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Selective control in a population is the ability to control a member of the population while leaving the other members relatively unaffected. The concept of selective control is developed using cell death or apoptosis in heterogeneous cell…

Quantitative Methods · Quantitative Biology 2014-07-29 Diego Calzolari , Giovanni Paternostro , Patrick L. Harrington , Carlo Piermarocchi , Phillip M. Duxbury

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

Methodology · Statistics 2010-12-21 Xu Han , Weijie Gu , Jianqing Fan

Regression quantiles have asymptotic variances that depend on the conditional densities of the response variable given regressors. This paper develops a new estimate of the asymptotic variance of regression quantiles that leads any…

Econometrics · Economics 2019-09-27 Juan Carlos Escanciano , Chuan Goh

The use of weights provides an effective strategy to incorporate prior domain knowledge in large-scale inference. This paper studies weighted multiple testing in a decision-theoretic framework. We develop oracle and data-driven procedures…

Methodology · Statistics 2017-05-10 Pallavi Basu , T. Tony Cai , Kiranmoy Das , Wenguang Sun

Social scientists often study how a policy reform impacted a single targeted country. Increasingly, this is done with the synthetic control method (SCM). SCM models the country's counterfactual (non-reform or untreated) trajectory as a…

Applications · Statistics 2019-10-15 Elias Tuomaala

Generative Adversarial Networks (GANs) advance face synthesis through learning the underlying distribution of observed data. Despite the high-quality generated faces, some minority groups can be rarely generated from the trained models due…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Shuhan Tan , Yujun Shen , Bolei Zhou

This paper considers inference for conditional moment inequality models using a multiscale statistic. We derive the asymptotic distribution of this test statistic and use the result to propose feasible critical values that have a simple…

Applications · Statistics 2015-12-10 Timothy B. Armstrong , Hock Peng Chan

In this paper, we adopt results in nonlinear time series analysis for causal inference in dynamical settings.~Our motivation is policy analysis with panel data, particularly through the use of "synthetic control" methods. These methods…

Methodology · Statistics 2020-03-03 Yi Ding , Panos Toulis

We propose a way to remove the bias of a Poisson regression when the subjects are partially observed. In this paper we address this issue under certain assumptions about the missing-data generating process. We fix the total number of…

Statistics Theory · Mathematics 2014-07-08 Seyed Jalil Kazemitabar

In the paper, we suggest three tests on the validity of a factor model which can be applied for both small dimensional and large dimensional data. Both the exact and asymptotic distributions of the resulting test statistics are derived…

Statistics Theory · Mathematics 2016-06-24 Taras Bodnar , Markus Reiss

Estimating the counterfactual outcome of treatment is essential for decision-making in public health and clinical science, among others. Often, treatments are administered in a sequential, time-varying manner, leading to an exponentially…

Machine Learning · Statistics 2024-07-16 Shenghao Wu , Wenbin Zhou , Minshuo Chen , Shixiang Zhu

Although microarrays are routine analysis tools in biomedical research, they still yield noisy output that often requires experimental confirmation. Many studies have aimed at optimizing probe design and statistical analysis to tackle this…

Quantitative Methods · Quantitative Biology 2015-06-15 Alex E Pozhitkov , Peter A Noble , Jaroslaw Bryk , Diethard Tautz

Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects, are of interest because they may highlight genes associated…

Statistics Theory · Mathematics 2014-03-11 Vonn Walter , Fred A. Wright , Andrew B. Nobel

Inhibiting a signalling pathway concerns controlling the cellular processes of a cancer cell's viability, cell division, and death. Assay protocols created to see if the molecular structures of the drugs being tested have the desired…

Quantitative Methods · Quantitative Biology 2022-07-19 Roumen Anguelov , G Manjunath , Avulundiah E Phiri , Trevor T Nyakudya , Priyesh Bipath , June C Serem , Yvette N Hlophe

Asymptotic statistical theory for estimating functions is reviewed in a generality suitable for stochastic processes. Conditions concerning existence of a consistent estimator, uniqueness, rate of convergence, and the asymptotic…

Statistics Theory · Mathematics 2018-09-06 Jean Jacod , Michael Sørensen

Recently, we and several other authors have written about the possibilities of using stochastic approximation techniques for fitting variational approximations to intractable Bayesian posterior distributions. Naive implementations of…

Computation · Statistics 2014-01-14 Tim Salimans , David A. Knowles

We present an approach to inform decisions about nonresponse follow-up sampling. The basic idea is (i) to create completed samples by imputing nonrespondents' data under various assumptions about the nonresponse mechanisms, (ii) take…

Methodology · Statistics 2022-09-16 Thais Paiva , Jerry Reiter

In many applications, different populations are compared using data that are sampled in a biased manner. Under sampling biases, standard methods that estimate the difference between the population means yield unreliable inferences. Here we…

Statistics Theory · Mathematics 2019-11-12 Dave Zachariah , Petre Stoica

We consider the asymptotic properties of Approximate Bayesian Computation (ABC) for the realistic case of summary statistics with heterogeneous rates of convergence. We allow some statistics to converge faster than the ABC tolerance, other…

Computation · Statistics 2023-11-17 Caroline Lawless , Christian P. Robert , Judith Rousseau , Robin J. Ryder

This paper extends the literature on the theoretical properties of synthetic controls to the case of non-linear generative models, showing that the synthetic control estimator is generally biased in such settings. I derive a lower bound for…

Econometrics · Economics 2021-11-23 Oscar Engelbrektson