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Motivation: The consistent amount of different types of omics data requires novel methods of analysis and data integration. In this work we describe Regression2Net, a computational approach to analyse gene expression and methylation…

Computational Engineering, Finance, and Science · Computer Science 2015-07-06 Francesco Gadaleta , Kyrylo Bessonov

Brain tumors represent one of the most critical neurological conditions, where early and accurate diagnosis is directly correlated with patient survival rates. Manual interpretation of Magnetic Resonance Imaging (MRI) scans is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Chinedu Emmanuel Mbonu , Tochukwu Sunday Belonwu , Okwuchukwu Ejike Chukwuogo , Kenechukwu Sylvanus Anigbogu

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Binghua Li , Jie Mao , Zhe Sun , Chao Li , Qibin Zhao , Toshihisa Tanaka

Structural magnetic resonance imaging (MRI) has been widely utilized for analysis and diagnosis of brain diseases. Automatic segmentation of brain tumors is a challenging task for computer-aided diagnosis due to low-tissue contrast in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Multimodal magnetic resonance imaging (MRI) is crucial for brain tumor segmentation, with many methods leveraging its four key modalities to capture complementary information for effective sub-region analysis. However, the absence of…

Artificial Intelligence · Computer Science 2026-05-19 Sha Tao , Jiao Pan , Yu Guo , Chao Yao

A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Yiming Yao , Peisheng Qian , Ziyuan Zhao , Zeng Zeng

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Finding, identifying and segmenting suspicious cancer metastasized lymph nodes from 3D multi-modality imaging is a clinical task of paramount importance. In radiotherapy, they are referred to as Lymph Node Gross Tumor Volume (GTVLN).…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Zhuotun Zhu , Dakai Jin , Ke Yan , Tsung-Ying Ho , Xianghua Ye , Dazhou Guo , Chun-Hung Chao , Jing Xiao , Alan Yuille , Le Lu

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

Image and Video Processing · Electrical Eng. & Systems 2026-05-14 Md Fahimul Kabir Chowdhury , Jannatul Ferdous

Brain Metastases (BM) complicate 20-40% of cancer cases. BM lesions can present as punctate (1 mm) foci, requiring high-precision Magnetic Resonance Imaging (MRI) in order to prevent inadequate or delayed BM treatment. However, BM lesion…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Engin Dikici , John L. Ryu , Mutlu Demirer , Matthew Bigelow , Richard D. White , Wayne Slone , Barbaros Selnur Erdal , Luciano M. Prevedello

Background: State-of-the art selection methods fail to identify weak but cumulative effects of features found in many high-dimensional omics datasets. Nevertheless, these features play an important role in certain diseases. Results: We…

Gliomas, among the most common primary brain tumors, vary widely in aggressiveness, prognosis, and histology, making treatment challenging due to complex and time-intensive surgical interventions. This study presents an Attention-Gated…

Artificial Intelligence · Computer Science 2026-02-18 Rut Pate , Snehal Rajput , Mehul S. Raval , Rupal A. Kapdi , Mohendra Roy

This research presents an enhanced approach for precise segmentation of brain tumor masses in magnetic resonance imaging (MRI) using an advanced 3D-UNet model combined with a Context Transformer (CoT). By architectural expansion CoT, the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Thien-Qua T. Nguyen , Hieu-Nghia Nguyen , Thanh-Hieu Bui , Thien B. Nguyen-Tat , Vuong M. Ngo

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

Segmenting brain tumors in multi-parametric magnetic resonance imaging enables performing quantitative analysis in support of clinical trials and personalized patient care. This analysis provides the potential to impact clinical…

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Brain tumors are among the deadliest diseases in the world. Magnetic Resonance Imaging (MRI) is one of the most effective ways to detect brain tumors. Accurate detection of brain tumors based on MRI scans is critical, as it can potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Xiaoyi Liu , Zhuoyue Wang

Timely brain tumor diagnosis remains challenging in low-resource clinical environments where expert neuroradiology interpretation, high-end MRI hardware, and invasive biopsy procedures may be limited. Although deep learning has achieved…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Areeb Ehsan