numerous real-world applications have been driven by the recent algorithmic advancement of artificial intelligence (AI). Healthcare is no exception and AI technologies have great potential to revolutionize the industry. Non-contact…
Continuous monitoring of vital signs is of paramount importance. These critical physiological parameters play a crucial role in the early detection of conditions that affect the well-being of a patient. However, conventional contact-based…
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic…
Lipid droplets (LDs), once considered mere storage depots for lipids, have gained recognition for their intricate roles in cellular processes, including metabolism, membrane trafficking, and disease states like obesity and cancer. This…
Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…
Monitoring of cardiovascular activity is highly desired and can enable novel applications in diagnosing potential cardiovascular diseases and maintaining an individual's well-being. Currently, such vital signs are measured using intrusive…
Vibrational microscopy provides label-free, bond-selective chemical contrast by detecting molecular vibrations, making it invaluable for biomedical research. While conventional methods rely on the direct detection of Raman scattering or…
Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that is becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature…
Blood oxygen saturation (SpO2) is a crucial vital sign routinely monitored in medical settings. Traditional methods require dedicated contact sensors, limiting accessibility and comfort. This study presents a deep learning framework for…