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As big data continues to grow, statistical inference for multivariate functional data (MFD) has become crucial. Although recent advancements have been made in testing the equality of mean functions, research on testing linear hypotheses for…

Methodology · Statistics 2025-04-07 Tianming Zhu

Mendelian randomization uses genetic variants as instrumental variables to make causal inferences about the effects of modifiable risk factors on diseases from observational data. One of the major challenges in Mendelian randomization is…

Methodology · Statistics 2024-10-29 Youpeng Su , Siqi Xu , Yilei Ma , Ping Yin , Wing Kam Fung , Hongwei Jiang , Peng Wang

Longitudinal observational patient data can be used to investigate the causal effects of time-varying treatments on time-to-event outcomes. Several methods have been developed for controlling for the time-dependent confounding that…

Methodology · Statistics 2021-10-08 Ruth H. Keogh , Jon Michael Gran , Shaun R. Seaman , Gwyneth Davies , Stijn Vansteelandt

In a tie-breaker design (TBD), subjects with high values of a running variable are given some (usually desirable) treatment, subjects with low values are not, and subjects in the middle are randomized. TBDs are intermediate between…

Methodology · Statistics 2025-05-12 Tim P. Morrison , Art B. Owen

In response to the challenges of data mining, discriminant analysis continues to evolve as a vital branch of statistics. Our recently introduced method of vertex discriminant analysis (VDA) is ideally suited to handle multiple categories…

Applications · Statistics 2011-01-06 Tong Tong Wu , Kenneth Lange

High-dimensional linear classifiers, such as the support vector machine (SVM) and distance weighted discrimination (DWD), are commonly used in biomedical research to distinguish groups of subjects based on a large number of features.…

Methodology · Statistics 2017-10-20 Tianmeng Lyu , Eric F. Lock , Lynn E. Eberly

In many artificial intelligence and computer vision systems, the same object can be observed at distinct viewpoints or by diverse sensors, which raises the challenges for recognizing objects from different, even heterogeneous views.…

Machine Learning · Statistics 2020-04-03 Xiaoyun Li , Jie Gui , Ping Li

The monotone data augmentation (MDA) algorithm has been widely used to impute missing data for longitudinal continuous outcomes. Compared to a full data augmentation approach, the MDA scheme accelerates the mixing of the Markov chain,…

Methodology · Statistics 2025-12-23 Yongqiang Tang

Machine learning has recently been widely adopted to address the managerial decision making problems, in which the decision maker needs to be able to interpret the contributions of individual attributes in an explicit form. However, there…

Machine Learning · Computer Science 2019-10-28 Mengzhuo Guo , Qingpeng Zhang , Xiuwu Liao , Frank Youhua Chen , Daniel Dajun Zeng

Statistical tests that compare classification algorithms are univariate and use a single performance measure, e.g., misclassification error, $F$ measure, AUC, and so on. In multivariate tests, comparison is done using multiple measures…

Machine Learning · Statistics 2014-09-17 Olcay Taner Yildiz , Ethem Alpaydin

Functional linear discriminant analysis (FLDA) is a powerful tool that extends LDA-mediated multiclass classification and dimension reduction to univariate time-series functions. However, in the age of large multivariate and incomplete…

Machine Learning · Computer Science 2026-04-23 Rahul Bordoloi , Clémence Réda , Orell Trautmann , Saptarshi Bej , Olaf Wolkenhauer

In supervised classification problems, the test set may contain data points belonging to classes not observed in the learning phase. Moreover, the same units in the test data may be measured on a set of additional variables recorded at a…

Methodology · Statistics 2021-02-04 Michael Fop , Pierre-Alexandre Mattei , Charles Bouveyron , Thomas Brendan Murphy

Dependent data underlies many statistical studies in the social and health sciences, which often involve sensitive or private information. Differential privacy (DP) and in particular \textit{user-level} DP provide a natural formalization of…

Machine Learning · Statistics 2025-11-26 Valentin Roth , Marco Avella-Medina

Assessing variability according to distinct factors in data is a fundamental technique of statistics. The method commonly regarded to as analysis of variance (ANOVA) is, however, typically confined to the case where all levels of a factor…

Methodology · Statistics 2013-03-15 Steven Geinitz , Reinhard Furrer

In high-energy physics, with the search for ever smaller signals in ever larger data sets, it has become essential to extract a maximum of the available information from the data. Multivariate classification methods based on machine…

Uncovering the underlying ordinary differential equations (ODEs) that govern dynamic systems is crucial for advancing our understanding of complex phenomena. Traditional symbolic regression methods often struggle to capture the temporal…

Machine Learning · Computer Science 2025-06-24 Yang Chang , Kuang-Da Wang , Ping-Chun Hsieh , Cheng-Kuan Lin , Wen-Chih Peng

Mendelian randomization (MR) has become a popular approach to study the effect of a modifiable exposure on an outcome by using genetic variants as instrumental variables. A challenge in MR is that each genetic variant explains a relatively…

Methodology · Statistics 2020-10-13 Ting Ye , Jun Shao , Hyunseung Kang

Unsupervised Domain Adaptation (UDA) addresses the problem of performance degradation due to domain shift between training and testing sets, which is common in computer vision applications. Most existing UDA approaches are based on…

Computer Vision and Pattern Recognition · Computer Science 2019-05-14 Songsong Wu , Yan Yan , Hao Tang , Jianjun Qian , Jian Zhang , Xiao-Yuan Jing

We introduce Deep Linear Discriminant Analysis (DeepLDA) which learns linearly separable latent representations in an end-to-end fashion. Classic LDA extracts features which preserve class separability and is used for dimensionality…

Machine Learning · Computer Science 2016-02-18 Matthias Dorfer , Rainer Kelz , Gerhard Widmer

Estimating mutual information between continuous random variables is often intractable and extremely challenging for high-dimensional data. Recent progress has leveraged neural networks to optimize variational lower bounds on mutual…

Machine Learning · Computer Science 2020-12-01 Ruizhi Liao , Daniel Moyer , Polina Golland , William M. Wells