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We perform simulations of a system containing simple model proteins and a polymer representing chromatin. We study the interplay between protein-protein and protein-chromatin interactions, and the resulting condensates which arise due to…

Soft Condensed Matter · Physics 2022-07-20 Marco Ancona , Chris A. Brackley

Biomembranes, which are mainly composed of neutral and charged lipids, exhibit a large variety of functional structures and dynamics. Here, we report a coarse-grained molecular dynamics (MD) simulation of the phase separation and…

Soft Condensed Matter · Physics 2016-11-07 Hiroaki Ito , Yuji Higuchi , Naofumi Shimokawa

Microcanonical Monte Carlo simulations of a polydisperse soft-spheres model for liquids and colloids have been performed for very large polydispersity, in the region where a phase-separation is known to occur when the system (or part of it)…

Soft Condensed Matter · Physics 2011-08-31 L. A. Fernandez , V. Martin-Mayor , B. Seoane , P. Verrocchio

In this paper, we study the longtime asymptotic behavior of a phase separation process occurring in a three-dimensional domain containing a fluid flow of given velocity. This process is modeled by a viscous convective Cahn-Hilliard system,…

Analysis of PDEs · Mathematics 2018-03-13 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

A phase transition model for porous media in consolidation is studied. The model is able to describe the phenomenon of fluid-segregation during the consolidation process, i.e., the coexistence of two phases differing from fluid content…

Fluid Dynamics · Physics 2016-10-31 Pietro Artale Harris

We study diffusive dynamics of phase separation in a binary mixture, following critical quench, both in spatial dimensions $d=2$ and $d=3$. Particular focus in this work is to obtain information about effects of system size and correction…

Statistical Mechanics · Physics 2015-05-27 Suman Majumder , Subir K. Das

We report on recent progress in understanding pairing phenomena in low-density nuclear matter at small and moderate isospin asymmetry. A rich phase diagram has been found comprising various superfluid phases that include a homogeneous and…

Nuclear Theory · Physics 2014-04-04 Martin Stein , Armen Sedrakian , Xu-Guang Huang , John W. Clark , Gerd Röpke

We calculate the phase behavior of hard spheres with size polydispersity, using accurate free energy expressions for the fluid and solid phases. Cloud and shadow curves, which determine the onset of phase coexistence, are found exactly by…

Condensed Matter · Physics 2007-05-23 M. Fasolo , P. Sollich

We devise a soft, solvent-free, coarse-grained model for lipid bilayer membranes. The non-bonded interactions take the form of a weighted-density functional which allows us to describe the thermodynamics of self-assembly and packing effects…

Soft Condensed Matter · Physics 2010-06-09 Martin Hömberg , Marcus Müller

A description of phase separation kinetics for solid binary (A,B) mixtures in thin film geometry based on the Kawasaki spin-exchange kinetic Ising model is presented in a discrete lattice molecular field formulation. It is shown that the…

Statistical Mechanics · Physics 2009-11-13 Subir K. Das , Jürgen Horbach , Kurt Binder

In this work, we analytically investigate a multi-component system for describing phase separation and damage processes in solids. The model consists of a parabolic diffusion equation of fourth order for the concentration coupled with an…

Analysis of PDEs · Mathematics 2013-12-09 Elena Bonetti , Christian Heinemann , Christiane Kraus , Antonio Segatti

The sustenance of life depends on the high degree of organization that prevails through different levels of living organisms, from subcellular structures such as biomolecular complexes and organelles to tissues and organs. The physical…

Soft Condensed Matter · Physics 2019-01-14 Hanieh Falahati , Amir Haji-Akbari

The phase behavior of membrane proteins stems from a complex synergy with the amphiphilic molecules required for their solubilization. We show that ionization of a pH-sensitive surfactant, LDAO, bound to a bacterial photosynthetic protein,…

Soft Condensed Matter · Physics 2009-11-07 R. Piazza , M. Pierno , E. Vignati , G. Venturoli , F. Francia , A. Mallardi , G. Palazzo

The formation of polarized signaling domains on cell membranes is a fundamental example of biological pattern formation. While such patterns resemble structures from equilibrium phase separation, they are intrinsically non-equilibrium,…

Biological Physics · Physics 2025-12-10 Damiano Andreghetti , Alfredo Braunstein , Luca Dall'Asta , Andrea Gamba

Molecular sorting is a fundamental process that allows eukaryotic cells to distill and concentrate specific chemical factors in appropriate cell membrane subregions, thus endowing them with different chemical identities and functional…

Soft Condensed Matter · Physics 2022-11-09 Elisa Floris , Andrea Piras , Francesco Saverio Pezzicoli , Marco Zamparo , Luca Dall'Asta , Andrea Gamba

Phase separation in confined environments is a fundamental process underlying geological flows, porous filtration, emulsions, and intracellular organization. Yet, how confinement and activity jointly govern coarsening kinetics and…

Soft Condensed Matter · Physics 2025-12-11 Preethi M , Parameshwaran A , Bhaskar Sen Gupta

Using the formalism of rigorous statistical mechanics, we study the phenomena of phase separation and freezing-point depression upon freezing of solutions. Specifically, we devise an Ising-based model of a solvent-solute system and show…

Mathematical Physics · Physics 2007-05-23 Kenneth Alexander , Marek Biskup , Lincoln Chayes

Discrete element method simulations of confined bidisperse granular shear flows elucidate the balance between diffusion and segregation that can lead to either mixed or segregated states, depending on confining pressure. Results indicate…

Soft Condensed Matter · Physics 2018-09-24 Alexander M. Fry , Paul B. Umbanhowar , Julio M. Ottino , Richard M. Lueptow

Understanding the (de)mixing behavior of multicomponent lipid bilayers is an important step towards unraveling the nature of spatial composition heterogeneities in cellular membranes and their role in biological function. We use…

Soft Condensed Matter · Physics 2018-05-17 Shushan He , Lutz Maibaum

A diffuse-interface model for microstructure with an arbitrary number of components and phases was developed from basic thermodynamic and kinetic principles and formalized within a variational framework. The model includes a composition…

Materials Science · Physics 2011-07-28 Daniel A. Cogswell , W. Craig Carter