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Ultrasound Localization Microscopy (ULM) enables imaging of vascular structures in the micrometer range by accumulating contrast agent particle locations over time. Precise and efficient target localization accuracy remains an active…

Image and Video Processing · Electrical Eng. & Systems 2023-11-08 Christopher Hahne , Georges Chabouh , Olivier Couture , Raphael Sznitman

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…

Ultrafast ultrasound localization microscopy (ULM), which has shown promising results in microvascular imaging, overcomes the typical trade-off between resolution and penetration depth. Combining ultrasound contrast agents and high frame…

Signal Processing · Electrical Eng. & Systems 2024-07-02 A. N. Madhavanunni , Niya Mariam Benoy , Mahesh Raveendranatha Panicker , Himanshu Shekhar

Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents (microbubbles) across numerous imaging frames. However, analysis of high-density regions…

Signal Processing · Electrical Eng. & Systems 2018-12-14 Ruud J. G. van Sloun , Oren Solomon , Matthew Bruce , Zin Z. Khaing , Hessel Wijkstra , Yonina C. Eldar , Massimo Mischi

Contrast-Enhanced Ultra-Sound (CEUS) has become a viable method for non-invasive, dynamic visualization in medical diagnostics, yet Ultrasound Localization Microscopy (ULM) has enabled a revolutionary breakthrough by offering ten times…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Christopher Hahne , Raphael Sznitman

Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical information for clinical diagnosis and evaluation of a broad-spectrum of pathologies. Recently, the emergence of super-resolution ultrasound…

Deep learning methods can be found in many medical imaging applications. Recently, those methods were applied directly to the RF ultrasound multi-channel data to enhance the quality of the reconstructed images. In this paper, we apply a…

Signal Processing · Electrical Eng. & Systems 2020-11-23 Nissim Peretz , Arie Feuer

Ultrasound Localization Microscopy (ULM) is an emerging technique that employs the localization of echogenic microbubbles (MBs) to finely sample and image the microcirculation beyond the diffraction limit of ultrasound imaging. Conventional…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 Sepideh K. Gharamaleki , Brandon Helfield , Hassan Rivaz

In ultrasound (US) imaging, various types of adaptive beamforming techniques have been investigated to improve the resolution and contrast-to-noise ratio of the delay and sum (DAS) beamformers. Unfortunately, the performance of these…

Image and Video Processing · Electrical Eng. & Systems 2020-02-25 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Convection of liquid metals drives large natural processes and is important in technical processes. Model experiments are conducted for research purposes where simulations are expensive and the clarification of open questions requires novel…

Fluid Dynamics · Physics 2024-04-18 David Weik , Zehua Dou , Dirk Räbiger , Tobias Vogt , Sven Eckert , Jürgen Czarske , Lars Büttner

Super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) offers a high-resolution view of microvascular structures. Yet, ULM image quality heavily relies on precise microbubble (MB) detection. Despite the crucial…

Artificial Intelligence · Computer Science 2026-01-15 Sepideh K. Gharamaleki , Brandon Helfield , Hassan Rivaz

In ultrasound (US) imaging, individual channel RF measurements are back-propagated and accumulated to form an image after applying specific delays. While this time reversal is usually implemented using a hardware- or software-based…

Image and Video Processing · Electrical Eng. & Systems 2019-07-17 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Diagnostic imaging plays a critical role in healthcare, serving as a fundamental asset for timely diagnosis, disease staging and management as well as for treatment choice, planning, guidance, and follow-up. Among the diagnostic imaging…

Signal Processing · Electrical Eng. & Systems 2021-09-24 Ruud JG van Sloun , Jong Chul Ye , Yonina C Eldar

Ultrasound (US) imaging is based on the time-reversal principle, in which individual channel RF measurements are back-propagated and accumulated to form an image after applying specific delays. While this time reversal is usually…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers (\mu m). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein, we…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Paul Xing , Jonathan Porée , Brice Rauby , Antoine Malescot , Éric Martineau , Vincent Perrot , Ravi L. Rungta , Jean Provost

Ultrasound Localization Microscopy (ULM) is a non-invasive technique that allows for the imaging of micro-vessels in vivo, at depth and with a resolution on the order of ten microns. ULM is based on the sub-resolution localization of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Brice Rauby , Paul Xing , Jonathan Porée , Maxime Gasse , Jean Provost

Traditional beamforming of medical ultrasound images relies on sampling rates significantly higher than the actual Nyquist rate of the received signals. This results in large amounts of data to store and process, imposing hardware and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Alon Mamistvalov , Ariel Amar , Naama Kessler , Yonina C. Eldar

Ultrasound Localization Microscopy (ULM) has recently enabled the mapping of the cerebral vasculature in vivo with a resolution ten times smaller than the wavelength used, down to ten microns. However, with frame rates up to 20.000 frames…

Medical Physics · Physics 2023-10-23 Erwan Hardy , Jonathan Poree , Hatim Belgharbi , Chloe Bourquin , Frederic Lesage , Jean Provost

Guided ultrasonic wave localization uses spatially distributed multistatic sensor arrays and generalized beamforming strategies to detect and locate damage across a structure. The propagation channel is often very complex. Methods can…

Signal Processing · Electrical Eng. & Systems 2024-10-30 Ishan D. Khurjekar , Joel B. Harley

Ultrasonic imaging is being used to obtain information about the acoustic properties of a medium by emitting waves into it and recording their interaction using ultrasonic transducer arrays. The Delay-And-Sum (DAS) algorithm forms images…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Georgios Pilikos , Lars Horchens , Tristan van Leeuwen , Felix Lucka
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