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Related papers: Observation-Guided Diffusion Probabilistic Models

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Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

High-quality reconstruction of Aerosol Optical Depth (AOD) fields is critical for Atmosphere monitoring, yet current models remain constrained by the scarcity of complete training data and a lack of uncertainty quantification.To address…

Machine Learning · Computer Science 2026-01-01 Linhao Fan , Hongqiang Fang , Jingyang Dai , Yong Jiang , Qixing Zhang

Diffusion models have become fundamental tools for modeling data distributions in machine learning. Despite their success, these models face challenges when generating data with extreme brightness values, as evidenced by limitations…

Machine Learning · Statistics 2026-04-10 Takuro Kutsuna

Diffusion-based generative models have recently emerged as powerful solutions for high-quality synthesis in multiple domains. Leveraging the bidirectional Markov chains, diffusion probabilistic models generate samples by inferring the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Mengyi Zhao , Mengyuan Liu , Bin Ren , Shuling Dai , Nicu Sebe

Diffusion models generate new samples by progressively decreasing the noise from the initially provided random distribution. This inference procedure generally utilizes a trained neural network numerous times to obtain the final output,…

Out-of-distribution (OOD) detection is important for deploying machine learning models in the real world, where test data from shifted distributions can naturally arise. While a plethora of algorithmic approaches have recently emerged for…

Machine Learning · Computer Science 2021-12-03 Peyman Morteza , Yixuan Li

While text-to-video diffusion models have made significant strides, many still face challenges in generating videos with temporal consistency. Within diffusion frameworks, guidance techniques have proven effective in enhancing output…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Hyelin Nam , Jaemin Kim , Dohun Lee , Jong Chul Ye

Diffusion models achieve state-of-the-art image generation but remain computationally costly due to iterative denoising. Latent-space models like Stable Diffusion reduce overhead yet lose fine detail, while retrieval-augmented methods…

Machine Learning · Computer Science 2025-12-23 Bilal Faye , Hanane Azzag , Mustapha Lebbah

Unsupervised out-of-distribution (OOD) detection aims to identify out-of-domain data by learning only from unlabeled In-Distribution (ID) training samples, which is crucial for developing a safe real-world machine learning system. Current…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Ying Yang , De Cheng , Chaowei Fang , Yubiao Wang , Changzhe Jiao , Lechao Cheng , Nannan Wang

Diffusion models are a state-of-the-art generative modeling framework that transform noise to images via Langevin sampling, guided by the score, which is the gradient of the logarithm of the data distribution. Recent works have shown…

Machine Learning · Computer Science 2025-08-01 Aadithya Srikanth , Siddarth Asokan , Nishanth Shetty , Chandra Sekhar Seelamantula

We present a concise, self-contained derivation of diffusion-based generative models. Starting from basic properties of Gaussian distributions (densities, quadratic expectations, re-parameterisation, products, and KL divergences), we…

Machine Learning · Computer Science 2025-11-18 Sepehr Maleki , Negar Pourmoazemi

Image anomaly detection plays a vital role in applications such as industrial quality inspection and medical imaging, where it directly contributes to improving product quality and system reliability. However, existing methods often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Zekang Weng , Jinjin Shi , Jinwei Wang , Zeming Han

Inverse design refers to the problem of optimizing the input of an objective function in order to enact a target outcome. For many real-world engineering problems, the objective function takes the form of a simulator that predicts how the…

Denoising Diffusion Probabilistic Models (DDPMs) have recently achieved remarkable results in conditional and unconditional image generation. The pre-trained models can be adapted without further training to different downstream tasks, by…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Asya Grechka , Guillaume Couairon , Matthieu Cord

Diffusion-based generative models are extremely effective in generating high-quality images, with generated samples often surpassing the quality of those produced by other models under several metrics. One distinguishing feature of these…

Machine Learning · Computer Science 2022-10-25 Ashwini Pokle , Zhengyang Geng , Zico Kolter

Masked Diffusion Models (MDMs) have emerged as one of the most promising paradigms for generative modeling over discrete domains. It is known that MDMs effectively train to decode tokens in a random order, and that this ordering has…

Machine Learning · Computer Science 2025-11-25 Prateek Garg , Bhavya Kohli , Sunita Sarawagi

Out-of-distribution (OOD) detection is a critical task in machine learning that seeks to identify abnormal samples. Traditionally, unsupervised methods utilize a deep generative model for OOD detection. However, such approaches require a…

Machine Learning · Computer Science 2024-10-25 Alvin Heng , Alexandre H. Thiery , Harold Soh

Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

Despite the proliferation of generative models, achieving fast sampling during inference without compromising sample diversity and quality remains challenging. Existing models such as Denoising Diffusion Probabilistic Models (DDPM) deliver…

Machine Learning · Computer Science 2023-10-12 Yanwu Xu , Mingming Gong , Shaoan Xie , Wei Wei , Matthias Grundmann , Kayhan Batmanghelich , Tingbo Hou

Out-of-distribution (OOD) detection is crucial for the safety and reliability of artificial intelligence algorithms, especially in the medical domain. In the context of the Medical OOD (MOOD) detection challenge 2023, we propose a pipeline…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim