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Quantum metrology utilizes entanglement for improving the sensitivity of measurements. Up to now the focus has been on the measurement of just one out of two non-commuting observables. Here we demonstrate a laser interferometer that…

MINFLUX microscopy allows for localization of fluorophores with nanometer precision using targeted scanning with an illumination profile with a minimum. However, current scanning patterns and the overall procedure are based on heuristics,…

Computational Physics · Physics 2026-04-17 Steffen Schultze , Helmut Grubmüller

We show that localisation microscopy of multiple weak, incoherent point sources with possibly different intensities in one spatial dimension is equivalent to estimating the amplitudes of a classical mixture of coherent states of a simple…

Quantum Physics · Physics 2020-02-17 Evangelia Bisketzi , Dominic Branford , Animesh Datta

We show that quantum computational imaging is advantageous in the setting of low-dose electron microscopy of beam-sensitive specimens. Two qudits placed near the electron beam enable full transfer of quantum information between the electron…

Quantum Physics · Physics 2026-04-14 Hiroshi Okamoto

We develop a quantum statistical framework for passive optical surface metrology. Modelling a surface as an incoherent ensemble of point emitters imaged through a diffraction-limited system, we employ techniques from quantum parameter…

Quantum Physics · Physics 2026-03-12 Jernej Frank , George Brumpton , Tommaso Tufarelli , Gerardo Adesso , Samanta Piano

Dual-comb interferometry harnesses the interference of two laser frequency combs to provide unprecedented capability in spectroscopy applications. In the past decade, the state-of-the-art systems have reached a point where the…

Quantum Physics · Physics 2023-09-20 Haowei Shi , Zaijun Chen , Scott E. Fraser , Mengjie Yu , Zheshen Zhang , Quntao Zhuang

We implement an estimator for determining the separation between two incoherent point sources. This estimator relies on image inversion interferometry and when used with the appropriate data analytics, it yields an estimate of the…

Optics · Physics 2016-05-31 Tang Zong Sheng , Kadir Durak , Alexander Ling

Quantum-correlated interferometer is a newly emerging tool in quantum technology that offers classical-limit-breaking phase sensitivity. But to date, there exists a configurational bottleneck for its practicability due to the low…

Atomic Physics · Physics 2025-01-10 Wei Du , Shuhe Wu , Dong Zhang , Jun Chen , Yiquan Yang , Peiyu Yang , Jinxian Guo , Guzhi Bao , Weiping Zhang

Using far field optical lithography, a single quantum dot is positioned within a pillar microcavity with a 50 nm accuracy. The lithography is performed in-situ at 10 K while measuring the quantum dot emission. Deterministic spectral and…

Materials Science · Physics 2009-01-05 A. Dousse , L. Lanco , J. Suffczynski , E. Semenova , A. Miard , A. Lemaitre , I. Sagnes , C. Roblin , J. Bloch , P. Senellart

The application of quantum estimation theory to the problem of imaging two incoherent point sources has recently led to new insights and better measurements for incoherent imaging and spectroscopy. To establish a more general limit beyond…

Quantum Physics · Physics 2019-01-09 Mankei Tsang

The diffraction of light imposes a fundamental limit on the resolution of light microscopes. This limit can be circumvented by creating and exploiting independent behaviors of the sample at length scales below the diffraction limit. In…

Biological Physics · Physics 2024-06-19 Mohamadreza Fazel , Michael J. Wester

Detecting if and when objects change is difficult in passive sub-diffraction imaging of dynamic scenes. We consider the best possible tradeoff between responsivity and accuracy for detecting a change from one arbitrary object model to…

Quantum Physics · Physics 2023-08-17 Michael R Grace , Saikat Guha , Zachary Dutton

Deterministic coupling between photonic nodes in a quantum network is an essential step towards implementing various quantum technologies. The omnidirectionality of free-standing emitters, however, makes this coupling highly inefficient, in…

Controlling quantum light-matter interactions at scales smaller than the diffraction limit at the single quantum emitter level is a critical challenge to the goal of advancing quantum technologies. We introduce a novel material platform…

We perform coherent non-linear spectroscopy of individual excitons strongly confined in single InAs quantum dots (QDs). The retrieval of their intrinsically weak four-wave mixing (FWM) response is enabled by a one-dimensional dielectric…

Mesoscale and Nanoscale Physics · Physics 2016-05-04 Q. Mermillod , T. Jakubczyk , V. Delmonte , A. Delga , E. Peinke , J-M. Gérard , J. Claudon , J. Kasprzak

Quantitative phase microscopy (QPM) and interferometric scattering (iSCAT) microscopy are powerful label-free imaging techniques and are widely used for biomedical applications. Each method, however, possesses distinct limitations: QPM,…

Optics · Physics 2025-03-20 Kohki Horie , Keiichiro Toda , Takuma Nakamura , Takuro Ideguchi

Fluorescence Correlation Spectroscopy (FCS) is widely used to detect and quantify diffusion processes at the molecular level. The molecules of which diffusion is studied are marked with fluorescent dyes. It is commonly maintained that this…

Biological Physics · Physics 2018-06-12 Mathias Lechelon , Marco Pettini

Quantum annealing is a new method for finding extrema of multidimensional functions. Based on an extension of classical, simulated annealing, this approach appears robust with respect to avoiding local minima. Further, unlike some of its…

chem-ph · Physics 2009-10-22 A. B. Finnila , M. A. Gomez , C. Sebenik , C. Stenson , J. D. Doll

We report both sub-diffraction-limited quantum metrology and quantum enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum correlated light as they diffuse through an extended region…

We present a fiber-based continuous-variable quantum key distribution system. In the scheme, a quantum signal of two non-orthogonal weak optical coherent states is sent through a fiber-based quantum channel. The receiver simultaneously…