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Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

Image dehazing is quite challenging in dense-haze scenarios, where quite less original information remains in the hazy image. Though previous methods have made marvelous progress, they still suffer from information loss in content and color…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Hu Yu , Jie Huang , Kaiwen Zheng , Feng Zhao

This article provides a mathematically rigorous introduction to denoising diffusion probabilistic models (DDPMs), sometimes also referred to as diffusion probabilistic models or diffusion models, for generative artificial intelligence. We…

Machine Learning · Computer Science 2024-12-03 Davide Gallon , Arnulf Jentzen , Philippe von Wurstemberger

Despite the recent visually-pleasing results achieved, the massive computational cost has been a long-standing flaw for diffusion probabilistic models (DPMs), which, in turn, greatly limits their applications on resource-limited platforms.…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Xingyi Yang , Daquan Zhou , Jiashi Feng , Xinchao Wang

Recent advancements in diffusion models have demonstrated significant success in unsupervised anomaly segmentation. For anomaly segmentation, these models are first trained on normal data; then, an anomalous image is noised to an…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Mehrdad Moradi , Kamran Paynabar

Diffusion models are distinguished by their exceptional generative performance, particularly in producing high-quality samples through iterative denoising. While current theory suggests that the number of denoising steps required for…

Machine Learning · Computer Science 2025-04-08 Gen Li , Changxiao Cai , Yuting Wei

Recently, diffusion models (DMs) have made significant strides in high-quality image generation. However, the multi-step denoising process often results in considerable computational overhead, impeding deployment on resource-constrained…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yu-Shan Tai , An-Yeu , Wu

Diffusion models have garnered significant attention since they can effectively learn complex multivariate Gaussian distributions, resulting in diverse, high-quality outcomes. They introduce Gaussian noise into training data and reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Vidya Prasad , Chen Zhu-Tian , Anna Vilanova , Hanspeter Pfister , Nicola Pezzotti , Hendrik Strobelt

Recent advances in masked diffusion language models (MDLMs) narrow the quality gap to autoregressive LMs, but their sampling remains expensive because generation requires many full-sequence denoising passes with a large Transformer and,…

Machine Learning · Computer Science 2026-04-14 Ivan Sedykh , Nikita Sorokin , Valentin Malykh

Stepwise signals are ubiquitous in single-molecule detections, where abrupt changes in signal levels typically correspond to molecular conformational changes or state transitions. However, these features are inevitably obscured by noise,…

Signal Processing · Electrical Eng. & Systems 2026-02-10 Xingdi Tong , Chenyu Wen

We present a comprehensive comparative study of three generative modeling paradigms: Denoising Diffusion Probabilistic Models (DDPM), Conditional Flow Matching (CFM), and MeanFlow. While DDPM and CFM require iterative sampling, MeanFlow…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Umang Agarwal , Rudraksh Sangore , Sumit Laddha

We introduce the Fixed Point Diffusion Model (FPDM), a novel approach to image generation that integrates the concept of fixed point solving into the framework of diffusion-based generative modeling. Our approach embeds an implicit fixed…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xingjian Bai , Luke Melas-Kyriazi

Diffusion models have emerged as powerful generative tools, rivaling GANs in sample quality and mirroring the likelihood scores of autoregressive models. A subset of these models, exemplified by DDIMs, exhibit an inherent asymmetry: they…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Yixuan Wang , Shuangyin Li

Diffusion models (DMs) have shown promising results on single-image super-resolution and other image-to-image translation tasks. Benefiting from more computational resources and longer inference times, they are able to yield more realistic…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yuanting Fan , Chengxu Liu , Nengzhong Yin , Changlong Gao , Xueming Qian

Diffusion models have shown remarkable performance on many generative tasks. Despite recent success, most diffusion models are restricted in that they only allow linear transformation of the data distribution. In contrast, broader family of…

Machine Learning · Computer Science 2024-06-04 Grigory Bartosh , Dmitry Vetrov , Christian A. Naesseth

Denoising diffusion probabilistic models (DDPMs) are a recent family of generative models that achieve state-of-the-art results. In order to obtain class-conditional generation, it was suggested to guide the diffusion process by gradients…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Bahjat Kawar , Roy Ganz , Michael Elad

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Diffusion models (DMs) represent state-of-the-art generative models for continuous inputs. DMs work by constructing a Stochastic Differential Equation (SDE) in the input space (ie, position space), and using a neural network to reverse it.…

Machine Learning · Computer Science 2024-05-14 Tianrong Chen , Jiatao Gu , Laurent Dinh , Evangelos A. Theodorou , Joshua Susskind , Shuangfei Zhai

Diffusion models (DMs) have become the dominant paradigm of generative modeling in a variety of domains by learning stochastic processes from noise to data. Recently, diffusion denoising bridge models (DDBMs), a new formulation of…

Machine Learning · Computer Science 2024-11-01 Guande He , Kaiwen Zheng , Jianfei Chen , Fan Bao , Jun Zhu