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Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

The deployment of large language models (LLMs) within the healthcare sector has sparked both enthusiasm and apprehension. These models exhibit the remarkable capability to provide proficient responses to free-text queries, demonstrating a…

Computation and Language · Computer Science 2024-07-09 Zabir Al Nazi , Wei Peng

Large language models (LLMs), such as ChatGPT, are able to generate human-like, fluent responses for many downstream tasks, e.g., task-oriented dialog and question answering. However, applying LLMs to real-world, mission-critical…

Computation and Language · Computer Science 2023-03-10 Baolin Peng , Michel Galley , Pengcheng He , Hao Cheng , Yujia Xie , Yu Hu , Qiuyuan Huang , Lars Liden , Zhou Yu , Weizhu Chen , Jianfeng Gao

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

Large language models (LLMs) are currently being used to answer medical questions across a variety of clinical domains. Recent top-performing commercial LLMs, in particular, are also capable of citing sources to support their responses. In…

Computation and Language · Computer Science 2024-02-06 Kevin Wu , Eric Wu , Ally Cassasola , Angela Zhang , Kevin Wei , Teresa Nguyen , Sith Riantawan , Patricia Shi Riantawan , Daniel E. Ho , James Zou

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

In the face of rapidly expanding online medical literature, automated systems for aggregating and summarizing information are becoming increasingly crucial for healthcare professionals and patients. Large Language Models (LLMs), with their…

Computation and Language · Computer Science 2024-03-07 Niraj Yagnik , Jay Jhaveri , Vivek Sharma , Gabriel Pila

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

Computation and Language · Computer Science 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

To address challenges in the digital economy's landscape of digital intelligence, large language models (LLMs) have been developed. Improvements in computational power and available resources have significantly advanced LLMs, allowing their…

Computation and Language · Computer Science 2024-05-24 Yanxin Zheng , Wensheng Gan , Zefeng Chen , Zhenlian Qi , Qian Liang , Philip S. Yu

In recent years, the application of Large Language Models (LLMs) in healthcare has shown significant promise in improving the accessibility and dissemination of medical knowledge. This paper presents a detailed study of various LLMs trained…

Computation and Language · Computer Science 2024-08-09 Haoran Yu , Chang Yu , Zihan Wang , Dongxian Zou , Hao Qin

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

IMPORTANCE The response effectiveness of different large language models (LLMs) and various individuals, including medical students, graduate students, and practicing physicians, in pediatric ophthalmology consultations, has not been…

Computation and Language · Computer Science 2023-11-09 Jason Holmes , Rui Peng , Yiwei Li , Jinyu Hu , Zhengliang Liu , Zihao Wu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical…

Computation and Language · Computer Science 2024-10-18 Cheng Qian , Xianglong Shi , Shanshan Yao , Yichen Liu , Fengming Zhou , Zishu Zhang , Junaid Akram , Ali Braytee , Ali Anaissi

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive