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The ground state electron density -- obtainable using Kohn-Sham Density Functional Theory (KS-DFT) simulations -- contains a wealth of material information, making its prediction via machine learning (ML) models attractive. However, the…

Crystal structures are characterized by atomic bases within a primitive unit cell that repeats along a regular lattice throughout 3D space. The periodic and infinite nature of crystals poses unique challenges for geometric graph…

Machine Learning · Computer Science 2024-03-19 Keqiang Yan , Cong Fu , Xiaofeng Qian , Xiaoning Qian , Shuiwang Ji

Molecular dynamic simulations are important in computational physics, chemistry, material, and biology. Machine learning-based methods have shown strong abilities in predicting molecular energy and properties and are much faster than DFT…

Molecular Networks · Quantitative Biology 2023-02-03 Zheng Yuan , Yaoyun Zhang , Chuanqi Tan , Wei Wang , Fei Huang , Songfang Huang

Graph neural networks face two fundamental challenges rooted in the linear structure of Euclidean vector spaces: (1) Current architectures represent geometry through vectors (directions, gradients), yet many tasks require matrix-valued…

Machine Learning · Computer Science 2026-04-23 Yuhan Peng , Junwen Dong , Yuzhi Zeng , Hao Li , Ce Ju , Huitao Feng , Diaaeldin Taha , Anna Wienhard , Kelin Xia

An extended range of energy stable flux reconstruction schemes, developed using a summation-by-parts approach, is presented on quadrilateral elements for various sets of polynomial bases. For the maximal order bases, a new set of correction…

Numerical Analysis · Mathematics 2022-06-03 Will Trojak , Rob Watson , Peter Vincent

This study explores the use of equivariant quantum neural networks (QNN) for generating molecular force fields, focusing on the rMD17 dataset. We consider a QNN architecture based on previous research and point out shortcomings in the…

Neural network force field (NNFF) is a method for performing regression on atomic structure-force relationships, bypassing expensive quantum mechanics calculation which prevents the execution of long ab-initio quality molecular dynamics…

Semiflexible polymers in poor solvents exhibit a rich variety of collapsed morphologies, including globules, toroids, and rodlike bundles, arising from the competition between attractive interactions and chain stiffness. Computer…

Statistical Mechanics · Physics 2026-01-22 Biman Bagchi

Mixed ionic-electronic conductors (MIECs) exhibit both high ionic and electronic conductivity to improve the battery performance. In this work, we investigate the mechanism and stability of transport channels in our recently developed MIEC…

Materials Science · Physics 2026-05-29 Selva Chandrasekaran Selvaraj , Daiwei Wang , Donghai Wang , Anh T. Ngo

Machine learning (ML) models utilizing structure-based features provide an efficient means for accurate property predictions across diverse chemical spaces. However, obtaining equilibrium crystal structures typically requires expensive…

Materials Science · Physics 2021-04-22 Yunxing Zuo , Mingde Qin , Chi Chen , Weike Ye , Xiangguo Li , Jian Luo , Shyue Ping Ong

Interfacial reconstruction between two-dimensional (2D) materials and metal substrates fundamentally governs heterostructure properties, yet conventional flat substrates fail to capture the continuous crystallographic landscape. Here, we…

Mesoscale and Nanoscale Physics · Physics 2026-01-01 Li-Qun Shen , Hao-Jin Wang , Mengzhao Sun , Yang Xiang , Xin-Ning Tian , Yue Chai , Yue Yang , Feng Ding , Xiao Kong , Marc-Georg Willinger , Zhu-Jun Wang

Learning from Demonstration (LfD) techniques enable robots to learn and generalize tasks from user demonstrations, eliminating the need for coding expertise among end-users. One established technique to implement LfD in robots is to encode…

A computational framework that leverages data from self-consistent field theory simulations with deep learning to accelerate the exploration of parameter space for block copolymers is presented. This is a substantial two-dimensional…

Materials Science · Physics 2023-07-04 Yao Xuan , Kris T. Delaney , Hector D. Ceniceros , Glenn H. Fredrickson

Large-scale foundation models have demonstrated remarkable versatility across a wide range of downstream tasks. However, fully fine-tuning these models incurs prohibitive computational costs, motivating the development of…

Machine Learning · Computer Science 2025-05-30 Chongjie Si , Xuankun Yang , Muqing Liu , Yadao Wang , Xiaokang Yang , Wenbo Su , Bo Zheng , Wei Shen

We present a way to dramatically accelerate Gaussian process models for interatomic force fields based on many-body kernels by mapping both forces and uncertainties onto functions of low-dimensional features. This allows for automated…

Computational Physics · Physics 2021-03-23 Yu Xie , Jonathan Vandermause , Lixin Sun , Andrea Cepellotti , Boris Kozinsky

Establishing the relationship between 3D structures and the energy states of molecular systems has proven to be a promising approach for learning 3D molecular representations. However, existing methods are limited to modeling the molecular…

Machine Learning · Computer Science 2025-02-27 Liang Wang , Shaozhen Liu , Yu Rong , Deli Zhao , Qiang Liu , Shu Wu , Liang Wang

Density functional theory (DFT) has become a standard tool for the study of point defects in materials. However, finding the most stable defective structures remains a very challenging task as it involves the solution of a multimodal…

Materials Science · Physics 2020-11-16 Marco Arrigoni , Georg K. H. Madsen

Molecular dynamics (MD) simulation is essential for various scientific domains but computationally expensive. Learning-based force fields have made significant progress in accelerating ab-initio MD simulation but are not fast enough for…

Machine Learning · Computer Science 2023-08-29 Xiang Fu , Tian Xie , Nathan J. Rebello , Bradley D. Olsen , Tommi Jaakkola

Designing novel functional proteins crucially depends on accurately modeling their fitness landscape. Given the limited availability of functional annotations from wet-lab experiments, previous methods have primarily relied on…

Machine Learning · Computer Science 2024-12-03 Zuobai Zhang , Pascal Notin , Yining Huang , Aurélie Lozano , Vijil Chenthamarakshan , Debora Marks , Payel Das , Jian Tang

Rapid development of universal machine learning potentials (uMLPs) and expansion of training data sets are reshaping the state of the art in atomistic simulation, highlighting the need for concurrent systematic benchmarking of their…

Materials Science · Physics 2026-03-02 Edan T. Marcial , Laxman Chaudhary , Olesya Gorbunova , Aleksey N. Kolmogorov