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Variational Autoencoders (VAE) are widely used for dimensionality reduction of large-scale tabular and image datasets, under the assumption of independence between data observations. In practice, however, datasets are often correlated, with…

Machine Learning · Statistics 2024-12-25 Giora Simchoni , Saharon Rosset

Variational autoencoders (VAEs) are widely used deep generative models capable of learning unsupervised latent representations of data. Such representations are often difficult to interpret or control. We consider the problem of…

Machine Learning · Computer Science 2018-12-18 Jack Klys , Jake Snell , Richard Zemel

Density modeling is notoriously difficult for high dimensional data. One approach to the problem is to search for a lower dimensional manifold which captures the main characteristics of the data. Recently, the Gaussian Process Latent…

Machine Learning · Statistics 2010-07-14 Hannes Nickisch , Carl Edward Rasmussen

Estimating causal effects from observational data is challenging, especially in the presence of latent confounders. Much work has been done on addressing this challenge, but most of the existing research ignores the bias introduced by the…

Machine Learning · Computer Science 2024-08-15 Yang Xie , Ziqi Xu , Debo Cheng , Jiuyong Li , Lin Liu , Yinghao Zhang , Zaiwen Feng

We develop data-driven methods incorporating geometric and topological information to learn parsimonious representations of nonlinear dynamics from observations. The approaches learn nonlinear state-space models of the dynamics for general…

Machine Learning · Computer Science 2025-03-28 Ryan Lopez , Paul J. Atzberger

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Understanding the structure of complex, nonstationary, high-dimensional time-evolving signals is a central challenge in scientific data analysis. In many domains, such as speech and biomedical signal processing, the ability to learn…

Machine Learning · Computer Science 2026-01-13 Ioannis Ziogas , Aamna Al Shehhi , Ahsan H. Khandoker , Leontios J. Hadjileontiadis

Multi-component datasets with intricate dependencies, like industrial assemblies or multi-modal imaging, challenge current generative modeling techniques. Existing Multi-component Variational AutoEncoders typically rely on simplified…

Machine Learning · Computer Science 2026-04-07 Fouad Oubari , Mohamed El-Baha , Raphael Meunier , Rodrigue Décatoire , Mathilde Mougeot

State-of-the-art systems neuroscience experiments yield large-scale multimodal data, and these data sets require new tools for analysis. Inspired by the success of large pretrained models in vision and language domains, we reframe the…

Neurons and Cognition · Quantitative Biology 2024-03-19 Antonis Antoniades , Yiyi Yu , Joseph Canzano , William Wang , Spencer LaVere Smith

Studying the complex interactions between different brain regions is crucial in neuroscience. Various statistical methods have explored the latent communication across multiple brain regions. Two main categories are the Gaussian Process…

Neurons and Cognition · Quantitative Biology 2024-05-31 Weihan Li , Chengrui Li , Yule Wang , Anqi Wu

Alzheimer's disease (AD) is characterized by a sequence of pathological changes, which are commonly assessed in vivo using MRI and PET. Currently, the most approaches to analyze statistical associations between brain regions rely on Pearson…

Neurons and Cognition · Quantitative Biology 2020-03-30 Martin Dyrba , Reza Mohammadi , Michel J. Grothe , Thomas Kirste , Stefan J. Teipel

Poisson-distributed latent variable models are widely used in computational neuroscience, but differentiating through discrete stochastic samples remains challenging. Two approaches address this: Exponential Arrival Time (EAT) simulation…

Machine Learning · Statistics 2026-02-05 Michael Ibrahim , Hanqi Zhao , Eli Sennesh , Zhi Li , Anqi Wu , Jacob L. Yates , Chengrui Li , Hadi Vafaii

With the ever-increasing amount of data, the central challenge in multimodal learning involves limitations of labelled samples. For the task of classification, techniques such as meta-learning, zero-shot learning, and few-shot learning…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Nihar Bendre , Kevin Desai , Peyman Najafirad

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Autoencoders and their variants are among the most widely used models in representation learning and generative modeling. However, autoencoder-based models usually assume that the learned representations are i.i.d. and fail to capture the…

Machine Learning · Computer Science 2023-02-10 Ba-Hien Tran , Babak Shahbaba , Stephan Mandt , Maurizio Filippone

Gaussian process state-space models (GPSSMs) provide a principled and flexible approach to modeling the dynamics of a latent state, which is observed at discrete-time points via a likelihood model. However, inference in GPSSMs is…

Machine Learning · Computer Science 2023-07-18 Xuhui Fan , Edwin V. Bonilla , Terence J. O'Kane , Scott A. Sisson

In this work, we explore the latent space of a denoising variational autoencoder with a mixture-of-Gaussians prior (VAE-MoG), trained on gravitational wave data from event GW150914. To evaluate how well the model captures the underlying…

Machine Learning · Computer Science 2025-10-01 Fernanda Zapata Bascuñán

We present a new method to visualize data ensembles by constructing structured probabilistic representations in latent spaces, i.e., lower-dimensional representations of spatial data features. Our approach transforms the spatial features of…

Machine Learning · Computer Science 2025-09-17 Cenyang Wu , Qinhan Yu , Liang Zhou

The variational autoencoder (VAE) is a generative model with continuous latent variables where a pair of probabilistic encoder (bottom-up) and decoder (top-down) is jointly learned by stochastic gradient variational Bayes. We first…

Machine Learning · Statistics 2016-04-19 Suwon Suh , Seungjin Choi

Generative models of observations under interventions have been a vibrant topic of interest across machine learning and the sciences in recent years. For example, in drug discovery, there is a need to model the effects of diverse…

Machine Learning · Statistics 2024-01-17 Michael Bereket , Theofanis Karaletsos
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