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Graph deep learning has recently emerged as a powerful ML concept allowing to generalize successful deep neural architectures to non-Euclidean structured data. Such methods have shown promising results on a broad spectrum of applications…

Machine Learning · Computer Science 2022-05-16 Anees Kazi , Luca Cosmo , Seyed-Ahmad Ahmadi , Nassir Navab , Michael Bronstein

Graph neural networks (GNNs) are increasingly applied to physical design tasks such as congestion prediction and wirelength estimation, yet progress is hindered by inconsistent circuit representations and the absence of controlled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Zewei Zhou , Jiajun Zou , Jiajia Zhang , Ao Yang , Ruichao He , Haozheng Zhou , Ao Liu , Jiawei Liu , Leilei Jin , Shan Shen , Daying Sun

By leveraging recent progress of stochastic gradient descent methods, several works have shown that graphs could be efficiently laid out through the optimization of a tailored objective function. In the meantime, Deep Learning (DL)…

Machine Learning · Computer Science 2021-08-11 Loann Giovannangeli , Frederic Lalanne , David Auber , Romain Giot , Romain Bourqui

Neural Architecture Representation Learning aims to transform network models into feature representations for predicting network attributes, playing a crucial role in deploying and designing networks for real-world applications. Recently,…

Machine Learning · Computer Science 2025-06-10 Haizhao Jing , Haokui Zhang , Zhenhao Shang , Rong Xiao , Peng Wang , Yanning Zhang

The graph neural network (GNN) has been a powerful deep-learning tool in chemistry domain, due to its close connection with molecular graphs. Most GNN models collect and update atom and molecule features from the fed atom (and, in some…

Chemical Physics · Physics 2022-03-18 Yeji Kim , Yoonho Jeong , Jihoo Kim , Eok Kyun Lee , Won June Kim , Insung S. Choi

Learning distributions of graphs can be used for automatic drug discovery, molecular design, complex network analysis, and much more. We present an improved framework for learning generative models of graphs based on the idea of deep state…

Machine Learning · Computer Science 2021-12-07 Julian Stier , Michael Granitzer

Retrieval-augmented generation (RAG) has improved large language models (LLMs) by using knowledge retrieval to overcome knowledge deficiencies. However, current RAG methods often fall short of ensuring the depth and completeness of…

Computation and Language · Computer Science 2025-02-11 Shengjie Ma , Chengjin Xu , Xuhui Jiang , Muzhi Li , Huaren Qu , Cehao Yang , Jiaxin Mao , Jian Guo

Retrosynthetic planning, which aims to find a reaction pathway to synthesize a target molecule, plays an important role in chemistry and drug discovery. This task is usually modeled as a search problem. Recently, data-driven methods have…

Artificial Intelligence · Computer Science 2022-06-24 Shufang Xie , Rui Yan , Peng Han , Yingce Xia , Lijun Wu , Chenjuan Guo , Bin Yang , Tao Qin

Retrosynthesis, which aims to identify viable synthetic pathways for target molecules by decomposing them into simpler precursors, is often treated as a search problem. However, its complexity arises from multi-branched tree-structured…

Artificial Intelligence · Computer Science 2025-11-25 Chengyang Tian , Yuhang Chang , Yangpeng Zhang , Yang Liu

Two important tasks at the intersection of knowledge graphs and natural language processing are graph-to-text (G2T) and text-to-graph (T2G) conversion. Due to the difficulty and high cost of data collection, the supervised data available in…

Computation and Language · Computer Science 2020-12-11 Qipeng Guo , Zhijing Jin , Xipeng Qiu , Weinan Zhang , David Wipf , Zheng Zhang

Predictive tasks on relational databases are critical in real-world applications spanning e-commerce, healthcare, and social media. To address these tasks effectively, Relational Deep Learning (RDL) encodes relational data as graphs,…

Machine Learning · Computer Science 2025-06-10 Tianlang Chen , Charilaos Kanatsoulis , Jure Leskovec

The structural design of functional molecules, also called molecular optimization, is an essential chemical science and engineering task with important applications, such as drug discovery. Deep generative models and combinatorial…

Machine Learning · Computer Science 2022-01-25 Tianfan Fu , Wenhao Gao , Cao Xiao , Jacob Yasonik , Connor W. Coley , Jimeng Sun

Text-attributed graphs (TAGs) are prevalent on the web and research over TAGs such as citation networks, e-commerce networks and social networks has attracted considerable attention in the web community. Recently, large language models…

Computation and Language · Computer Science 2024-03-12 Yijian Qin , Xin Wang , Ziwei Zhang , Wenwu Zhu

Recently, deep generative models for molecular graphs are gaining more and more attention in the field of de novo drug design. A variety of models have been developed to generate topological structures of drug-like molecules, but…

Quantitative Methods · Quantitative Biology 2021-09-16 Yibo Li , Jianfeng Pei , Luhua Lai

In this paper, we demonstrate a computationally efficient new approach based on deep learning (DL) techniques for analysis, design, and optimization of electromagnetic (EM) nanostructures. We use the strong correlation among features of a…

Machine Learning · Computer Science 2020-02-13 Yashar Kiarashinejad , Sajjad Abdollahramezani , Ali Adibi

We investigate scaling and efficiency of the deep neural network multigrid method (DNN-MG). DNN-MG is a novel neural network-based technique for the simulation of the Navier-Stokes equations that combines an adaptive geometric multigrid…

Numerical Analysis · Mathematics 2021-06-16 Nils Margenberg , Robert Jendersie , Thomas Richter , Christian Lessig

Dynamic graph embedding has gained great attention recently due to its capability of learning low dimensional graph representations for complex temporal graphs with high accuracy. However, recent advances mostly focus on learning node…

Machine Learning · Computer Science 2022-04-29 Mengjia Xu , Apoorva Vikram Singh , George Em Karniadakis

Graph unlearning has emerged as a pivotal method to delete information from a pre-trained graph neural network (GNN). One may delete nodes, a class of nodes, edges, or a class of edges. An unlearning method enables the GNN model to comply…

Machine Learning · Computer Science 2024-06-11 Yash Sinha , Murari Mandal , Mohan Kankanhalli

Synthetic lethality (SL) is a promising gene interaction for cancer therapy. Recent SL prediction methods integrate knowledge graphs (KGs) into graph neural networks (GNNs) and employ attention mechanisms to extract local subgraphs as…

Machine Learning · Computer Science 2025-03-20 Xuexin Chen , Ruichu Cai , Zhengting Huang , Zijian Li , Jie Zheng , Min Wu

Dual-target therapeutic strategies have become a compelling approach and attracted significant attention due to various benefits, such as their potential in overcoming drug resistance in cancer therapy. Considering the tremendous success…

Machine Learning · Computer Science 2024-11-27 Xiangxin Zhou , Jiaqi Guan , Yijia Zhang , Xingang Peng , Liang Wang , Jianzhu Ma
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