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This paper studies inference on treatment effects in panel data settings with unobserved confounding. We model outcome variables through a factor model with random factors and loadings. Such factors and loadings may act as unobserved…

Econometrics · Economics 2023-12-05 Guido W. Imbens , Davide Viviano

We develop new semiparametric methods for estimating treatment effects. We focus on settings where the outcome distributions may be thick tailed, where treatment effects may be small, where sample sizes are large and where assignment is…

Methodology · Statistics 2023-08-24 Susan Athey , Peter J. Bickel , Aiyou Chen , Guido W. Imbens , Michael Pollmann

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

Methodology · Statistics 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi

Population synthesis involves generating synthetic yet realistic representations of a target population of micro-agents for behavioral modeling and simulation. Traditional methods, often reliant on target population samples, such as census…

In recent years, real-world external controls have grown in popularity as a tool to empower randomized placebo-controlled trials, particularly in rare diseases or cases where balanced randomization is unethical or impractical. However, as…

Methodology · Statistics 2024-11-14 Chenyin Gao , Shu Yang , Mingyang Shan , Wenyu Ye , Ilya Lipkovich , Douglas Faries

Synthetic control methods have gained popularity among causal studies with observational data, particularly when estimating the impacts of the interventions that are implemented to a small number of large units. Implementing the synthetic…

Methodology · Statistics 2020-05-29 Gyuhyeong Goh , Jisang Yu

We address the problem of ensemble selection in transfer learning: Given a large pool of source models we want to select an ensemble of models which, after fine-tuning on the target training set, yields the best performance on the target…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Andrea Agostinelli , Jasper Uijlings , Thomas Mensink , Vittorio Ferrari

This paper investigates the use of synthetic control methods for causal inference in macroeconomic settings when dealing with possibly nonstationary data. While the synthetic control approach has gained popularity for estimating…

Econometrics · Economics 2025-05-29 Zhentao Shi , Jin Xi , Haitian Xie

We study a continuous treatment effect model in the presence of treatment spillovers through social networks. We assume that one's outcome is affected not only by his/her own treatment but also by a (weighted) average of his/her neighbors'…

Econometrics · Economics 2023-01-12 Tadao Hoshino

Objective. Demographic groups are often represented at different rates in medical datasets. These differences can create bias in machine learning algorithms, with higher levels of performance for better-represented groups. One promising…

Machine Learning · Computer Science 2024-12-24 Daniel Smolyak , Arshana Welivita , Margrét V. Bjarnadóttir , Ritu Agarwal

We analyze the properties of the Synthetic Control (SC) and related estimators when the pre-treatment fit is imperfect. In this framework, we show that these estimators are generally biased if treatment assignment is correlated with…

Econometrics · Economics 2021-01-13 Bruno Ferman , Cristine Pinto

The randomized controlled trial (RCT) is the gold standard for estimating the average treatment effect (ATE) of a medical intervention but requires 100s-1000s of subjects, making it expensive and difficult to implement. While a cross-over…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Sayeri Lala , Niraj K. Jha

A common approach to synthetic data is to sample from a fitted model. We show that under general assumptions, this approach results in a sample with inefficient estimators and whose joint distribution is inconsistent with the true…

Statistics Theory · Mathematics 2026-02-18 Jordan Awan , Zhanrui Cai

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

In this short note, I outline conditions under which conditioning on Synthetic Control (SC) weights emulates a randomized control trial where the treatment status is independent of potential outcomes. Specifically, I demonstrate that if…

Methodology · Statistics 2022-11-04 Harsh Parikh

Background: Randomized controlled trials are often used to inform policy and practice for broad populations. The average treatment effect (ATE) for a target population, however, may be different from the ATE observed in a trial if there are…

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

Data imbalance in training data often leads to biased predictions from trained models, which in turn causes ethical and social issues. A straightforward solution is to carefully curate training data, but given the enormous scale of modern…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Moon Ye-Bin , Nam Hyeon-Woo , Wonseok Choi , Nayeong Kim , Suha Kwak , Tae-Hyun Oh

Electronic health records (EHR) often contain different rates of representation of certain subpopulations (SP). Factors like patient demographics, clinical condition prevalence, and medical center type contribute to this…

Machine Learning · Computer Science 2024-03-12 Oriel Perets , Nadav Rappoport