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Neural population activity in sensory cortex is organized on low-dimensional manifolds, but why such manifolds arise and what determines their geometry remain unclear. We model cortical populations as recurrent circuits driven by…

Neurons and Cognition · Quantitative Biology 2026-04-14 Vikas N. O'Reilly-Shah , Alessandro Maria Selvitella

The highly variable dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference but stand in apparent contrast to the deterministic response of neurons measured in vitro.…

Neurons and Cognition · Quantitative Biology 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

It is often remarked that neural networks fail to increase their uncertainty when predicting on data far from the training distribution. Yet naively using softmax confidence as a proxy for uncertainty achieves modest success in tasks…

Machine Learning · Computer Science 2021-06-10 Tim Pearce , Alexandra Brintrup , Jun Zhu

Neural networks predictions are unreliable when the input sample is out of the training distribution or corrupted by noise. Being able to detect such failures automatically is fundamental to integrate deep learning algorithms into robotics.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Antonio Loquercio , Mattia Segù , Davide Scaramuzza

The responses of synapses in the neocortex show highly stochastic and nonlinear behavior. The microscopic dynamics underlying this behavior, and its computational consequences during natural patterns of synaptic input, are not explained by…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ingo C. Kleppe , Hugh P. C. Robinson

Inferring intent from observed behavior has been studied extensively within the frameworks of Bayesian inverse planning and inverse reinforcement learning. These methods infer a goal or reward function that best explains the actions of the…

Machine Learning · Computer Science 2019-01-08 Siddharth Reddy , Anca D. Dragan , Sergey Levine

Predictive coding (PC) is a brain-inspired local learning algorithm that has recently been suggested to provide advantages over backpropagation (BP) in biologically relevant scenarios. While theoretical work has mainly focused on showing…

Neural and Evolutionary Computing · Computer Science 2023-06-01 Francesco Innocenti , Ryan Singh , Christopher L. Buckley

The goal of ordinal embedding is to represent items as points in a low-dimensional Euclidean space given a set of constraints in the form of distance comparisons like "item $i$ is closer to item $j$ than item $k$". Ordinal constraints like…

Machine Learning · Statistics 2016-06-24 Lalit Jain , Kevin Jamieson , Robert Nowak

We explore Bayesian reasoning as a means to quantify uncertainty in neural networks for question answering. Starting with a multilayer perceptron on the Iris dataset, we show how posterior inference conveys confidence in predictions. We…

Computation and Language · Computer Science 2025-12-22 Riccardo Di Sipio

One of the central aims of neuroscience is to reliably predict the behavioral response of an organism using its neural activity. If possible, this implies we can causally manipulate the neural response and design brain-computer-interface…

Neurons and Cognition · Quantitative Biology 2025-04-01 Jayanth R Taranath

Neural generative models can be used to learn complex probability distributions from data, to sample from them, and to produce probability density estimates. We propose a computational framework for developing neural generative models…

Machine Learning · Computer Science 2022-01-06 Alexander Ororbia , Daniel Kifer

Sequences of neuronal activation have long been implicated in a variety of brain functions. In particular, these sequences have been tied to memory formation and spatial navigation in the hippocampus, a region of mammalian brains.…

Neurons and Cognition · Quantitative Biology 2016-03-10 Zachary Roth

It is widely believed that the particular wiring observed within cortical columns boosts neural computation. We use rewiring of neural networks performing real-world cognitive tasks to study the validity of this argument. In a vast survey…

Neurons and Cognition · Quantitative Biology 2012-04-23 Ralph L. Stoop , Victor Saase , Clemens Wagner , Britta Stoop , Ruedi Stoop

A central problem in cognitive science and behavioural neuroscience as well as in machine learning and artificial intelligence research is to ascertain whether two or more decision makers (be they brains or algorithms) use the same…

Computer Vision and Pattern Recognition · Computer Science 2020-12-21 Robert Geirhos , Kristof Meding , Felix A. Wichmann

Proper confidence calibration of deep neural networks is essential for reliable predictions in safety-critical tasks. Miscalibration can lead to model over-confidence and/or under-confidence; i.e., the model's confidence in its prediction…

Machine Learning · Computer Science 2023-08-08 Shuang Ao , Stefan Rueger , Advaith Siddharthan

Effective decision making requires understanding the uncertainty inherent in a prediction. In regression, this uncertainty can be estimated by a variety of methods; however, many of these methods are laborious to tune, generate…

Machine Learning · Statistics 2021-12-02 Tianhui Zhou , Yitong Li , Yuan Wu , David Carlson

Despite intense recent research, the neural correlates of conscious visual perception remain elusive. The most established paradigm for studying brain mechanisms underlying conscious perception is to keep the physical sensory inputs…

Neurons and Cognition · Quantitative Biology 2014-03-21 Qi Li , Zachary Hill , Biyu J. He

The use of cortical field potentials rather than the details of spike trains as the basis for cognitive information processing is proposed. This results in a space of cognitive elements with natural metrics. Sets of spike trains may also be…

Disordered Systems and Neural Networks · Physics 2016-08-31 Henry C. Tuckwell

Current research in Computer Vision has shown that Convolutional Neural Networks (CNN) give state-of-the-art performance in many classification tasks and Computer Vision problems. The embedding of CNN, which is the internal representation…

Computer Vision and Pattern Recognition · Computer Science 2015-08-04 Axel Angel

This work simulates the developmental process of cortical neurogenesis, initiating from a single stem cell and governed by gene regulatory rules derived from mouse single-cell transcriptomic data. The developmental process spontaneously…

Neural and Evolutionary Computing · Computer Science 2026-04-17 Duan Zhou