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Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Instruction tuning is crucial for enabling Large Language Models (LLMs) to solve real-world tasks. Prior work has shown the effectiveness of instruction-tuning data synthesized solely from LLMs, raising a fundamental question: Do we still…

Personalization is a critical task in modern intelligent systems, with applications spanning diverse domains, including interactions with large language models (LLMs). Recent advances in reasoning capabilities have significantly enhanced…

Computation and Language · Computer Science 2025-05-26 Sichun Luo , Guanzhi Deng , Jian Xu , Xiaojie Zhang , Hanxu Hou , Linqi Song

Supervised learning is limited both by the quantity and quality of the labeled data. In the field of medical record tagging, writing styles between hospitals vary drastically. The knowledge learned from one hospital might not transfer well…

Computation and Language · Computer Science 2018-11-30 Yuhui Zhang , Allen Nie , James Zou

A common way to use large pre-trained language models for downstream tasks is to fine tune them using additional layers. This may not work well if downstream domain is a specialized domain whereas the large language model has been…

Computation and Language · Computer Science 2023-05-31 Vanessa Liao , Syed Shariyar Murtaza , Yifan Nie , Jimmy Lin

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

The goal of meta-learning is to train a model on a variety of learning tasks, such that it can adapt to new problems within only a few iterations. Here we propose a principled information-theoretic model that optimally partitions the…

Machine Learning · Statistics 2020-09-10 Heinke Hihn , Daniel A. Braun

The alignment process changes several properties of a large language model's (LLM's) output distribution. We analyze two aspects of post-alignment distributional shift of LLM responses. First, we re-examine previously reported reductions in…

Computation and Language · Computer Science 2025-05-13 Thom Lake , Eunsol Choi , Greg Durrett

The emergence of large language models (LLMs) has significantly impacted various fields, from natural language processing to sectors like medicine and finance. However, despite their rapid proliferation, the applications of LLMs in…

Information Theory · Computer Science 2025-05-06 Ali Maatouk , Kenny Chirino Ampudia , Rex Ying , Leandros Tassiulas

Self-supervision provides effective representations for downstream tasks without requiring labels. However, existing approaches lag behind fully supervised training and are often not thought beneficial beyond obviating or reducing the need…

Machine Learning · Computer Science 2019-10-30 Dan Hendrycks , Mantas Mazeika , Saurav Kadavath , Dawn Song

This paper presents a comprehensive exploration of leveraging Large Language Models (LLMs), specifically GPT-4, in the field of instructional design. With a focus on scaling evidence-based instructional design expertise, our research aims…

Computation and Language · Computer Science 2023-06-27 Gautam Yadav

It is imperative for Large language models (LLMs) to follow instructions with elaborate requirements (i.e. Complex Instructions Following). Yet, it remains under-explored how to enhance the ability of LLMs to follow complex instructions…

Computation and Language · Computer Science 2024-06-19 Qianyu He , Jie Zeng , Qianxi He , Jiaqing Liang , Yanghua Xiao

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Large "instruction-tuned" language models (i.e., finetuned to respond to instructions) have demonstrated a remarkable ability to generalize zero-shot to new tasks. Nevertheless, they depend heavily on human-written instruction data that is…

Computation and Language · Computer Science 2023-05-29 Yizhong Wang , Yeganeh Kordi , Swaroop Mishra , Alisa Liu , Noah A. Smith , Daniel Khashabi , Hannaneh Hajishirzi

Large language models (LLMs) have exhibited impressive performance and surprising emergent properties. However, their effectiveness remains limited by the fixed context window of the transformer architecture, posing challenges for…

Computation and Language · Computer Science 2025-06-16 Tianqi Du , Haotian Huang , Yifei Wang , Yisen Wang

Language models (LMs) have demonstrated remarkable capabilities in NLP, yet adapting them efficiently and robustly to specific tasks remains challenging. As their scale and complexity grow, fine-tuning LMs on labelled data often…

Computation and Language · Computer Science 2025-06-27 Zhengyan Shi

Merging Large Language Models (LLMs) is a cost-effective technique for combining multiple expert LLMs into a single versatile model, retaining the expertise of the original ones. However, current approaches often overlook the importance of…

Computation and Language · Computer Science 2024-06-21 Hasan Abed Al Kader Hammoud , Umberto Michieli , Fabio Pizzati , Philip Torr , Adel Bibi , Bernard Ghanem , Mete Ozay

Recently, pseudo label based semi-supervised learning has achieved great success in many fields. The core idea of the pseudo label based semi-supervised learning algorithm is to use the model trained on the labeled data to generate pseudo…

Machine Learning · Computer Science 2023-01-26 Zeping Min , Qian Ge , Cheng Tai

Safety for Large Language Models (LLMs) has been an ongoing research focus since their emergence and is even more relevant nowadays with the increasing capacity of those models. Currently, there are several guardrails in place for all…

Computation and Language · Computer Science 2025-12-25 Eduard Stefan Dinuta , Iustin Sirbu , Traian Rebedea

Even though large language models (LLMs) have demonstrated remarkable capability in solving various natural language tasks, the capability of an LLM to follow human instructions is still a concern. Recent works have shown great improvements…

Computation and Language · Computer Science 2024-03-05 Xinbo Wu , Lav R. Varshney