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Patients who are at clinical high risk (CHR) for schizophrenia need close monitoring of their symptoms to inform appropriate treatments. The Brief Psychiatric Rating Scale (BPRS) is a validated, commonly used research tool for measuring…

Computation and Language · Computer Science 2025-08-15 Andrew X. Chen , Guillermo Horga , Sean Escola

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and…

Computation and Language · Computer Science 2024-06-06 Xiangru Tang , Anni Zou , Zhuosheng Zhang , Ziming Li , Yilun Zhao , Xingyao Zhang , Arman Cohan , Mark Gerstein

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Mental health in children and adolescents has been steadily deteriorating over the past few years. The recent advent of Large Language Models (LLMs) offers much hope for cost and time efficient scaling of monitoring and intervention, yet…

Computation and Language · Computer Science 2024-04-29 Isabelle Lorge , Dan W. Joyce , Andrey Kormilitzin

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

Adherence to healthy diets reduces chronic illness risk, yet rates remain low. Large Language Models (LLMs) are increasingly used for health communication but often struggle to engage individuals with ambivalent intentions at a pivotal…

Human-Computer Interaction · Computer Science 2025-11-05 Michelle Bak , Kexin Quan , Tre Tomaszewski , Jessie Chin

Existing stress-management tools fail to account for the timing and contextual specificity of students' daily lives, often providing static or misaligned support. Digital calendars contain rich, personal indicators of upcoming…

Human-Computer Interaction · Computer Science 2025-06-02 Pranav Rao , Maryam Taj , Alex Mariakakis , Joseph Jay Williams , Ananya Bhattacharjee

Limited access to mental healthcare resources hinders timely depression diagnosis, leading to detrimental outcomes. Social media platforms present a valuable data source for early detection, yet this task faces two significant challenges:…

Computation and Language · Computer Science 2025-10-10 Xiaochong Lan , Zhiguang Han , Yiming Cheng , Li Sheng , Jie Feng , Chen Gao , Yong Li

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

Large Language Models (LLMs) offer promising opportunities to support mental healthcare workflows, yet they often lack the structured clinical reasoning needed for reliable diagnosis and may struggle to provide the emotionally attuned…

Artificial Intelligence · Computer Science 2026-04-20 Yuqi Wu , Guangya Wan , Jingjing Li , Shengming Zhao , Lingfeng Ma , Tianyi Ye , Ion Pop , Yanbo Zhang , Jie Chen

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

Rich and context-aware activity logs facilitate user behavior analysis and health monitoring, making them a key research focus in ubiquitous computing. The remarkable semantic understanding and generation capabilities of Large Language…

Artificial Intelligence · Computer Science 2025-07-21 Ye Tian , Xiaoyuan Ren , Zihao Wang , Onat Gungor , Xiaofan Yu , Tajana Rosing

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

Mental health remains a major public health concern, while access to timely psychological support is often limited. AI-based dialogue systems have emerged as promising tools to address these barriers, and recent advances in large language…

Computers and Society · Computer Science 2026-03-16 Daeun Lee , Dongje Yoo , Migyeong Yang , Jihyun An , Christine B. Cha , Jinyoung Han

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

Mental health assessments are of central importance to individuals' well-being. Conventional assessment methodologies predominantly depend on clinical interviews and standardised self-report questionnaires. Nevertheless, the efficacy of…

Human-Computer Interaction · Computer Science 2025-10-22 Yixue Cai , Xiyan Su , Dongpeng Yao , Rongduo Han , Nan Gao , Haining Zhang

Advances in large language models (LLMs) have empowered a variety of applications. However, there is still a significant gap in research when it comes to understanding and enhancing the capabilities of LLMs in the field of mental health. In…

Computation and Language · Computer Science 2024-01-30 Xuhai Xu , Bingsheng Yao , Yuanzhe Dong , Saadia Gabriel , Hong Yu , James Hendler , Marzyeh Ghassemi , Anind K. Dey , Dakuo Wang

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

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