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The recent development of artificial intelligence (AI) technology, especially the advance of deep neural network (DNN) technology, has revolutionized many fields. While DNN plays a central role in modern AI technology, it has been rarely…

Machine Learning · Statistics 2023-12-07 Tingting Hou , Chang Jiang , Qing Lu

Generating synthetic data for financial time series poses challenges, especially considering their non-stationary nature. Traditional statistical time series models normally assume weak stationarity. However, this assumption can constrain…

Computational Engineering, Finance, and Science · Computer Science 2026-05-22 Marco Gregnanin , Johannes De Smedt , Giorgio Gnecco , Maurizio Parton

Recent success in deep learning has generated immense interest among practitioners and students, inspiring many to learn about this new technology. While visual and interactive approaches have been successfully developed to help people more…

Human-Computer Interaction · Computer Science 2018-09-06 Minsuk Kahng , Nikhil Thorat , Duen Horng Chau , Fernanda Viégas , Martin Wattenberg

The association of a given human phenotype to a genetic variant remains a critical challenge for biology. We present a novel system called PhenoLinker capable of associating a score to a phenotype-gene relationship by using heterogeneous…

We present an analysis of different techniques for selecting the connection be- tween layers of deep neural networks. Traditional deep neural networks use ran- dom connection tables between layers to keep the number of connections small and…

Computer Vision and Pattern Recognition · Computer Science 2013-06-04 Eugenio Culurciello , Jonghoon Jin , Aysegul Dundar , Jordan Bates

Deep neural networks (DNNs) are vulnerable to adversarial examples, which are crafted by adding imperceptible perturbations to inputs. Recently different attacks and strategies have been proposed, but how to generate adversarial examples…

Machine Learning · Computer Science 2021-01-13 Tao Bai , Jun Zhao , Jinlin Zhu , Shoudong Han , Jiefeng Chen , Bo Li , Alex Kot

Deep Evolutionary Network Structured Representation (DENSER) is a novel approach to automatically design Artificial Neural Networks (ANNs) using Evolutionary Computation. The algorithm not only searches for the best network topology (e.g.,…

Neural and Evolutionary Computing · Computer Science 2018-11-28 Filipe Assunção , Nuno Lourenço , Penousal Machado , Bernardete Ribeiro

Modelling in finance is a challenging task: the data often has complex statistical properties and its inner workings are largely unknown. Deep learning algorithms are making progress in the field of data-driven modelling, but the lack of…

Computational Finance · Quantitative Finance 2021-07-07 Florian Eckerli , Joerg Osterrieder

We propose generative neural network methods to generate DNA sequences and tune them to have desired properties. We present three approaches: creating synthetic DNA sequences using a generative adversarial network; a DNA-based variant of…

Machine Learning · Computer Science 2017-12-19 Nathan Killoran , Leo J. Lee , Andrew Delong , David Duvenaud , Brendan J. Frey

Data-driven methods are widely used to develop physical models, but there still exist limitations that affect their performance, generalizability and robustness. By combining gene expression programming (GEP) with artificial neural network…

Computational Physics · Physics 2023-01-19 Haochen Li , Fabian Waschkowski , Yaomin Zhao , Richard D. Sandberg

Transcriptomic data is a treasure-trove in modern molecular biology, as it offers a comprehensive viewpoint into the intricate nuances of gene expression dynamics underlying biological systems. This genetic information must be utilised to…

Molecular Networks · Quantitative Biology 2023-12-13 Vikram Singh , Vikram Singh

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

Machine Learning · Computer Science 2024-04-24 Rita T. Sousa , Heiko Paulheim

Obtaining models that capture imaging markers relevant for disease progression and treatment monitoring is challenging. Models are typically based on large amounts of data with annotated examples of known markers aiming at automating…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 Thomas Schlegl , Philipp Seeböck , Sebastian M. Waldstein , Ursula Schmidt-Erfurth , Georg Langs

Deep learning based generative adversarial networks (GAN) can effectively perform image reconstruction with under-sampled MR data. In general, a large number of training samples are required to improve the reconstruction performance of a…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 Jun Lv , Guangyuan Li , Xiangrong Tong , Weibo Chen , Jiahao Huang , Chengyan Wang , Guang Yang

Recent technological advances have introduced new high-throughput methods for studying host-virus interactions, but testing synergistic interactions between host gene pairs during infection remains relatively slow and labor intensive.…

Generative adversarial networks (GANs) generate data based on minimizing a divergence between two distributions. The choice of that divergence is therefore critical. We argue that the divergence must take into account the hypothesis set and…

Machine Learning · Computer Science 2019-11-07 Ben Adlam , Corinna Cortes , Mehryar Mohri , Ningshan Zhang

Deep Neural Networks (DNNs) show a significant impact on medical imaging. One significant problem with adopting DNNs for skin cancer classification is that the class frequencies in the existing datasets are imbalanced. This problem hinders…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Ibrahim Saad Ali , Mamdouh Farouk Mohamed , Yousef Bassyouni Mahdy

In agricultural image analysis, optimal model performance is keenly pursued for better fulfilling visual recognition tasks (e.g., image classification, segmentation, object detection and localization), in the presence of challenges with…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Ebenezer Olaniyi , Dong Chen , Yuzhen Lu , Yanbo Huang

Genomic data I used in many fields but, it has become known that most of the platforms used in the sequencing process produce significant errors. This means that the analysis and inferences generated from these data may have some errors…

Genomics · Quantitative Biology 2024-09-05 Ferdinand Kartriku , Robert Sowah , Charles Saah