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Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

Protein language models (pLMs) produce per-residue representations that capture evolutionary and structural information, yet their mean-pooled sequence embeddings are not explicitly trained to reflect functional, evolutionary or structural…

Machine Learning · Computer Science 2026-05-11 Dan Ofer , Oriel Perets , Michal Linial , Nadav Rappoport

Current protein language models (PLMs) learn protein representations mainly based on their sequences, thereby well capturing co-evolutionary information, but they are unable to explicitly acquire protein functions, which is the end goal of…

Biomolecules · Quantitative Biology 2023-07-06 Minghao Xu , Xinyu Yuan , Santiago Miret , Jian Tang

Large pre-trained multilingual models like mBERT, XLM-R achieve state of the art results on language understanding tasks. However, they are not well suited for latency critical applications on both servers and edge devices. It's important…

Computation and Language · Computer Science 2021-01-25 Prabhu Kaliamoorthi , Aditya Siddhant , Edward Li , Melvin Johnson

Retrieval-augmented language models (LMs) have received much attention recently. However, typically the retriever is not trained jointly as a native component of the LM, but added post-hoc to an already-pretrained LM, which limits the…

Computation and Language · Computer Science 2024-07-23 Ohad Rubin , Jonathan Berant

Masked diffusion language models (MDLMs) offer the potential for parallel token generation, but most open-source MDLMs decode fewer than 5 tokens per model forward pass even with sophisticated sampling strategies, limiting their parallel…

Machine Learning · Computer Science 2026-02-09 Shirui Chen , Jiantao Jiao , Lillian J. Ratliff , Banghua Zhu

Encoder-decoder models have achieved remarkable success in speech and text tasks, yet efficiently adapting these models to diverse uni/multi-modal scenarios remains an open challenge. In this paper, we propose Whisper-UT, a unified and…

We present Pre-trained Machine Reader (PMR), a novel method for retrofitting pre-trained masked language models (MLMs) to pre-trained machine reading comprehension (MRC) models without acquiring labeled data. PMR can resolve the discrepancy…

Computation and Language · Computer Science 2023-10-17 Weiwen Xu , Xin Li , Wenxuan Zhang , Meng Zhou , Wai Lam , Luo Si , Lidong Bing

The ribosomal density along the coding region of the mRNA molecule affect various fundamental intracellular phenomena including: protein production rates, organismal fitness, ribosomal drop off, and co-translational protein folding. Thus,…

Genomics · Quantitative Biology 2017-05-19 Yoram Zarai , Michael Margaliot , Eduardo D. Sontag , Tamir Tuller

Recent advances in large language models (LLMs) provide robots with contextual reasoning abilities to comprehend human instructions. Yet, current LLM-enabled robots typically depend on cloud-based models or high-performance computing…

Robotics · Computer Science 2026-04-15 Wenhao Wang , Yanyan Li , Long Jiao , Jiawei Yuan

In this paper, we evaluate the capability of transformer-based language models in making inferences over uncertain text that includes uncertain rules of reasoning. We cover both Pre-trained Language Models (PLMs) and generative Large…

Computation and Language · Computer Science 2024-02-12 Aliakbar Nafar , Kristen Brent Venable , Parisa Kordjamshidi

This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

Machine Learning · Computer Science 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

Recent advancements in language models (LMs) have gained substantial attentions on their capability to generate human-like responses. Though exhibiting a promising future for various applications such as conversation AI, these LMs face…

Machine Learning · Computer Science 2023-09-14 Yufei Li , Zexin Li , Wei Yang , Cong Liu

This study investigates the in-context learning capabilities of various decoder-only transformer-based language models with different model sizes and training data, including GPT2, SmolLM2, OpenELM, TinyLlama, Stable LM, and Gemma 2. We…

Computation and Language · Computer Science 2025-02-24 Yen-Che Hsiao , Abhishek Dutta

While speech foundation models (SFMs) have demonstrated remarkable performance in audio-only tasks, their adaptation to multimodal scenarios remains underexplored. This work presents UASR-LLM, a novel framework that adapts frozen SFMs to…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-03 Jing-Xuan Zhang , Genshun Wan , Jin Li , Jianqing Gao , Duo Zhao , Zhen-Hua Ling

Recent advances in large language models (LLMs) have highlighted the potential of reinforcement learning with verifiable rewards (RLVR) to enhance reasoning capabilities through extended output sequences. However, traditional RL frameworks…

Computation and Language · Computer Science 2025-07-29 Dong Du , Shulin Liu , Tao Yang , Shaohua Chen , Yang Li

General-purpose Large Language Models (LLMs) like GPT-4 have achieved remarkable advancements in machine translation (MT) by leveraging extensive web content. On the other hand, translation-specific LLMs are built by pre-training on…

Computation and Language · Computer Science 2024-10-30 Zhaopeng Feng , Ruizhe Chen , Yan Zhang , Zijie Meng , Zuozhu Liu

Assessing response quality to instructions in language models is vital but challenging due to the complexity of human language across different contexts. This complexity often results in ambiguous or inconsistent interpretations, making…

Multimodal Machine Translation (MMT) aims to improve translation quality by leveraging auxiliary modalities such as images alongside textual input. While recent advances in large-scale pre-trained language and vision models have…

Computation and Language · Computer Science 2025-04-28 Zhuang Yu , Shiliang Sun , Jing Zhao , Tengfei Song , Hao Yang

Adapting pre-trained text Large Language Models (LLMs) into Speech Language Models (Speech LMs) via continual pretraining on speech data is promising, but often degrades the original text capabilities. We propose Multimodal Depth Upscaling,…

Computation and Language · Computer Science 2026-04-02 Kazuki Yano , Jun Suzuki , Shinji Watanabe
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