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Most visual generative models compress images into a latent space before applying diffusion or autoregressive modelling. Yet, existing approaches such as VAEs and foundation model aligned encoders implicitly constrain the latent space…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Sen Ye , Jianning Pei , Mengde Xu , Shuyang Gu , Chunyu Wang , Liwei Wang , Han Hu

Recently, deep generative models have become increasingly popular in unsupervised anomaly detection. However, deep generative models aim at recovering the data distribution rather than detecting anomalies. Besides, deep generative models…

Machine Learning · Computer Science 2019-11-15 Xuhong Wang , Ying Du , Shijie Lin , Ping Cui , Yuntian Shen , Yupu Yang

With the ever-increasing amount of data, the central challenge in multimodal learning involves limitations of labelled samples. For the task of classification, techniques such as meta-learning, zero-shot learning, and few-shot learning…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Nihar Bendre , Kevin Desai , Peyman Najafirad

Deep generative neural networks, such as Variational AutoEncoders (VAEs), offer an opportunity to better understand and control language models from the perspective of sentence-level latent spaces. To combine the controllability of VAE…

Computation and Language · Computer Science 2023-12-21 Yingji Zhang , Danilo S. Carvalho , Ian Pratt-Hartmann , André Freitas

Building robust medical machine learning systems requires pretraining strategies that exploit the intrinsic structure present in clinical data. We introduce Multiview Masked Autoencoder (MVMAE), a self-supervised framework that leverages…

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf

Multimodal recommender systems amalgamate multimodal information (e.g., textual descriptions, images) into a collaborative filtering framework to provide more accurate recommendations. While the incorporation of multimodal information could…

Information Retrieval · Computer Science 2024-02-27 Xin Zhou , Chunyan Miao

Independent component analysis is a core framework within blind source separation for recovering latent source signals from observed mixtures under statistical independence assumptions. In this work, we propose PDGMM-VAE, a source-oriented…

Machine Learning · Statistics 2026-04-24 Yuan-Hao Wei , Yan-Jie Sun

In recent years, deep generative models have been successfully adopted for various molecular design tasks, particularly in the life and material sciences. A critical challenge for pre-trained generative molecular design (GMD) models is to…

Machine Learning · Computer Science 2024-06-03 A N M Nafiz Abeer , Sanket Jantre , Nathan M Urban , Byung-Jun Yoon

A video prediction model that generalizes to diverse scenes would enable intelligent agents such as robots to perform a variety of tasks via planning with the model. However, while existing video prediction models have produced promising…

Computer Vision and Pattern Recognition · Computer Science 2021-06-22 Bohan Wu , Suraj Nair , Roberto Martin-Martin , Li Fei-Fei , Chelsea Finn

Representation learning and \emph{de novo} generation of proteins are pivotal computational biology tasks. Whilst natural language processing (NLP) techniques have proven highly effective for protein sequence modelling, structure modelling…

Quantitative Methods · Quantitative Biology 2025-01-08 Benoit Gaujac , Jérémie Donà , Liviu Copoiu , Timothy Atkinson , Thomas Pierrot , Thomas D. Barrett

Given the three dimensional complexity of a video signal, training a robust and diverse GAN based video generative model is onerous due to large stochasticity involved in data space. Learning disentangled representations of the data help to…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Sai Hemanth Kasaraneni

The field of advanced text-to-image generation is witnessing the emergence of unified frameworks that integrate powerful text encoders, such as CLIP and T5, with Diffusion Transformer backbones. Although there have been efforts to control…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Liang Chen , Shuai Bai , Wenhao Chai , Weichu Xie , Haozhe Zhao , Leon Vinci , Junyang Lin , Baobao Chang

Predicting customers' long-term revenue from sparse and irregular transaction data is central to marketing resource allocation in non-contractual settings, yet existing approaches face a trade-off. Traditional probabilistic customer base…

Machine Learning · Statistics 2026-04-27 Jeffrey Näf , Riana Valera Mbelson , Markus Meierer

Structure-based drug design (SBDD) aims to generate 3D ligand molecules that bind to specific protein targets. Existing 3D deep generative models including diffusion models have shown great promise for SBDD. However, it is complex to…

Biomolecules · Quantitative Biology 2024-03-01 Zhilin Huang , Ling Yang , Zaixi Zhang , Xiangxin Zhou , Yu Bao , Xiawu Zheng , Yuwei Yang , Yu Wang , Wenming Yang

Image and language modeling is of crucial importance for vision-language pre-training (VLP), which aims to learn multi-modal representations from large-scale paired image-text data. However, we observe that most existing VLP methods focus…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Sunan He , Taian Guo , Tao Dai , Ruizhi Qiao , Chen Wu , Xiujun Shu , Bo Ren

Deep neural networks are powerful tools for biomedical image segmentation. These models are often trained with heavy supervision, relying on pairs of images and corresponding voxel-level labels. However, obtaining segmentations of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-30 Evan M. Yu , Juan Eugenio Iglesias , Adrian V. Dalca , Mert R. Sabuncu

Recent advances in generative modeling show that pretrained representations can improve generation as conditioning features or alignment targets. Motivated by this, we study protein representations for predicting structures beyond…

Biomolecules · Quantitative Biology 2026-05-27 Taewon Kim , Hyosoon Jang , Hyunjin Seo , Seonghwan Seo , Hyeongwoo Kim , Wonho Zhung , Mingyeong Shin , Wooyoun Kim , Sungsoo Ahn

Time series sequence prediction and modelling has proven to be a challenging endeavor in real world datasets. Two key issues are the multi-dimensionality of data and the interaction of independent dimensions forming a latent output signal,…

Machine Learning · Computer Science 2020-10-09 Jakob Aungiers

Purpose: Handling heterogeneous and mixed data types has become increasingly critical with the exponential growth in real-world databases. While deep generative models attempt to merge diverse data views into a common latent space, they…

Machine Learning · Computer Science 2024-10-23 Alejandro Guerrero-López , Carlos Sevilla-Salcedo , Vanessa Gómez-Verdejo , Pablo M. Olmos