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Living organisms employ diverse strategies to navigate confined environments. Inspired by translocation observations on California blackworms (\textit{Lumbriculus variegatus}), we combine biological experiments and active-polymer…

Soft Condensed Matter · Physics 2025-10-21 K. R. Prathyusha , Paulami Sarkar , Justin Xu , Saad Bhamla

We investigate the nonequilibrium dynamics of semiflexible polymers driven by motor proteins (MPs) in two-dimensional motility assays under harmonic confinement. Using a coarse-grained agent-based model that incorporates stochastic motor…

Soft Condensed Matter · Physics 2025-09-09 Sandip Roy , Abhishek Chaudhuri , Anil Kumar Dasanna

Inspired by how the shape deformations in active organisms help them to migrate through disordered porous environments, we simulate active ring polymers in two-dimensional random porous media. Flexible and inextensible active ring polymers…

Soft Condensed Matter · Physics 2022-08-16 Ligesh Theeyancheri , Subhasish Chaki , Tapomoy Bhattacharjee , Rajarshi Chakrabarti

The motion of active polymers in a porous medium is shown to depend critically on flexibilty, activity and degree of polymerization. For given Peclet number, we observe a transition from localisation to diffusion as the stiffness of the…

Soft Condensed Matter · Physics 2019-07-17 Zahra Mokhtari , Annette Zippelius

We explore the impact of hydrodynamic interactions on the conformational and dynamical properties of wet tangentially-driven active polymers using multiparticle collision dynamics simulations. By analyzing active filaments with varying…

Soft Condensed Matter · Physics 2024-10-24 Loek van Steijn , Mohammad Fazelzadeh , Sara Jabbari-Farouji

We present an analytical and computational study characterizing the structural and dynamical properties of an active filament confined in cylindrical channels. We first outline the effects of the interplay between confinement and polar…

Soft Condensed Matter · Physics 2024-10-09 José Martín-Roca , Emanuele Locatelli , Valentino Bianco , Paolo Malgaretti , Chantal Valeriani

Active polymers possess numerous unique properties that are quite different from those observed in the system of small active molecule due to the intricate interplay between their activity and topological constraints. This study focuses on…

Soft Condensed Matter · Physics 2024-07-09 Jing Li , Bokai Zhang , Zhi-Yong Wang

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer…

Soft Condensed Matter · Physics 2024-07-29 Gokul Upadhyay , Rajeev Kapri , Anil Kumar Dasanna , Abhishek Chaudhuri

In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a…

Soft Condensed Matter · Physics 2018-03-26 A. Fiasconaro , J. J. Mazo , F. Falo

Single file translocation of a homopolymer through an active channel under the presence of a driving force is studied using Langevin dynamics simulation. It is shown that a channel with sticky walls and oscillating width could lead to…

Soft Condensed Matter · Physics 2013-02-01 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

Active polymer translocation through confined spaces is a key biological process underlying DNA transport through nuclear pores and actin filament dynamics in cell migration. Here, we use living polymer-like Tubifex tubifex worms as a model…

Soft Condensed Matter · Physics 2025-04-28 Marin Vatin , Rosa Sinaasappel , Renske Kamping , Chantal Valeriani , Emanuele Locatelli , Antoine Deblais

In this work, we compare the structural and dynamic behavior of active filaments in two dimensions using tangential and push-pull models, including a variant with passive end monomers. These models serve as valuable frameworks for…

The transport of deformable particles through porous media underlies a wealth of applications ranging from filtration to oil recovery to the transport and spreading of biological agents. Using direct numerical simulations, we analyze the…

Soft Condensed Matter · Physics 2020-06-09 Brato Chakrabarti , Charles Gaillard , David Saintillan

The conformational and dynamical properties of isolated flexible active polar linear polymers (APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear chains augmented by tangential active forces, both in a…

Soft Condensed Matter · Physics 2024-06-04 Christian A. Philipps , Gerhard Gompper , Roland G. Winkler

We consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the {\it trans} side. Using Langevin dynamics simulations we find that the rods facilitate…

Soft Condensed Matter · Physics 2022-11-15 Hamidreza Khalilian , Jalal Sarabadani , Tapio Ala-Nissila

Active filament-like systems propelling along their backbone exist across the scales ranging from motor-driven bio-filaments to worms and robotic chains. In macroscopic active filaments such as chain of robots, in contrast to their…

Soft Condensed Matter · Physics 2023-10-04 Mohammad Fazelzadeh , Ehsan Irani , Zahra Mokhtari , Sara Jabbari-Farouji

We consider a model of an extensible semiflexible filament moving in two dimensions on a motility assay of motor proteins represented explicitly as active harmonic linkers. Their heads bind stochastically to polymer segments within a…

Biological Physics · Physics 2021-08-31 Amir Shee , Nisha Gupta , Abhishek Chaudhuri , Debasish Chaudhuri

Active transport of biomolecules assisted by motor proteins is imperative for the proper functioning of cellular activities. Inspired by the diffusion of active agents in crowded cellular channels, we computationally investigate the…

Soft Condensed Matter · Physics 2022-01-19 Rajiblochan Sahoo , Ligesh Theeyancheri , Rajarshi Chakrabarti

Active semiflexible filament collectives, ranging from motor-driven cytoskeletal filaments to slender organisms such as cyanobacteria and worm aggregates, abound in nature. Yet how activity and flexibility jointly govern their organization,…

Soft Condensed Matter · Physics 2025-10-21 Twan Hooijschuur , Ehsan Irani , Antoine Deblais , Sara Jabbari-Farouji

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

Soft Condensed Matter · Physics 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon
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