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The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that…

Soft Condensed Matter · Physics 2023-01-18 Matthias Merkel , Lisa Manning

Parkinson's disease (PD) shows heterogeneous, evolving brain-morphometry patterns. Modeling these longitudinal trajectories enables mechanistic insight, treatment development, and individualized 'digital-twin' forecasting. However, existing…

Machine Learning · Computer Science 2025-11-10 Xiaoda Wang , Yuji Zhao , Kaiqiao Han , Xiao Luo , Sanne van Rooij , Jennifer Stevens , Lifang He , Liang Zhan , Yizhou Sun , Wei Wang , Carl Yang

In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution. Our approach combines a spatio-temporal description of both processes into a…

Neurons and Cognition · Quantitative Biology 2019-05-27 Raphaël Sivera , Hervé Delingette , Marco Lorenzi , Xavier Pennec , Nicholas Ayache

Creating realistic 3D head assets for virtual characters that match a precise artistic vision remains labor-intensive. We present a novel framework that streamlines this process by providing artists with intuitive control over generated 3D…

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

Auto-regressive models have achieved impressive results in 2D image generation by modeling joint distributions in grid space. In this paper, we extend auto-regressive models to 3D domains, and seek a stronger ability of 3D shape generation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Xuelin Qian , Yu Wang , Simian Luo , Yinda Zhang , Ying Tai , Zhenyu Zhang , Chengjie Wang , Xiangyang Xue , Bo Zhao , Tiejun Huang , Yunsheng Wu , Yanwei Fu

This paper introduces a set of numerical methods for Riemannian shape analysis of 3D surfaces within the setting of invariant (elastic) second-order Sobolev metrics. More specifically, we address the computation of geodesics and geodesic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Emmanuel Hartman , Yashil Sukurdeep , Eric Klassen , Nicolas Charon , Martin Bauer

We model longitudinal macular thickness measurements to monitor the course of glaucoma and prevent vision loss due to disease progression. The macular thickness varies over a 6$\times$6 grid of locations on the retina with additional…

Applications · Statistics 2023-03-22 Erica Su , Robert E. Weiss , Kouros Nouri-Mahdavi , Andrew J. Holbrook

We propose a novel Transformer-based architecture for the task of generative modelling of 3D human motion. Previous work commonly relies on RNN-based models considering shorter forecast horizons reaching a stationary and often implausible…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Emre Aksan , Manuel Kaufmann , Peng Cao , Otmar Hilliges

Many surface cues support three-dimensional shape perception, but people can sometimes still see shape when these features are missing -- in extreme cases, even when an object is completely occluded, as when covered with a draped cloth. We…

Neurons and Cognition · Quantitative Biology 2023-01-11 Ilker Yildirim , Max H. Siegel , Amir A. Soltani , Shraman Ray Chaudhari , Joshua B. Tenenbaum

To understand how people look, interact, or perform tasks, we need to quickly and accurately capture their 3D body, face, and hands together from an RGB image. Most existing methods focus only on parts of the body. A few recent approaches…

Computer Vision and Pattern Recognition · Computer Science 2020-08-21 Vasileios Choutas , Georgios Pavlakos , Timo Bolkart , Dimitrios Tzionas , Michael J. Black

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

The 3D human pose is vital for modern computer vision and computer graphics, and its prediction has drawn attention in recent years. 3D human pose prediction aims at forecasting a human's future motion from the previous sequence. Ignoring…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Li Lin

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Accurate surface geometry representation is crucial in 3D visual computing. Explicit representations, such as polygonal meshes, and implicit representations, like signed distance functions, each have distinct advantages, making efficient…

Graphics · Computer Science 2025-09-26 Christian Stippel , Felix Mujkanovic , Thomas Leimkühler , Pedro Hermosilla

Constructing and animating humans is an important component for building virtual worlds in a wide variety of applications such as virtual reality or robotics testing in simulation. As there are exponentially many variations of humans with…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Ze Yang , Shenlong Wang , Sivabalan Manivasagam , Zeng Huang , Wei-Chiu Ma , Xinchen Yan , Ersin Yumer , Raquel Urtasun

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

Motivated by increasing trends of relating brain images to a clinical outcome of interest, we propose a functional domain selection (FuDoS) method that effectively selects subregions of the brain associated with the outcome. View each…

Applications · Statistics 2016-06-08 Ah Yeon Park , John A. D. Aston , Frederic Ferraty

We introduce a novel personalized Gaussian Process Experts (pGPE) model for predicting per-subject ADAS-Cog13 cognitive scores -- a significant predictor of Alzheimer's Disease (AD) in the cognitive domain -- over the future 6, 12, 18, and…

Machine Learning · Computer Science 2019-06-11 Ognjen Rudovic , Yuria Utsumi , Ricardo Guerrero , Kelly Peterson , Daniel Rueckert , Rosalind W. Picard

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo