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We introduce a model of a totally asymmetric simple exclusion process (TASEP) on a tree network where the aggregate hopping rate is constant from level to level. With this choice for hopping rates the model shows the same phase diagram as…

Statistical Mechanics · Physics 2013-11-12 Peter Mottishaw , Bartlomiej Waclaw , Martin R. Evans

The totally asymmetric simple exclusion process (TASEP) is a stochastic model for the unidirectional dynamics of interacting particles on a $1$D-lattice that is much used in systems biology and statistical physics. Its master equation…

Statistical Mechanics · Physics 2024-08-01 Kilian Pioch , Thomas Kriecherbauer , Michael Margaliot , Lars Grüne

We develop a method for solving mathematical models of messenger RNA (mRNA) translation based on the totally asymmetric simple exclusion process (TASEP). Our main goal is to demonstrate that the method is versatile and applicable to…

Biological Physics · Physics 2020-05-19 Simon Scott , Juraj Szavits-Nossan

The totally asymmetric simple exclusion process (TASEP) is a stochastic model for the unidirectional flow of interacting particles on a 1D-lattice that is much used in systems biology and statistical physics. Its master equation describes…

Dynamical Systems · Mathematics 2026-04-20 Kilian Pioch , Lars Grüne , Thomas Kriecherbauer , Michael Margaliot

We present new results for the current as a function of transmission rate in the one dimensional totally asymmetric simple exclusion process (TASEP) with a blockage that lowers the jump rate at one site from one to r < 1. Exact finite…

comp-gas · Physics 2016-08-31 Steven A. Janowsky , Joel L. Lebowitz

We study a totally asymmetric simple exclusion process (TASEP) with one defect site, hopping rate $q<1$, near the system boundary. Regarding our system as a pair of uniform TASEP's coupled through the defect, we study various methods to…

Statistical Mechanics · Physics 2009-11-13 J. J. Dong , R. K. P. Zia , B. Schmittmann

Totally asymmetric simple exclusion process (TASEP) was originally introduced as a model for the traffic-like collective movement of ribosomes on a messenger RNA (mRNA) that serves as the track for the motor-like forward stepping of…

Statistical Mechanics · Physics 2019-08-14 Bhavya Mishra , Debashish Chowdhury

Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, exit, and elongation rates along the mRNA strand on the steady state…

Genomics · Quantitative Biology 2014-09-19 Gilad Poker , Michael Margaliot , Tamir Tuller

The totally asymmetric simple exclusion process (TASEP) is a paradigmatic lattice model for one-dimensional particle transport subject to excluded-volume interactions. Solving the inhomogeneous TASEP in which particles' hopping rates vary…

Statistical Mechanics · Physics 2023-10-31 Luca Ciandrini , Richmond L. Crisostomo , Juraj Szavits-Nossan

The steady-state currents and densities of a one-dimensional totally asymmetric exclusion process (TASEP) with particles that occlude an integer number ($d$) of lattice sites are computed using various mean field approximations and Monte…

Statistical Mechanics · Physics 2007-05-23 G. W. Lakatos , T. Chou

The process of protein synthesis in biological systems resembles a one dimensional driven lattice gas in which the particles have spatial extent, covering more than one lattice site. We expand the well studied Totally Asymmetric Exclusion…

Statistical Mechanics · Physics 2009-11-10 Leah B. Shaw , R. K. P. Zia , Kelvin H. Lee

Fundamental biological processes such as transcription and translation, where a genetic sequence is sequentially read by a macromolecule, have been well described by a classical model of non-equilibrium statistical physics, the totally…

Quantitative Methods · Quantitative Biology 2019-08-15 Jingkui Wang , Benjamin Pfeuty , Quentin Thommen , Carmen Romano , Marc Lefranc

We develop a power series method for the nonequilibrium steady state of the inhomogeneous one-dimensional totally asymmetric simple exclusion process (TASEP) in contact with two particle reservoirs and with site-dependent hopping rates in…

Statistical Mechanics · Physics 2018-05-31 Juraj Szavits-Nossan , M. Carmen Romano , Luca Ciandrini

We formulate and analyze the steady-state behavior of totally asymmetric simple exclusion processes (TASEPs) that contain periodically varying movement rates. In our models, particles at a majority sites hop to the right with rate $p_1$…

Statistical Mechanics · Physics 2007-05-23 Greg Lakatos , Tom Chou , Anatoly Kolomeisky

We extend the paradigmatic and versatile TASEP (Totally Asymmetric Simple Exclusion Process) for stochastic 1d transport to allow for two different particle species, each having specific entry and exit rates. We offer a complete mean-field…

Statistical Mechanics · Physics 2022-04-06 Pierre Bonnin , Ian Stansfield , M. Carmen Romano , Norbert Kern

The totally asymmetric simple exclusion process (TASEP), a well-known model in its strictly one-dimensional (chain) version, is generalized to cylinder (nanotube) and ribbon (nanoribbon) geometries. A mean-field theoretical description is…

Statistical Mechanics · Physics 2013-10-22 R. B. Stinchcombe , S. L. A. de Queiroz , M. A. G. Cunha , Belita Koiller

We study the totally asymmetric simple exclusion process (TASEP) on complex networks, as a paradigmatic model for transport subject to excluded volume interactions. Building on TASEP phenomenology on a single segment and borrowing ideas…

Statistical Mechanics · Physics 2011-08-09 I. Neri , N. Kern , A. Parmeggiani

The totally asymmetric simple exclusion process (TASEP) is a well studied example of far-from-equilibrium dynamics. Here, we consider a TASEP with open boundaries but impose a global constraint on the total number of particles. In other…

Statistical Mechanics · Physics 2008-07-02 D. A. Adams , B. Schmittmann , R. K. P. Zia

Messenger RNA translation is often studied by means of statistical-mechanical models based on the Asymmetric Simple Exclusion Process (ASEP), which considers hopping particles (the ribosomes) on a lattice (the polynucleotide chain). In this…

Subcellular Processes · Quantitative Biology 2010-05-06 L. Ciandrini , I. Stansfield , M. C. Romano

The process of protein synthesis in biological systems resembles a one dimensional driven lattice gas in which the particles (ribosomes) have spatial extent, covering more than one lattice site. Realistic, nonuniform gene sequences lead to…

Statistical Mechanics · Physics 2009-11-10 Leah B. Shaw , James P. Sethna , Kelvin H. Lee
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