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Optical frequency division (OFD) via optical frequency combs (OFC) has enabled a leap in microwave metrology leading to noise performance never explored before. Extending the method to millimeter-wave (mmW) and terahertz (THz)-wave domain…

Coherent diffraction imaging (CDI) for visualizing objects at atomic resolution has been realized as a promising tool for imaging single molecules. Drawbacks of CDI are associated with the difficulty of the numerical phase retrieval from…

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording,…

Optics · Physics 2007-05-23 Sergey A. Alexandrov , P. Meredith , T. J. McIntyre , A. V. Zvyagin

Three-dimensional molecular imaging of living cells is essential for unraveling cellular metabolism and response to therapies. However, existing volumetric methods, including fluorescence microscopy and quantitative phase imaging, either…

The realm of classical phase retrieval concerns itself with the arduous task of recovering a signal from its Fourier magnitude measurements, which are fraught with inherent ambiguities. A single-exposure intensity measurement is commonly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Yixiao Yang , Ran Tao , Kaixuan Wei , Jun Shi

By switching fluorophores on and off in either a deterministic or a stochastic manner, superresolution microscopy has enabled the imaging of biological structures at resolutions well beyond the diffraction limit. Superresolution optical…

Optoacoustic imaging technologies require fast and accurate signal pre-processing algorithms to enable widespread deployment in clinical and home-care settings. However, they still rely on the Discrete Fourier Transform (DFT) as the default…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Recent advancements in Text-to-3D generation have yielded remarkable progress, particularly through methods that rely on Score Distillation Sampling (SDS). While SDS exhibits the capability to create impressive 3D assets, it is hindered by…

Machine Learning · Computer Science 2024-07-30 Runjie Yan , Kailu Wu , Kaisheng Ma

High-resolution tissue imaging is often compromised by sample-induced optical aberrations that degrade resolution and contrast. While wavefront sensor-based adaptive optics (AO) can measure these aberrations, such hardware solutions are…

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to…

Medical Physics · Physics 2020-12-18 A. Alimi , S. Deslauriers-Gauthier , F. Matuschke , A. Müller , S. E. A. Muenzing , M. Axer , R. Deriche

A neural-network (NN)-based method for high-speed, high-definition dynamic optical coherence tomography (DOCT) using full-field swept-source optical coherence microscopy (FF-SS-OCM) is demonstrated. FF-SS-OCM provides high-definition OCT…

In ultrasound nondestructive testing, a widespread approach is to take synthetic aperture measurements from the surface of a specimen to detect and locate defects within it. Based on these measurements, imaging is usually performed using…

Signal Processing · Electrical Eng. & Systems 2020-12-09 Jan Kirchhof , Sebastian Semper , Christoph W. Wagner , Eduardo Pérez , Florian Römer , Giovanni Del Galdo

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

Single-shot coherent diffractive imaging (CDI) using intense XUV and soft X-ray pulses holds the promise to deliver information on the three dimensional shape as well as the optical properties of nano-scale objects in a single diffraction…

Optics · Physics 2025-11-25 Paul Tuemmler , Julia Apportin , Thomas Fennel , Christian Peltz

Accurately segmenting fluid in 3D optical coherence tomography (OCT) images is critical for detecting eye diseases but remains challenging. Traditional autoencoder-based methods struggle with resolution loss and information recovery. While…

Image and Video Processing · Electrical Eng. & Systems 2025-01-06 Khondker Fariha Hossain , Sharif Amit Kamran , Alireza Tavakkoli , George Bebis , Sal Baker
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