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Related papers: Classifying Whole Slide Images: What Matters?

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Encoding whole slide images (WSI) as graphs is well motivated since it makes it possible for the gigapixel resolution WSI to be represented in its entirety for the purpose of graph learning. To this end, WSIs can be broken into smaller…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Milan Aryal , Nasim Yahyasoltani

Whole-slide image (WSI) analysis remains challenging due to the gigapixel scale and sparsely distributed diagnostic regions. Multiple Instance Learning (MIL) mitigates this by modeling the WSI as bags of patches for slide-level prediction.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yujian Liu , Yuechuan Lin , Dongxu Shen , Haoran Li , Yutong Wang , Xiaoli Liu , Shidang Xu

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Sobhan Hemati , Ghazal Alabtah , Saghir Alfasly , H. R. Tizhoosh

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations, emphasizing significant…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Jiawen Li , Yuxuan Chen , Hongbo Chu , Qiehe Sun , Tian Guan , Anjia Han , Yonghong He

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Whole slide image (WSI) classification often relies on deep weakly supervised multiple instance learning (MIL) methods to handle gigapixel resolution images and slide-level labels. Yet the decent performance of deep learning comes from…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Jiawei Yang , Hanbo Chen , Yu Zhao , Fan Yang , Yao Zhang , Lei He , Jianhua Yao

The histopathological images contain a huge amount of information, which can make diagnosis an extremely timeconsuming and tedious task. In this study, we developed a completely automated system to detect regions of interest (ROIs) in whole…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Mohammed Lamine Benomar , Nesma Settouti , Eric Debreuve , Xavier Descombes , Damien Ambrosetti

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

The automatic registration of differently stained whole slide images (WSIs) is crucial for improving diagnosis and prognosis by fusing complementary information emerging from different visible structures. It is also useful to quickly…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Marek Wodzinski , Niccolò Marini , Manfredo Atzori , Henning Müller

Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient's paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Hong Liu , Wen-Dong Xu , Zi-Hao Shang , Xiang-Dong Wang , Hai-Yan Zhou , Ke-Wen Ma , Huan Zhou , Jia-Lin Qi , Jia-Rui Jiang , Li-Lan Tan , Hui-Min Zeng , Hui-Juan Cai , Kuan-Song Wang , Yue-Liang Qian

The whole slide image (WSI) classification is often formulated as a multiple instance learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI, existing MIL methods intuitively focus on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenhao Tang , Sheng Huang , Xiaoxian Zhang , Fengtao Zhou , Yi Zhang , Bo Liu

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu
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