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Featurizing microscopy images for use in biological research remains a significant challenge, especially for large-scale experiments spanning millions of images. This work explores the scaling properties of weakly supervised classifiers and…

This paper shows that masked autoencoders (MAE) are scalable self-supervised learners for computer vision. Our MAE approach is simple: we mask random patches of the input image and reconstruct the missing pixels. It is based on two core…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Kaiming He , Xinlei Chen , Saining Xie , Yanghao Li , Piotr Dollár , Ross Girshick

Vision Transformers (ViTs) outperforms convolutional neural networks (CNNs) in several vision tasks with its global modeling capabilities. However, ViT lacks the inductive bias inherent to convolution making it require a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-01-11 Jiawei Mao , Honggu Zhou , Xuesong Yin , Yuanqi Chang. Binling Nie. Rui Xu

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

Large-scale cell microscopy screens are used in drug discovery and molecular biology research to study the effects of millions of chemical and genetic perturbations on cells. To use these images in downstream analysis, we need models that…

We investigated the adaptation and performance of Masked Autoencoders (MAEs) with Vision Transformer (ViT) architectures for self-supervised representation learning on one-dimensional (1D) ultrasound signals. Although MAEs have demonstrated…

Machine Learning · Computer Science 2025-08-29 Immanuel Roßteutscher , Klaus S. Drese , Thorsten Uphues

While transformers have surpassed convolutional neural networks (CNNs) in various computer vision tasks, microelectronics defect detection still largely relies on CNNs. We hypothesize that this gap is due to the fact that a) transformers…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Nikolai Röhrich , Alwin Hoffmann , Richard Nordsieck , Emilio Zarbali , Alireza Javanmardi

Masked Autoencoder (MAE) is a self-supervised approach for representation learning, widely applicable to a variety of downstream tasks in computer vision. In spite of its success, it is still not fully uncovered what and how MAE exactly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Jeongwoo Shin , Inseo Lee , Junho Lee , Joonseok Lee

Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ivan Svatko , Maxime Sanchez , Ihab Bendidi , Gilles Cottrell , Auguste Genovesio

This paper studies the potential of distilling knowledge from pre-trained models, especially Masked Autoencoders. Our approach is simple: in addition to optimizing the pixel reconstruction loss on masked inputs, we minimize the distance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-11 Yutong Bai , Zeyu Wang , Junfei Xiao , Chen Wei , Huiyu Wang , Alan Yuille , Yuyin Zhou , Cihang Xie

Bioacoustic recognition requires fine-grained acoustic understanding to distinguish similar-sounding species. However, many large-scale data repositories such as iNaturalist are weakly annotated, often with only a single positive species…

Sound · Computer Science 2026-05-15 Wuao Liu , Mustafa Chasmai , Subhransu Maji , Grant Van Horn

Masked Autoencoders (MAE) based on a reconstruction task have risen to be a promising paradigm for self-supervised learning (SSL) and achieve state-of-the-art performance across different benchmark datasets. However, despite its impressive…

Machine Learning · Computer Science 2023-03-28 Qi Zhang , Yifei Wang , Yisen Wang

Large, pretrained models are commonly finetuned with imagery that is heavily augmented to mimic different conditions and scales, with the resulting models used for various tasks with imagery from a range of spatial scales. Such models…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Colorado J. Reed , Ritwik Gupta , Shufan Li , Sarah Brockman , Christopher Funk , Brian Clipp , Kurt Keutzer , Salvatore Candido , Matt Uyttendaele , Trevor Darrell

The hematology analytics used for detection and classification of small blood components is a significant challenge. In particular, when objects exists as small pixel-sized entities in a large context of similar objects. Deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 H. Martin Gillis , Ming Hill , Paul Hollensen , Alan Fine , Thomas Trappenberg

The development of deep learning models in medical image analysis is majorly limited by the lack of large-sized and well-annotated datasets. Unsupervised learning does not require labels and is more suitable for solving medical image…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Zi'an Xu , Yin Dai , Fayu Liu , Weibing Chen , Yue Liu , Lifu Shi , Sheng Liu , Yuhang Zhou

Masked autoencoders (MAEs) have established themselves as a powerful method for unsupervised pre-training for computer vision tasks. While vanilla MAEs put equal emphasis on reconstructing the individual parts of the image, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-26 Leon Sick , Dominik Engel , Pedro Hermosilla , Timo Ropinski

Class Incremental Learning (CIL) aims to sequentially learn new classes while avoiding catastrophic forgetting of previous knowledge. We propose to use Masked Autoencoders (MAEs) as efficient learners for CIL. MAEs were originally designed…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Jiang-Tian Zhai , Xialei Liu , Andrew D. Bagdanov , Ke Li , Ming-Ming Cheng

Transformers have shown significant effectiveness for various vision tasks including both high-level vision and low-level vision. Recently, masked autoencoders (MAE) for feature pre-training have further unleashed the potential of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Huiyu Duan , Wei Shen , Xiongkuo Min , Danyang Tu , Long Teng , Jia Wang , Guangtao Zhai

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Finding an interpretable non-redundant representation of real-world data is one of the key problems in Machine Learning. Biological neural networks are known to solve this problem quite well in unsupervised manner, yet unsupervised…

Machine Learning · Computer Science 2020-10-13 Denis Kuzminykh , Laida Kushnareva , Timofey Grigoryev , Alexander Zatolokin
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