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Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations.…
Lack of large, well-annotated emotional speech corpora continues to limit the performance and robustness of speech emotion recognition (SER), particularly as models grow more complex and the demand for multimodal systems increases. While…
In Genome-Wide Association Studies (GWAS) where multiple correlated traits have been measured on participants, a joint analysis strategy, whereby the traits are analyzed jointly, can improve statistical power over a single-trait analysis…
Image-to-image (I2I) translation methods based on generative adversarial networks (GANs) typically suffer from overfitting when limited training data is available. In this work, we propose a data augmentation method (ReMix) to tackle this…
Multimodal image-to-image translation (I2IT) aims to learn a conditional distribution that explores multiple possible images in the target domain given an input image in the source domain. Conditional generative adversarial networks (cGANs)…
Gene expression prediction plays a vital role in transcriptome-wide association studies (TWAS), which seek to establish associations between tissue gene expression and complex traits. Traditional models rely on genetic variants in close…
Genetic Algorithms (GAs) are explored as a tool for probing new physics with high dimensionality. We study the 19-dimensional pMSSM, including experimental constraints from all sources and assessing the consistency of potential signals of…
Most existing person re-identification (ReID) methods have good feature representations to distinguish pedestrians with deep convolutional neural network (CNN) and metric learning methods. However, these works concentrate on the similarity…
Motivation: Genome-Wide Association Studies (GWAS) seek to identify causal genomic variants associated with rare human diseases. The classical statistical approach for detecting these variants is based on univariate hypothesis testing, with…
Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…
Graph contrastive learning (GCL) shows great potential in unsupervised graph representation learning. Data augmentation plays a vital role in GCL, and its optimal choice heavily depends on the downstream task. Many GCL methods with…
Text-to-image generation and image captioning are recently emerged as a new experimental paradigm to assess machine intelligence. They predict continuous quantity accompanied by their sampling techniques in the generation, making evaluation…
Image Registration (IR) is the process of aligning two (or more) images of the same scene taken at different times, different viewpoints and/or by different sensors. It is an important, crucial step in various image analysis tasks where…
Feature-based image matching has extensive applications in computer vision. Keypoints detected in images can be naturally represented as graph structures, and Graph Neural Networks (GNNs) have been shown to outperform traditional deep…
Variational autoencoders (VAEs) have ushered in a new era of unsupervised learning methods for complex distributions. Although these techniques are elegant in their approach, they are typically not useful for representation learning. In…
In genome-wide association studies (GWASs), there is an increasing need for detecting the associations between a genetic variant and multiple traits. In studies of complex diseases, it is common to measure several potentially correlated…
In many scientific and engineering applications, one has to solve not one but a sequence of instances of the same problem. Often times, the problems in the sequence are linked in a way that allows intermediate results to be reused. A…
Motivated by empirical arguments that are well-known from the genome-wide association studies (GWAS) literature, we study the statistical properties of linear mixed models (LMMs) applied to GWAS. First, we study the sensitivity of LMMs to…
The Gaussian graphical model is a widely used tool for learning gene regulatory networks with high-dimensional gene expression data. Most existing methods for Gaussian graphical models assume that the data are homogeneous, i.e., all samples…
The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…