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Large Language Models (LLM) have recently been shown to perform well at various tasks from language understanding, reasoning, storytelling, and information search to theory of mind. In an extension of this work, we explore the ability of…

Computation and Language · Computer Science 2023-10-31 Nutchanon Yongsatianchot , Tobias Thejll-Madsen , Stacy Marsella

Artificial intelligence is making spectacular progress, and one of the best examples is the development of large language models (LLMs) such as OpenAI's GPT series. In these lectures, written for readers with a background in mathematics or…

Computation and Language · Computer Science 2023-10-09 Michael R. Douglas

The application of machine learning (ML) in a range of geospatial tasks is increasingly common but often relies on globally available covariates such as satellite imagery that can either be expensive or lack predictive power. Here we…

Computation and Language · Computer Science 2024-02-27 Rohin Manvi , Samar Khanna , Gengchen Mai , Marshall Burke , David Lobell , Stefano Ermon

This work investigates the capabilities of large language models (LLMs) in detecting and understanding human emotions through text. Drawing upon emotion models from psychology, we adopt an interdisciplinary perspective that integrates…

Computation and Language · Computer Science 2025-03-10 Florian Lecourt , Madalina Croitoru , Konstantin Todorov

We show that large language model (LLMs) can be transformed via supervised fine-tuning (SFT) of engineered prompts into SmileyLlama for exploring the chemical space of drug molecules. We benchmark SmileyLlama against pre-trained LLMs and…

Multimodal large language models (MLLMs) have shown remarkable performance in vision-language tasks. However, existing MLLMs are primarily trained on generic datasets, limiting their ability to reason on domain-specific visual cues such as…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Hatef Otroshi Shahreza , Sébastien Marcel

Generative Large Language Models (gLLMs), such as ChatGPT, are increasingly being used in communication research for content analysis. Studies show that gLLMs can outperform both crowd workers and trained coders, such as research…

Artificial Intelligence · Computer Science 2025-10-29 Daria Kravets-Meinke , Hannah Schmid-Petri , Sonja Niemann , Ute Schmid

In drug-discovery-related tasks such as virtual screening, machine learning is emerging as a promising way to predict molecular properties. Conventionally, molecular fingerprints (numerical representations of molecules) are calculated…

Machine Learning · Computer Science 2019-11-13 Shion Honda , Shoi Shi , Hiroki R. Ueda

Molecule discovery plays a crucial role in various scientific fields, advancing the design of tailored materials and drugs. However, most of the existing methods heavily rely on domain experts, require excessive computational cost, or…

Computation and Language · Computer Science 2024-05-10 Jiatong Li , Yunqing Liu , Wenqi Fan , Xiao-Yong Wei , Hui Liu , Jiliang Tang , Qing Li

Molecular generative models, often employing GPT-style language modeling on molecular string representations, have shown promising capabilities when scaled to large datasets and model sizes. However, it remains unclear and subject to debate…

Machine Learning · Computer Science 2026-02-02 Dong Xu , Qihua Pan , Sisi Yuan , Jianqiang Li , Zexuan Zhu , Junkai Ji

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs…

Accurate molecular property prediction requires integrating complementary information from molecular structure and chemical semantics. In this work, we propose LGM-CL, a local-global multimodal contrastive learning framework that jointly…

Machine Learning · Computer Science 2026-02-02 Xiayu Liu , Zhengyi Lu , Yunhong Liao , Chan Fan , Hou-biao Li

This paper presents a novel approach for predicting molecular properties with high accuracy without the need for extensive pre-training. Employing ensemble learning and supervised fine-tuning of BERT, RoBERTa, and XLNet, our method…

Machine Learning · Computer Science 2024-06-12 Junling Hu

This research focuses on assessing the ability of large language models (LLMs) in representing geometries and their spatial relations. We utilize LLMs including GPT-2 and BERT to encode the well-known text (WKT) format of geometries and…

Computation and Language · Computer Science 2023-07-10 Yuhan Ji , Song Gao

Large language models (LLMs) such as ChatGPT can produce coherent, cohesive, relevant, and fluent answers for various natural language processing (NLP) tasks. Taking document-level machine translation (MT) as a testbed, this paper provides…

Computation and Language · Computer Science 2023-10-25 Longyue Wang , Chenyang Lyu , Tianbo Ji , Zhirui Zhang , Dian Yu , Shuming Shi , Zhaopeng Tu

Generative Pretrained Transformers (GPTs) are foundational Large Language Models (LLMs) for text generation. However, individual LLMs often produce inconsistent outputs and exhibit biases, limiting their representation of diverse language…

Computation and Language · Computer Science 2025-08-06 Mari Ashiga , Wei Jie , Fan Wu , Vardan Voskanyan , Fateme Dinmohammadi , Paul Brookes , Jingzhi Gong , Zheng Wang

Social telehealth has revolutionized healthcare by enabling patients to share symptoms and receive medical consultations remotely. Users frequently post symptoms on social media and online health platforms, generating a vast repository of…

Computation and Language · Computer Science 2025-02-04 Malak Mohamed , Rokaia Emad , Ali Hamdi

One reason pretraining on self-supervised linguistic tasks is effective is that it teaches models features that are helpful for language understanding. However, we want pretrained models to learn not only to represent linguistic features,…

Computation and Language · Computer Science 2020-10-13 Alex Warstadt , Yian Zhang , Haau-Sing Li , Haokun Liu , Samuel R. Bowman

Existing text representations such as embeddings and bag-of-words are not suitable for rule learning due to their high dimensionality and absent or questionable feature-level interpretability. This article explores whether large language…

Machine Learning · Computer Science 2025-10-02 Vojtěch Balek , Lukáš Sýkora , Vilém Sklenák , Tomáš Kliegr

Most pre-trained language models (PLMs) construct word representations at subword level with Byte-Pair Encoding (BPE) or its variations, by which OOV (out-of-vocab) words are almost avoidable. However, those methods split a word into…

Computation and Language · Computer Science 2021-05-17 Wentao Ma , Yiming Cui , Chenglei Si , Ting Liu , Shijin Wang , Guoping Hu