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The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

We explore semantic segmentation beyond the conventional, single-dataset homogeneous training and bring forward the problem of Heterogeneous Training of Semantic Segmentation (HTSS). HTSS involves simultaneous training on multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Panagiotis Meletis , Gijs Dubbelman

Mixup~\cite{zhang2017mixup} is a recently proposed method for training deep neural networks where additional samples are generated during training by convexly combining random pairs of images and their associated labels. While simple to…

Machine Learning · Statistics 2020-01-08 Sunil Thulasidasan , Gopinath Chennupati , Jeff Bilmes , Tanmoy Bhattacharya , Sarah Michalak

Deep Neural Networks (DNN) have shown great promise in many classification applications, yet are widely known to have poorly calibrated predictions when they are over-parametrized. Improving DNN calibration without comprising on model…

Machine Learning · Computer Science 2024-05-07 Mikkel Jordahn , Pablo M. Olmos

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Skin cancer is the most common malignancy in the world. Automated skin cancer detection would significantly improve early detection rates and prevent deaths. To help with this aim, a number of datasets have been released which can be used…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Michael Luke Battle , Amir Atapour-Abarghouei , Andrew Stephen McGough

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

How deep neural networks (DNNs) learn from noisy labels has been studied extensively in image classification but much less in image segmentation. So far, our understanding of the learning behavior of DNNs trained by noisy segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-08 Yaoru Luo , Guole Liu , Yuanhao Guo , Ge Yang

Objective: Medical image datasets with pixel-level labels tend to have a limited number of organ or tissue label classes annotated, even when the images have wide anatomical coverage. With supervised learning, multiple classifiers are…

In the context of classification problems, Deep Learning (DL) approaches represent state of art. Many DL approaches are based on variations of standard multi-layer feed-forward neural networks. These are also referred to as deep networks.…

Machine Learning · Computer Science 2023-11-21 Andrea Apicella , Francesco Isgrò , Roberto Prevete

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Navid Alemi Koohababni , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each…

Quantitative Methods · Quantitative Biology 2016-12-05 Stefan Bauer , Nicolas Carion , Peter Schüffler , Thomas Fuchs , Peter Wild , Joachim M. Buhmann

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Deep neural networks (DNNs) offer a means of addressing the challenging task of clustering high-dimensional data. DNNs can extract useful features, and so produce a lower dimensional representation, which is more amenable to clustering…

Machine Learning · Computer Science 2021-07-23 Louis Mahon , Thomas Lukasiewicz

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

Deep Neural Networks (DNNs), with its promising performance, are being increasingly used in safety critical applications such as autonomous driving, cancer detection, and secure authentication. With growing importance in deep learning,…

Machine Learning · Computer Science 2019-11-19 Senthil Mani , Anush Sankaran , Srikanth Tamilselvam , Akshay Sethi

Due to the intensive cost of labor and expertise in annotating 3D medical images at a voxel level, most benchmark datasets are equipped with the annotations of only one type of organs and/or tumors, resulting in the so-called partially…

Computer Vision and Pattern Recognition · Computer Science 2020-11-23 Jianpeng Zhang , Yutong Xie , Yong Xia , Chunhua Shen
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