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Resting-state functional Magnetic Resonance Imaging (fMRI) is a powerful imaging technique for studying functional development of the brain in utero. However, unpredictable and excessive movement of fetuses has limited clinical application…

Accurate segmentation of infant brain MRI is essential for quantifying developmental changes in structure and complexity. However, ongoing myelination and reduced tissue contrast make automated segmentation particularly challenging. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Nathalie Alexander , Arnaud Gucciardi , Umberto Michelucci

The aim of this study was to estimate the number of new cells and neurons added to the dentate gyrus across the lifespan, and to compare the rate of age-associated decline in neurogenesis across species. Data from mice (Mus musculus), rats…

Neurons and Cognition · Quantitative Biology 2011-05-05 Stanley E. Lazic

To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive to the cylinder's inner diameter. However, the shape of a…

Medical Physics · Physics 2020-08-18 Hong-Hsi Lee , Sune N. Jespersen , Els Fieremans , Dmitry S. Novikov

Diffusional kurtosis imaging (DKI) is a methodology for measuring the extent of non-Gaussian diffusion in biological tissue, which has shown great promise in clinical diagnosis, treatment planning and monitoring of many neurological…

Image and Video Processing · Electrical Eng. & Systems 2024-04-29 Megan E. Farquhar , Qianqian Yang , Viktor Vegh

The magnetorotational instability (MRI) is the leading candidate for driving turbulence, angular momentum transport, and accretion in astrophysical disks. I consider the linear theory of the MRI in a thin, equatorial disk in the Kerr…

Astrophysics · Physics 2009-11-10 Charles F. Gammie

In this paper we investigate the influence of radiative transport on the growth of the magnetorotational instability (MRI) in accretion discs. The analysis is performed by use of analytical and numerical means. We provide a general…

Solar and Stellar Astrophysics · Physics 2015-05-13 M. Flaig , R. Kissmann , W. Kley

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

Deep learning (DL) methods are increasingly outperforming classical approaches in brain imaging, yet their generalizability across diverse imaging cohorts remains inadequately assessed. As age and sex are key neurobiological markers in…

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Background: Differentiating radiation necrosis (RN) from tumor progression after stereotactic radiosurgery (SRS) remains a critical challenge in brain metastases. While histopathology represents the gold standard, its invasiveness limits…

Diffusion kurtosis imaging is an extension of diffusion tensor imaging that provides scientifically and clinically valuable information about brain tissue microstructure but suffers from poor robustness to noise, especially in voxels…

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain…

Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of…

Quantitative Methods · Quantitative Biology 2019-04-09 Andrey Chuhutin , Brian Hansen , Agnieszka Wlodarczyk , Trevor Owens , Noam Shemesh , Sune Nørhøj Jespersen

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

Purpose: Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues via the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has…

Medical Physics · Physics 2019-09-26 Aidin Arbabi , Jason Kai , Ali R Khan , Corey A Baron