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Molecular property prediction (MPP) is integral to drug discovery and material science, but often faces the challenge of data scarcity in real-world scenarios. Addressing this, few-shot molecular property prediction (FSMPP) has been…

Machine Learning · Computer Science 2024-11-05 Liang Wang , Qiang Liu , Shaozhen Liu , Xin Sun , Shu Wu , Liang Wang

Molecular Property Prediction (MPP) task involves predicting biochemical properties based on molecular features, such as molecular graph structures, contributing to the discovery of lead compounds in drug development. To address data…

Machine Learning · Computer Science 2023-12-07 Xu Yao , Shuang Liang , Songqiao Han , Hailiang Huang

Pretrained equivariant graph neural networks based on spherical harmonics offer efficient and accurate alternatives to computationally expensive ab-initio methods, yet adapting them to new tasks and chemical environments still requires…

Machine Learning · Computer Science 2025-12-12 Dian Jin , Yancheng Yuan , Xiaoming Tao

Recently, the study of graph neural network (GNN) has attracted much attention and achieved promising performance in molecular property prediction. Most GNNs for molecular property prediction are proposed based on the idea of learning the…

Machine Learning · Computer Science 2021-04-15 Yingfang Yuan , Wenjun Wang , Wei Pang

Fueled by the ability to mine real-world graph data, GNN applications have experienced phenomenal growth. Sparse Matrix-Matrix Multiplication (SpMM) is a critical operator in GNNs. However, existing SpMM designs for GNNs struggle to adapt…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-18 Lixing Zhang , Guanhua Ye , Hongzheng Li , Shigang Li , Yingxia Shao

Graph classification aims to extract accurate information from graph-structured data for classification and is becoming more and more important in graph learning community. Although Graph Neural Networks (GNNs) have been successfully…

Machine Learning · Computer Science 2020-06-24 Ning Ma , Jiajun Bu , Jieyu Yang , Zhen Zhang , Chengwei Yao , Zhi Yu , Sheng Zhou , Xifeng Yan

To mitigate the detection performance drop caused by domain shift, we aim to develop a novel few-shot adaptation approach that requires only a few target domain images with limited bounding box annotations. To this end, we first observe…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Tao Wang , Xiaopeng Zhang , Li Yuan , Jiashi Feng

Pre-trained graph neural networks (GNNs) transfer well, but adapting them to downstream tasks remains challenging due to mismatches between pre-training objectives and task requirements. Graph prompt tuning offers a parameter-efficient…

Machine Learning · Computer Science 2026-02-06 Long D. Nguyen , Binh P. Nguyen

The recent success of graph neural networks has significantly boosted molecular property prediction, advancing activities such as drug discovery. The existing deep neural network methods usually require large training dataset for each…

Machine Learning · Computer Science 2021-02-17 Zhichun Guo , Chuxu Zhang , Wenhao Yu , John Herr , Olaf Wiest , Meng Jiang , Nitesh V. Chawla

Molecular property is usually observed with a limited number of samples, and researchers have considered property prediction as a few-shot problem. One important fact that has been ignored by prior works is that each molecule can be…

Machine Learning · Computer Science 2023-06-30 Xiang Zhuang , Qiang Zhang , Bin Wu , Keyan Ding , Yin Fang , Huajun Chen

Content-adaptive compression is crucial for enhancing the adaptability of the pre-trained neural codec for various contents. Although these methods have been very practical in neural image compression (NIC), their application in neural…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Zhenghao Chen , Luping Zhou , Zhihao Hu , Dong Xu

Model Predictive Control (MPC) is a method to control nonlinear systems with guaranteed stability and constraint satisfaction but suffers from high computation times. Approximate MPC (AMPC) with neural networks (NNs) has emerged to address…

Systems and Control · Electrical Eng. & Systems 2024-09-24 Henrik Hose , Alexander Gräfe , Sebastian Trimpe

The neighborhood scope (i.e., number of hops) where graph neural networks (GNNs) aggregate information to characterize a node's statistical property is critical to GNNs' performance. Two-stage approaches, training and validating GNNs for…

Machine Learning · Computer Science 2026-02-16 Paribesh Regmi , Rui Li , Kishan KC

Fine-tuning Large Language Models (LLMs) for clinical Natural Language Processing (NLP) poses significant challenges due to domain gap, limited data, and stringent hardware constraints. In this study, we evaluate four adapter…

Computation and Language · Computer Science 2025-07-29 Thanh-Dung Le , Ti Ti Nguyen , Vu Nguyen Ha , Symeon Chatzinotas , Philippe Jouvet , Rita Noumeir

While graph heterophily has been extensively studied in recent years, a fundamental research question largely remains nascent: How and to what extent will graph heterophily affect the prediction performance of graph neural networks (GNNs)?…

Machine Learning · Computer Science 2023-06-27 Shuaicheng Zhang , Haohui Wang , Si Zhang , Dawei Zhou

Quantum Computing promises to solve complex combinatorial optimization problems more efficiently than classical methods, with the Quantum Approximate Optimization Algorithm (QAOA) being a leading candidate. Recent fixed-parameter variations…

Quantum Physics · Physics 2026-03-04 Rodrigo Coelho , Georg Kruse , Jeanette Miriam Lorenz

This work presents a novel reconfigurable architecture for Low Latency Graph Neural Network (LL-GNN) designs for particle detectors, delivering unprecedented low latency performance. Incorporating FPGA-based GNNs into particle detectors…

Hardware Architecture · Computer Science 2024-01-19 Zhiqiang Que , Hongxiang Fan , Marcus Loo , He Li , Michaela Blott , Maurizio Pierini , Alexander Tapper , Wayne Luk

Molecular property prediction (MPP) is a cornerstone of drug discovery and materials science, yet conventional deep learning approaches depend on large labeled datasets that are often unavailable. Few-shot Molecular property prediction…

Machine Learning · Computer Science 2025-10-27 Xiangyang Xu , Hongyang Gao

In this paper, we look at cross-domain few-shot classification which presents the challenging task of learning new classes in previously unseen domains with few labelled examples. Existing methods, though somewhat effective, encounter…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Rashindrie Perera , Saman Halgamuge

Molecular property prediction (MPP) is a fundamental but challenging task in the computer-aided drug discovery process. More and more recent works employ different graph-based models for MPP, which have made considerable progress in…

Machine Learning · Computer Science 2023-12-29 Bangyi Zhao , Weixia Xu , Jihong Guan , Shuigeng Zhou
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