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The search for pathways that optimize the formation of a particular target molecule in a reaction network is a key problem in many settings, including reactor systems. Chemical reaction networks are mathematically well represented as…

Molecular Networks · Quantitative Biology 2025-06-17 Adittya Pal , Rolf Fagerberg , Jakob Lykke Andersen , Christoph Flamm , Peter Dittrich , Daniel Merkle

Minimum energy path (MEP) search is a vital but often very time-consuming method to predict the transition states of versatile dynamic processes in chemistry, physics, and materials science. In this study, we reveal that the chemical bond…

Materials Science · Physics 2023-07-18 Hongsheng Cai , Guoyuan Liu , Peiqi Qiu , Guangfu Luo

Transition state or minimum energy path finding methods constitute a routine component of the computational chemistry toolkit. Standard analysis involves trajectories conventionally plotted in terms of the relative energy to the initial…

Chemical Physics · Physics 2026-03-09 Rohit Goswami

Accounting for nuclear quantum effects (NQEs) can significantly alter material properties at finite temperatures. Atomic modeling using the path-integral molecular dynamics (PIMD) method can fully account for such effects, but requires…

Materials Science · Physics 2025-05-21 A. A. Solovykh , N. E. Rybin , I. S. Novikov , A. V. Shapeev

In this work, we propose a multi-scale protocol for routine theoretical studies of chemical reaction mechanisms. The initial reaction paths of our investigated systems are sampled using the Nudged-Elastic Band (NEB) method driven by a cheap…

Chemical Physics · Physics 2023-07-26 Tomislav Piskor , Peter Pinski , Thilo Mast , Vladimir V. Rybkin

Autoencoders are important generative models that, among others, have the ability to interpolate image sequences. However, interpolated images are usually not semantically meaningful.In this paper, motivated by dynamic optimal transport, we…

Optimization and Control · Mathematics 2024-04-16 Xue Feng , Thomas Strohmer

We consider an inertial primal-dual fixed point algorithm (IPDFP) to compute the minimizations of the following Problem (1.1). This is a full splitting approach, in the sense that the nonsmooth functions are processed individually via their…

Optimization and Control · Mathematics 2016-04-20 Meng Wen , Yu-Chao Tang , Jigen Peng

We present an efficient algorithm for calculating the minimum energy path (MEP) and energy barriers between local minima on a multidimensional potential energy surface (PES). Such paths play a central role in the understanding of transition…

Computational Physics · Physics 2012-04-19 Amit Samanta , Weinan E

Adaptive Informative Path Planning with Multimodal Sensing (AIPPMS) considers the problem of an agent equipped with multiple sensors, each with different sensing accuracy and energy costs. The agent's goal is to explore the environment and…

Artificial Intelligence · Computer Science 2022-09-19 Joshua Ott , Edward Balaban , Mykel J. Kochenderfer

Due to critical environmental issues, the power systems have to accommodate a significant level of penetration of renewable generation which requires smart approaches to the power grid control. Associated optimal control problems are…

Optimization and Control · Mathematics 2020-01-30 Juraj Kardos , Drosos Kourounis , Olaf Schenk

Mapping reaction pathways and transition states (TS) is fundamental to chemistry but computationally expensive at scale. The minimum energy pathway (MEP) dictates reaction rates and mechanisms, yet recovering it via electronic-structure…

Chemical Physics · Physics 2026-05-25 Rémi Schlama , Philippe Schwaller

Navigating rigid body objects through crowded environments can be challenging, especially when narrow passages are presented. Existing sampling-based planners and optimization-based methods like mixed integer linear programming (MILP)…

Robotics · Computer Science 2024-09-19 Mingxin Yu , Chuchu Fan

We introduce a simple scheme to efficiently compute photon exchange-correlation contributions due to the coupling to transversal photons as formulated in the newly developed quantum-electrodynamical density functional theory (QEDFT). Our…

Quantum Physics · Physics 2018-04-16 Johannes Flick , Christian Schäfer , Michael Ruggenthaler , Heiko Appel , Angel Rubio

The Performance Estimation Problem (PEP) approach consists in computing worst-case performance bounds on optimization algorithms by solving an optimization problem: one maximizes an error criterion over all initial conditions allowed and…

Optimization and Control · Mathematics 2024-02-13 Anne Rubbens , Nizar Bousselmi , Sebastien Colla , Julien M. Hendrickx

Extracting maximum power available from photovoltaic arrays requires the system operating at the maximum power point (MPP). Therefore, finding the MPP is necessary for efficient operation of PV arrays. The MPP changes with multiple…

Systems and Control · Electrical Eng. & Systems 2020-11-17 Eungkyun Kim , Morgan Warner , Indranil Bhattacharya

Finding optimal reaction coordinates and predicting accurate kinetic rates for activated processes are two of the foremost challenges of molecular simulations. We introduce an algorithm that tackles the two problems at once: starting from a…

Statistical Mechanics · Physics 2023-10-30 Line Mouaffac , Karen Palacio-Rodriguez , Fabio Pietrucci

The nudged elastic band (NEB) method is a commonly used approach for the calculation of minimum energy pathways of kinetic processes. However, the final paths obtained rely heavily on the nature of the initially chosen path. This often…

Materials Science · Physics 2019-04-30 Jason M. Munro , Vincent S. Liu , Venkatraman Gopalan , Ismaila Dabo

This paper aims to efficiently compute transport maps between probability distributions arising from particle representation of bio-physical problems. We develop a bidirectional DeepParticle (BDP) method to learn and generate solutions…

Computational Physics · Physics 2025-04-17 Tan Zhang , Zhongjian Wang , Jack Xin , Zhiwen Zhang

We consider a shape optimization based method for finding the best interpolation data in the compression of images with noise. The aim is to reconstruct missing regions by means of minimizing a data fitting term in an $L^p$-norm between…

Analysis of PDEs · Mathematics 2024-10-11 Zakaria Belhachmi , Thomas Jacumin

We consider the geometric optics problem of finding a system of two reflectors that transform a spherical wavefront into a beam of parallel rays with prescribed intensity distribution. Using techniques from optimal transportation theory, it…

Numerical Analysis · Mathematics 2011-11-08 Tilmann Glimm , Nick Henscheid