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Density functional theory (DFT) and linear-response time-dependent density functional theory (LR-TDDFT) rely on an exchange-correlation (xc) approximation that provides not only energy but also its functional derivatives that enter the…

Chemical Physics · Physics 2026-04-08 Xiaoyu Zhang

The knowledge, embodied in machine learning models for intelligent systems, is commonly associated with time-consuming and costly processes such as large-scale data collection, data labelling, network training, and fine-tuning of models.…

Artificial Intelligence · Computer Science 2022-04-12 Amin Anjomshoaa , Edward Curry

Open-ended question answering requires models to find appropriate evidence to form wellreasoned, comprehensive and helpful answers. In practical applications, models also need to engage in extended discussions on potential scenarios closely…

Computation and Language · Computer Science 2024-12-17 Mingxu Tao , Dongyan Zhao , Yansong Feng

We present a hybrid scheme based on classical density functional theory and machine learning for determining the equilibrium structure and thermodynamics of inhomogeneous fluids. The exact functional map from the density profile to the…

Soft Condensed Matter · Physics 2023-12-12 Florian Sammüller , Sophie Hermann , Daniel de las Heras , Matthias Schmidt

Modern deep learning systems like PyTorch and Tensorflow are able to train enormous models with billions (or trillions) of parameters on a distributed infrastructure. These systems require that the internal nodes have the same memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-01 Yifan Ding , Nicholas Botzer , Tim Weninger

High volume of data, perceived as either challenge or opportunity. Deep learning architecture demands high volume of data to effectively back propagate and train the weights without bias. At the same time, large volume of data demands…

Machine Learning · Statistics 2018-05-15 Kumarjit Pathak , Prabhukiran G , Jitin Kapila , Nikit Gawande

An end-to-end platform for chemical science research has been developed that integrates data from computational and experimental approaches through a modern web-based interface. The platform offers a highly interactive visualization and…

Software Engineering · Computer Science 2017-07-17 Marcus D. Hanwell , Wibe A. de Jong , Christopher J. Harris

In this chapter we first outline some of the popular computing environments used for analysing neural data, followed by a brief discussion of 'software carpentry', basic tools and skills from software engineering that can be of great use to…

Neurons and Cognition · Quantitative Biology 2012-07-26 Robin A. A. Ince

Density functional theory (DFT) offers a desirable balance between quantitative accuracy and computational efficiency in practical many-electron calculations. Its central component, the exchange-correlation energy functional, has been…

Distributed computing platforms provide a robust mechanism to perform large-scale computations by splitting the task and data among multiple locations, possibly located thousands of miles apart geographically. Although such distribution of…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-24 Alok Singh , Eric Stephan , Malachi Schram , Ilkay Altintas

We develop a framework for combining differentiable programming languages with neural networks. Using this framework we create end-to-end trainable systems that learn to write interpretable algorithms with perceptual components. We explore…

Machine Learning · Computer Science 2017-03-03 Alexander L. Gaunt , Marc Brockschmidt , Nate Kushman , Daniel Tarlow

Kohn-Sham density functional theory is the base of modern computational approaches to electronic structures. Their accuracy vitally relies on the exchange-correlation energy functional, which encapsulates electron-electron interaction…

Computational Physics · Physics 2019-11-04 Ryo Nagai , Ryosuke Akashi , Osamu Sugino

ML4Chem is an open-source machine learning library for chemistry and materials science. It provides an extendable platform to develop and deploy machine learning models and pipelines and is targeted to the non-expert and expert users.…

Chemical Physics · Physics 2020-03-31 Muammar El Khatib , Wibe A de Jong

Although deep learning (DL) has already become a state-of-the-art technology for various data processing tasks, data security and computational overload problems often arise due to their high data and computational power dependency. To…

Quantum Physics · Physics 2022-04-08 Yunseok Kwak , Won Joon Yun , Jae Pyoung Kim , Hyunhee Cho , Minseok Choi , Soyi Jung , Joongheon Kim

While in principle exact, Kohn-Sham density functional theory -- the workhorse of computational chemistry -- must rely on approximations for the exchange-correlation functional. Despite staggering successes, present-day approximations still…

Neural networks that incorporate geometric relationships respecting SE(3) group transformations (e.g. rotations and translations) are increasingly important in molecular applications, such as molecular property prediction, protein structure…

Machine Learning · Computer Science 2025-10-21 Jose Siguenza , Bharath Ramsundar

Open-source large language models are becoming increasingly available and popular among researchers and practitioners. While significant progress has been made on open-weight models, open training data is a practice yet to be adopted by the…

Computation and Language · Computer Science 2024-11-19 Catherine Arnett , Eliot Jones , Ivan P. Yamshchikov , Pierre-Carl Langlais

The central quantity of density functional theory is the so-called exchange-correlation functional. This quantity encompasses all non-trivial many-body effects of the ground-state and has to be approximated in any practical application of…

Materials Science · Physics 2012-06-29 Miguel A. L. Marques , Micael J. T. Oliveira , Tobias Burnus

Density functional theory is the standard theory for computing the electronic structure of materials, which is based on a functional that maps the electron density to the energy. However, a rigorous form of the functional is not known and…

Materials Science · Physics 2021-12-02 Ryo Nagai , Ryosuke Akashi , Osamu Sugino

We consider density functionals for exchange and correlation energies in two-dimensional systems. The functionals are constructed by making use of exact constraints for the angular averages of the corresponding exchange and correlation…

Strongly Correlated Electrons · Physics 2010-02-25 E. Rasanen , S. Pittalis