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Age-Related Macular Degeneration (AMD) is an asymptomatic retinal disease which may result in loss of vision. There is limited access to high-quality relevant retinal images and poor understanding of the features defining sub-classes of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Yi-Chieh Liu , Hao-Hsiang Yang , Chao-Han Huck Yang , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , Yi-Chang James Tsai , Jesper Tegner

The emergence of generative AI models has dramatically expanded the availability and use of synthetic data across scientific, industrial, and policy domains. While these developments open new possibilities for data analysis, they also raise…

Machine Learning · Statistics 2026-03-06 Ahmad Abdel-Azim , Ruoyu Wang , Xihong Lin

Synthetic image data generation represents a promising avenue for training deep learning models, particularly in the realm of transfer learning, where obtaining real images within a specific domain can be prohibitively expensive due to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Yuhang Li , Xin Dong , Chen Chen , Jingtao Li , Yuxin Wen , Michael Spranger , Lingjuan Lyu

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…

Generative modeling of anatomical structures plays a crucial role in virtual imaging trials, which allow researchers to perform studies without the costs and constraints inherent to in vivo and phantom studies. For clinical relevance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Bram de Wilde , Max T. Rietberg , Guillaume Lajoinie , Jelmer M. Wolterink

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Benjamin Billot , Colin Magdamo , You Cheng , Steven E. Arnold , Sudeshna Das , Juan. E. Iglesias

Demographic attributes such as age, sex, and race can be predicted from medical images, raising concerns about bias in clinical AI systems. In brain MRI, this signal may arise from anatomical variation, acquisition-dependent contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Mehmet Yigit Avci , Akshit Achara , Andrew King , Jorge Cardoso

Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zirong Li , Siyuan Mei , Weiwen Wu , Andreas Maier , Lina Gölz , Yan Xia

Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Chang Qi , Junyang Chen , Guizhi Xu , Zhenghua Xu , Thomas Lukasiewicz , Yang Liu

Manual brain tumor segmentation from MRI scans is challenging due to tumor heterogeneity, scarcity of annotated data, and class imbalance in medical imaging datasets. Synthetic data generated by generative models has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Aditi Jahagirdar , Sameer Joshi

Generative models such as Large Language Models, Diffusion Models, and generative adversarial networks have recently revolutionized the creation of synthetic data, offering scalable solutions to data scarcity, privacy, and annotation…

Machine Learning · Computer Science 2025-08-28 Dawei Li , Yue Huang , Ming Li , Tianyi Zhou , Xiangliang Zhang , Huan Liu

Training medical AI algorithms requires large volumes of accurately labeled datasets, which are difficult to obtain in the real world. Synthetic images generated from deep generative models can help alleviate the data scarcity problem, but…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Xiaodan Xing , Yang Nan , Federico Felder , Simon Walsh , Guang Yang

Generative models have revolutionized Artificial Intelligence (AI), particularly in multimodal applications. However, adapting these models to the medical domain poses unique challenges due to the complexity of medical data and the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Daniele Molino , Francesco di Feola , Linlin Shen , Paolo Soda , Valerio Guarrasi

Recent generative AI models have achieved remarkable breakthroughs in language and visual understanding. However, although these models can generate realistic visual content, their spatial scale remains confined to bounded environments,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jinqi Cao , Zhiping Yu , Baihong Lin , Chenyang Liu , Zhenwei Shi , Zhengxia Zou

Understanding how human brains interpret and process information is important. Here, we investigated the selectivity and inter-individual differences in human brain responses to images via functional MRI. In our first experiment, we found…

Quantitative Methods · Quantitative Biology 2023-04-20 Zijin Gu , Keith Jamison , Mert R. Sabuncu , Amy Kuceyeski

How will my face look when I get older? Or, for a more challenging question: How will my brain look when I get older? To answer this question one must devise (and learn from data) a multivariate auto-regressive function which given an image…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Tian Xia , Agisilaos Chartsias , Chengjia Wang , Sotirios A. Tsaftaris

In order to achieve good performance and generalisability, medical image segmentation models should be trained on sizeable datasets with sufficient variability. Due to ethics and governance restrictions, and the costs associated with…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Petru-Daniel Tudosiu , Mark S Graham , Tom Vercauteren , M Jorge Cardoso

Magnetic Resonance Imaging (MRI) of the brain has been used to investigate a wide range of neurological disorders, but data acquisition can be expensive, time-consuming, and inconvenient. Multi-site studies present a valuable opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Harrison Nguyen , Richard W. Morris , Anthony W. Harris , Mayuresh S. Korgoankar , Fabio Ramos

Designing generative models for 3D structural brain MRI that synthesize morphologically-plausible and attribute-specific (e.g., age, sex, disease state) samples is an active area of research. Existing approaches based on frameworks like…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Alan Q. Wang , Fangrui Huang , Bailey Trang , Wei Peng , Mohammad Abbasi , Kilian Pohl , Mert Sabuncu , Ehsan Adeli

Multi-contrast MRI acquisitions of an anatomy enrich the magnitude of information available for diagnosis. Yet, excessive scan times associated with additional contrasts may be a limiting factor. Two mainstream approaches for enhanced scan…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Salman Ul Hassan Dar , Mahmut Yurt , Mohammad Shahdloo , Muhammed Emrullah Ildız , Tolga Çukur
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