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Large language models (LLMs) have demonstrated impressive generative capabilities with the potential to innovate in medicine. However, the application of LLMs in real clinical settings remains challenging due to the lack of factual…

Computation and Language · Computer Science 2024-07-08 Rui Yang , Haoran Liu , Edison Marrese-Taylor , Qingcheng Zeng , Yu He Ke , Wanxin Li , Lechao Cheng , Qingyu Chen , James Caverlee , Yutaka Matsuo , Irene Li

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

The use of Large language models (LLMs) to augment clinical decision support systems is a topic with rapidly growing interest, but current shortcomings such as hallucinations and lack of clear source citations make them unreliable for use…

Human-Computer Interaction · Computer Science 2024-09-25 Daniel Jung , Alex Butler , Joongheum Park , Yair Saperstein

Assessing the capabilities and limitations of large language models (LLMs) has garnered significant interest, yet the evaluation of multiple models in real-world scenarios remains rare. Multilingual evaluation often relies on translated…

Computation and Language · Computer Science 2025-12-02 Varun Gumma , Ananditha Raghunath , Mohit Jain , Sunayana Sitaram

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Computation and Language · Computer Science 2023-11-10 Jason Holmes , Shuyuan Ye , Yiwei Li , Shi-Nan Wu , Zhengliang Liu , Zihao Wu , Jinyu Hu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Understanding the conversation abilities of Large Language Models (LLMs) can help lead to its more cautious and appropriate deployment. This is especially important for safety-critical domains like mental health, where someone's life may…

Computation and Language · Computer Science 2024-03-18 Alexander Marrapese , Basem Suleiman , Imdad Ullah , Juno Kim

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Empathetic dialogue is an indispensable part of building harmonious social relationships and contributes to the development of a helpful AI. Previous approaches are mainly based on fine small-scale language models. With the advent of…

Computation and Language · Computer Science 2024-07-29 Yushan Qian , Wei-Nan Zhang , Ting Liu

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

To enhance Large Language Models' (LLMs) reliability, calibration is essential -- the model's assessed confidence scores should align with the actual likelihood of its responses being correct. However, current confidence elicitation methods…

Computation and Language · Computer Science 2024-10-29 Yukun Huang , Yixin Liu , Raghuveer Thirukovalluru , Arman Cohan , Bhuwan Dhingra

Recent advancements in large language models (LLMs) like ChatGPT and LLaMA show promise in medical applications, yet challenges remain in medical language comprehension. This study presents Me-LLaMA, a new medical LLM family based on…

This study explores the effectiveness of Large Language Models (LLMs) for Automatic Question Generation in educational settings. Three LLMs are compared in their ability to create questions from university slide text without fine-tuning.…

Computation and Language · Computer Science 2024-09-17 Ivo Lodovico Molina , Valdemar Švábenský , Tsubasa Minematsu , Li Chen , Fumiya Okubo , Atsushi Shimada

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

Large language models (LLMs) like ChatGPT are increasingly used in academic writing, yet issues such as incorrect or fabricated references raise ethical concerns. Moreover, current content quality evaluations often rely on subjective human…

Computation and Language · Computer Science 2025-09-15 Jing Ren , Weiqi Wang

Large Language Models (LLMs) show promise for natural language generation in healthcare, but risk hallucinating factually incorrect information. Deploying LLMs for medical question answering necessitates reliable uncertainty estimation (UE)…

Computation and Language · Computer Science 2024-07-12 Jiaxin Wu , Yizhou Yu , Hong-Yu Zhou

Large Language Models (LLMs) are advanced Artificial Intelligence (AI) systems that have undergone extensive training using large datasets in order to understand and produce language that closely resembles that of humans. These models have…

Software Engineering · Computer Science 2023-08-10 Alessio Buscemi
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