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Current approaches to explaining the decisions of deep learning systems for medical tasks have focused on visualising the elements that have contributed to each decision. We argue that such approaches are not enough to "open the black box"…

Artificial Intelligence · Computer Science 2018-06-04 William Gale , Luke Oakden-Rayner , Gustavo Carneiro , Andrew P Bradley , Lyle J Palmer

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Despite their success, Large-Language Models (LLMs) still face criticism due to their lack of interpretability. Traditional post-hoc interpretation methods, based on attention and gradient-based analysis, offer limited insights as they only…

Computation and Language · Computer Science 2025-07-17 Francesco De Santis , Philippe Bich , Gabriele Ciravegna , Pietro Barbiero , Danilo Giordano , Tania Cerquitelli

Concept Bottleneck Models (CBMs) decompose image classification into a process governed by interpretable, human-readable concepts. Recent advances in CBMs have used Large Language Models (LLMs) to generate candidate concepts. However, a…

Computation and Language · Computer Science 2025-06-03 Yiwen Jiang , Deval Mehta , Wei Feng , Zongyuan Ge

Concept-based models aim to explain model decisions with human-understandable concepts. However, most existing approaches treat concepts as numerical attributes, without providing complementary visual explanations that could localize the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Cristiano Patrício , Luís F. Teixeira , João C. Neves

Multimodal pre-trained models, such as CLIP, are popular for zero-shot classification due to their open-vocabulary flexibility and high performance. However, vision-language models, which compute similarity scores between images and class…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Mia Chiquier , Utkarsh Mall , Carl Vondrick

Despite tremendous progress in computer vision, there has not been an attempt for machine learning on very large-scale medical image databases. We present an interleaved text/image deep learning system to extract and mine the semantic…

Computer Vision and Pattern Recognition · Computer Science 2015-05-05 Hoo-Chang Shin , Le Lu , Lauren Kim , Ari Seff , Jianhua Yao , Ronald M. Summers

Interpretability is a critical factor in applying complex deep learning models to advance the understanding of brain disorders in neuroimaging studies. To interpret the decision process of a trained classifier, existing techniques typically…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Zixuan Liu , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

To interpret deep models' predictions, attention-based visual cues are widely used in addressing \textit{why} deep models make such predictions. Beyond that, the current research community becomes more interested in reasoning \textit{how}…

Computer Vision and Pattern Recognition · Computer Science 2022-05-27 Wenxiao Xiao , Zhengming Ding , Hongfu Liu

Interpretable deep learning aims at developing neural architectures whose decision-making processes could be understood by their users. Among these techniqes, Concept Bottleneck Models enhance the interpretability of neural networks by…

Machine Learning · Computer Science 2024-05-28 Gabriele Dominici , Pietro Barbiero , Francesco Giannini , Martin Gjoreski , Marc Langhenirich

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Deep learning methods have become very popular for the processing of natural images, and were then successfully adapted to the neuroimaging field. As these methods are non-transparent, interpretability methods are needed to validate them…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Elina Thibeau-Sutre , Sasha Collin , Ninon Burgos , Olivier Colliot

In this paper, we introduce an explainable algorithm designed from a multi-modal foundation model, that performs fast and explainable image classification. Drawing inspiration from CLIP-based Concept Bottleneck Models (CBMs), our method…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Rémi Kazmierczak , Eloïse Berthier , Goran Frehse , Gianni Franchi

To increase the transparency of modern computer-aided diagnosis (CAD) systems for assessing the malignancy of lung nodules, an interpretable model based on applying the generalized additive models and the concept-based learning is proposed.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Rinat I. Dumaev , Sergei A. Molodyakov , Lev V. Utkin

Unlike nature image classification where groundtruth label is explicit and of no doubt, physicians commonly interpret medical image conditioned on certainty like using phrase "probable" or "likely". Existing medical image datasets either…

Machine Learning · Computer Science 2025-11-21 Kunyu Zhang , Fukang Ge , Binyang Wang , Yingke Chen , Kazuma Kobayashi , Lin Gu , Jinhao Bi , Yingying Zhu

Deep learning architectures based on convolutional neural networks tend to rely on continuous, smooth features. While this characteristics provides significant robustness and proves useful in many real-world tasks, it is strikingly…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Zuzanna Buchnajzer , Kacper Dobek , Stanisław Hapke , Daniel Jankowski , Krzysztof Krawiec

Interpretability is essential for machine learning algorithms in high-stakes application fields such as medical image analysis. However, high-performing black-box neural networks do not provide explanations for their predictions, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner
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