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Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targeted alterations at the single nucleotide level. However,…

Genomics · Quantitative Biology 2023-11-16 Amina Mollaysa , Ahmed Allam , Michael Krauthammer

The past decade has seen a revolution in genomic technologies that enable a flood of genome-wide profiling of chromatin marks. Recent literature tried to understand gene regulation by predicting gene expression from large-scale chromatin…

Machine Learning · Computer Science 2017-11-08 Ritambhara Singh , Jack Lanchantin , Arshdeep Sekhon , Yanjun Qi

Most existing sequence generation models produce outputs in one pass, usually left-to-right. However, this is in contrast with a more natural approach that humans use in generating content; iterative refinement and editing. Recent work has…

Computation and Language · Computer Science 2022-05-26 Machel Reid , Graham Neubig

Automatic spelling and grammatical correction systems are one of the most widely used tools within natural language applications. In this thesis, we assume the task of error correction as a type of monolingual machine translation where the…

Computation and Language · Computer Science 2018-10-02 Sina Ahmadi

While the multi-branch architecture is one of the key ingredients to the success of computer vision tasks, it has not been well investigated in natural language processing, especially sequence learning tasks. In this work, we propose a…

Computation and Language · Computer Science 2020-07-28 Yang Fan , Shufang Xie , Yingce Xia , Lijun Wu , Tao Qin , Xiang-Yang Li , Tie-Yan Liu

In clinical trials, ensuring the quality and validity of data for downstream analysis and results is paramount, thus necessitating thorough data monitoring. This typically involves employing edit checks and manual queries during data…

Other Statistics · Statistics 2026-01-15 Yuxi Zhao , Margaret Gamalo

Heterogeneous treatment effects (HTE) based on patients' genetic or clinical factors are of significant interest to precision medicine. Simultaneously modeling HTE and corresponding main effects for randomized clinical trials with…

Machine Learning · Statistics 2023-02-06 Heng Chen , Michael L. LeBlanc , James Y. Dai

Knowledge editing for large language models can offer an efficient solution to alter a model's behavior without negatively impacting the overall performance. However, the current approaches encounter issues with limited generalizability…

Computation and Language · Computer Science 2024-04-30 Ningyu Zhang , Bozhong Tian , Siyuan Cheng , Xiaozhuan Liang , Yi Hu , Kouying Xue , Yanjie Gou , Xi Chen , Huajun Chen

The attentional mechanism has proven to be effective in improving end-to-end neural machine translation. However, due to the intricate structural divergence between natural languages, unidirectional attention-based models might only capture…

Computation and Language · Computer Science 2016-04-25 Yong Cheng , Shiqi Shen , Zhongjun He , Wei He , Hua Wu , Maosong Sun , Yang Liu

Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhibit divergent outcomes under the same treatment conditions. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Florian Bürger , Martim Dias Gomes , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Facial attribute editing has mainly two objectives: 1) translating image from a source domain to a target one, and 2) only changing the facial regions related to a target attribute and preserving the attribute-excluding details. In this…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Ke Zhang , Yukun Su , Xiwang Guo , Liang Qi , Zhenbing Zhao

Instruction-based image editing holds immense potential for a variety of applications, as it enables users to perform any editing operation using a natural language instruction. However, current models in this domain often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Shelly Sheynin , Adam Polyak , Uriel Singer , Yuval Kirstain , Amit Zohar , Oron Ashual , Devi Parikh , Yaniv Taigman

Modeling attention in neural multi-source sequence-to-sequence learning remains a relatively unexplored area, despite its usefulness in tasks that incorporate multiple source languages or modalities. We propose two novel approaches to…

Computation and Language · Computer Science 2017-04-24 Jindřich Libovický , Jindřich Helcl

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

Computation and Language · Computer Science 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen

Multitask deep learning has been applied to patient outcome prediction from text, taking clinical notes as input and training deep neural networks with a joint loss function of multiple tasks. However, the joint training scheme of multitask…

Computation and Language · Computer Science 2023-01-26 Shaoxiong Ji , Pekka Marttinen

Language and vision-language models have shown impressive performance across a wide range of tasks, but their internal mechanisms remain only partly understood. In this work, we study how individual attention heads in text-generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Lorenzo Basile , Valentino Maiorca , Diego Doimo , Francesco Locatello , Alberto Cazzaniga

In this work, we explore multiple neural architectures adapted for the task of automatic post-editing of machine translation output. We focus on neural end-to-end models that combine both inputs $mt$ (raw MT output) and $src$ (source…

Computation and Language · Computer Science 2017-10-03 Marcin Junczys-Dowmunt , Roman Grundkiewicz

Answering multi-hop reasoning questions requires retrieving and synthesizing information from diverse sources. Language models (LMs) struggle to perform such reasoning consistently. We propose an approach to pinpoint and rectify multi-hop…

Computation and Language · Computer Science 2024-11-11 Mansi Sakarvadia

Attention layers -- which map a sequence of inputs to a sequence of outputs -- are core building blocks of the Transformer architecture which has achieved significant breakthroughs in modern artificial intelligence. This paper presents a…

Machine Learning · Computer Science 2023-07-24 Hengyu Fu , Tianyu Guo , Yu Bai , Song Mei

Computer vision-based methods have valuable use cases in precision medicine, and recognizing facial phenotypes of genetic disorders is one of them. Many genetic disorders are known to affect faces' visual appearance and geometry. Automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Ömer Sümer , Fabio Hellmann , Alexander Hustinx , Tzung-Chien Hsieh , Elisabeth André , Peter Krawitz
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