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While modern physics and biology satisfactorily explain the passage from the Big Bang to the formation of Earth and the first cells to present-day life, respectively, the origins of biochemical life still remain an open question. Since…

Populations and Evolution · Quantitative Biology 2025-02-25 Praful Gagrani , David Baum

The article provides a brief general introduction into the concepts of scaling, universality, and crossover scaling, plus the blob concept that provides an intuitive picture of crossover phenomena. We present the most important static and…

Soft Condensed Matter · Physics 2020-04-29 Burkhard Duenweg

Spontaneous self-assembly in molecular systems is a fundamental route to both biological and engineered soft matter. Simple micellisation, emulsion formation, and polymer mixing principles are well understood. However, the principles behind…

Soft Condensed Matter · Physics 2021-09-21 Alberto Scacchi , Sousa Javan Nikkhah , Maria Sammalkorpi , Tapio Ala-Nissila

Many microorganisms live and evolve in complex fluids. Examples include mammalian spermatozoa in cervical mucus, worms (e.g., \textit{C. elegans}) in wet soil, and bacteria (e.g., \textit{H. pylori}) in our stomach lining. Due to the…

Fluid Dynamics · Physics 2022-10-21 Paulo E. Arratia

We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent, using an innovative multi-scale methodology which treats the biopolymer at the microscopic scale as combined with a…

Computational Physics · Physics 2008-02-27 Massimo Bernaschi , Simone Melchionna , Sauro Succi , Maria Fyta , Efthimios Kaxiras

We investigate the process of biopolymer translocation through a narrow pore using a multiscale approach which explicitly accounts for the hydrodynamic interactions of the molecule with the surrounding solvent. The simulations confirm that…

Biological Physics · Physics 2009-01-16 Maria Fyta , Simone Melchionna , Sauro Succi , Efthimios Kaxiras

Traditionally, solubility and mixing belong to the realm of chemistry and material sciences and many standard textbooks on physical chemistry treat this problem, usually within the scope of thermodynamics. Here apart from thermodynamics we…

Condensed Matter · Physics 2007-05-23 Robert Holyst

We study a mutually coupled mesoscopic-macroscopic-shell system of equations modeling a dilute incompressible polymer fluid which is evolving and interacting with a flexible shell of Koiter type. The polymer constitutes a solvent-solute…

Analysis of PDEs · Mathematics 2021-03-17 Dominic Breit , Prince Romeo Mensah

The hydrophobic effect is the dominant force which drives a protein towards its native state, but its physics has not been thoroughly understood yet. We introduce an exactly solvable model of the solvation of non-polar molecules in water,…

Statistical Mechanics · Physics 2007-05-23 Pierpaolo Bruscolini , Lapo Casetti

Studying exoplanet atmospheres is essential for assessing their potential to host liquid water and their capacity to support life (their habitability). Each atmosphere uniquely influences the likelihood of surface liquid water, defining the…

Standard definitions of habitability assume that life requires the presence of planetary gravity wells to stabilize liquid water and regulate surface temperature. Here the consequences of relaxing this assumption are evaluated. Temperature,…

Earth and Planetary Astrophysics · Physics 2024-12-06 R. Wordsworth , C. Cockell

One of the unique features associated with the Earth is that the fraction of its surface covered by land is comparable to that spanned by its oceans and other water bodies. Here, we investigate how extraterrestrial biospheres depend on the…

Earth and Planetary Astrophysics · Physics 2019-01-04 Manasvi Lingam , Abraham Loeb

Apparent biodiversity on earth exists only if we compare different species separated from their environments. Meanwhile coexisting species have to be identical in terms of energetic interactions. Consider the biosphere as a network of…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Balciunas

Exoplanetary science continues to excite and surprise with its rich diversity. We discuss here some key aspects potentially influencing the range of exoplanetary terrestrial-type atmospheres which could exist in nature. We are motivated by…

In suitable environments, proteins, nucleic acids and certain synthetic polymers fold into unique conformations. This work shows that it is possible to construct lattice models of foldable heteropolymers by expressing the energy only in…

Soft Condensed Matter · Physics 2009-10-31 Michele Vendruscolo

Active matter agents consume internal energy or extract energy from the environment for locomotion and force generation. Already rather generic models, such as ensembles of active Brownian particles, exhibit phenomena, which are absent at…

Soft Condensed Matter · Physics 2020-07-27 Roland G. Winkler , Gerhard Gompper

The interaction between charged objects in solution is generally expected to recapitulate two central principles of electromagnetics: (i) like-charged objects repel, and (ii) they do so regardless of the sign of their electrical charge.…

Soft Condensed Matter · Physics 2022-12-27 Sida Wang , Rowan Walker-Gibbons , Bethany Watkins , Melissa Flynn , Madhavi Krishnan

Organisms leave a distinctive chemical signature in their environment because they synthesize those molecules that maximize their fitness. As a result, the relative concentrations of related chemical monomers in life-bearing environmental…

Biomolecules · Quantitative Biology 2011-05-05 Evan D. Dorn , Kenneth H. Nealson , Christoph Adami

The development of a coherent conceptual basis for the treatment of non-linear microscopic phenomena, such as, hydrodynamic interaction, finite extensibility, excluded volume and internal viscosity, in molecular theories of dilute polymer…

Statistical Mechanics · Physics 2021-07-16 J. Ravi Prakash

At the cutting edge of materials science, matter is designed to self-organize into structures that perform a wide range of functions. The past two decades have witnessed major innovations in the versatility of building blocks, ranging from…

Soft Condensed Matter · Physics 2022-09-26 Angus McMullen , Maitane Muñoz Basagoiti , Zorana Zeravcic , Jasna Brujic